[1]刘志鹏,单超,潘灵婧,等.扫描式质子放疗系统自动化束斑测量与分析方法的设计和应用[J].中国医学物理学杂志,2022,39(10):1217-1224.[doi:DOI:10.3969/j.issn.1005-202X.2022.10.007]
　LIU Zhipeng,SHAN Chao,PAN Lingjing,et al.Design and application of automated spot measurement and analysis method for scanning proton radiation therapy system[J].Chinese Journal of Medical Physics,2022,39(10):1217-1224.[doi:DOI:10.3969/j.issn.1005-202X.2022.10.007]
点击复制

扫描式质子放疗系统自动化束斑测量与分析方法的设计和应用()
分享到：

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
39卷
期数:
2022年第10期
页码:
1217-1224
栏目:
医学放射物理
出版日期:
2022-11-02

文章信息/Info

Title:
Design and application of automated spot measurement and analysis method for scanning proton radiation therapy system
文章编号:
1005-202X（2022）10-1217-08
作者:
刘志鹏1; 单超1; 潘灵婧1; 王宇翔1; 王远远1; 卢晓明1; 2
1.中国科学技术大学附属第一医院离子医学中心（合肥离子医学中心）， 安徽 合肥 230088； 2.中国科学技术大学离子医学研究所， 安徽 合肥 230088
Author(s):
LIU Zhipeng1;  SHAN Chao1;  PAN Lingjing1;  WANG Yuxiang1;  WANG Yuanyuan1;  LU HsiaoMing1;  2
1. Hefei Ion Medical Center, the First Affiliated Hospital of University of Science and Technology of China, Hefei 230088, China 2. Ion Medical Research Institute, University of Science and Technology of China, Hefei 230088, China
关键词:
质子放疗; 笔形束扫描; 临床调试; 束斑分析; Lynx-PT
Keywords:
Keywords: proton radiation therapy pencil beam scanning clinical commissioning spot analysis Lynx-PT
分类号:
R318；TP317.4
DOI:
DOI:10.3969/j.issn.1005-202X.2022.10.007
文献标志码:
A
摘要:
目的：针对具有录像功能的闪烁体探测器Lynx-PT和笔形束扫描（PBS）质子放疗系统，设计一种质子束斑测量与分析方法，为PBS质子放疗系统的临床调试、束流建模和周期性质控测量提供可靠、高效的解决方案。方法：配置PBS质子放疗系统和Lynx-PT的相关参数，设计数据预处理和束斑分析流程，将两种数据处理流程嵌入自研软件（SpotCheck），实现从束斑采集到数据预处理再到束斑特性分析的全流程自动化。结果：SpotCheck输出的束斑尺寸结果与现有商业化软件（myQA, 比利时IBA公司）以及厂商的现场验收测量结果均保持一致，能成功识别所有束斑录像文件的数据质量问题，并将质子束流占用时间从4 d缩短至0.5 d。结论：本文方法的束斑尺寸计算结果准确、束斑采集速度快、数据处理流程自动化程度高，极大提升了PBS质子放疗系统临床调试和束流建模的效率。
Abstract:
Abstract: Objective To design a method for automated proton spot measurement and analysis based on video scintillation detector Lynx-PT and pencil beam scanning (PBS) proton radiation therapy system, which can offer a reliable and efficient solution for PBS proton radiation therapy system commissioning, beam modeling, and routine quality assurance measurements. Methods Configuration items of PBS proton radiation therapy system and Lynx-PT were set up based on the spot acquisition requirements, and a data preprocessing workflow and a spot analysis workflow were designed and embedded in the self-developed software (SpotCheck) to realize the automation of spot acquisition, data preprocessing and spot analysis. Results The spot sizes calculated by SpotCheck were consistent with the results from a commercial software package (myQA, IBA, Belgium) and manufacturers on-site acceptance data. By SpotCheck, all the video data quality events were successfully recognized, and the measurement duration was significantly reduced from 4 days to 0.5 day. Conclusion The proposed method can provide accurate spot sizes, rapid spot acquisition and highly automated data processing, greatly improving the quality and efficiency of clinical commissioning and beam modeling.

相似文献/References:

[1]阳露,刘红冬,陈志,等. 基于TOPAS计算的磁场下质子辐射剂量分析[J].中国医学物理学杂志,2017,34(3):217.[doi:10.3969/j.issn.1005-202X.2017.03.001]
　[J].Chinese Journal of Medical Physics,2017,34(10):217.[doi:10.3969/j.issn.1005-202X.2017.03.001]
[2]刘春波,皮一飞,徐遥,等.质子放疗计划解析与传输软件开发[J].中国医学物理学杂志,2018,35(4):373.[doi:DOI:10.3969/j.issn.1005-202X.2018.04.001]
　LIU Chunbo,PI Yifei,XU Yao,et al.Development of proton radiotherapy plan analysis and transmission software[J].Chinese Journal of Medical Physics,2018,35(10):373.[doi:DOI:10.3969/j.issn.1005-202X.2018.04.001]
[3]汪金龙,L. Alberto Cruz,刘铮铮,等. 权重适配的布拉格峰展宽方法[J].中国医学物理学杂志,2019,36(1):50.[doi:DOI:10.3969/j.issn.1005-202X.2019.01.010]
　WANG Jinlong,L. ALBERTO Cruz,LIU Zhengzheng,et al. Weight adaption-based spread-out Bragg peak method[J].Chinese Journal of Medical Physics,2019,36(10):50.[doi:DOI:10.3969/j.issn.1005-202X.2019.01.010]
[4]徐伟,杨涛,解传滨,等. 质子点扫描技术与光子Tomotherapy在前列腺癌应用中的剂量学比较[J].中国医学物理学杂志,2019,36(10):1129.[doi:DOI:10.3969/j.issn.1005-202X.2019.10.003]
　XU Wei,YANG Tao,XIE Chuanbin,et al. Dosimetric comparison between single spot scanning of proton therapy and tomotherapy for prostate cancer[J].Chinese Journal of Medical Physics,2019,36(10):1129.[doi:DOI:10.3969/j.issn.1005-202X.2019.10.003]
[5]吴韦清,卢晓光,郑仁超,等.国内首台迈胜PBS质子治疗系统的束流特性分析[J].中国医学物理学杂志,2024,41(3):282.[doi:DOI:10.3969/j.issn.1005-202X.2024.03.003]
　WU Weiqing,LU Xiaoguang,ZHENG Renchao,et al.Analysis of beam characteristics of the first Mevion pencil beam scanning proton therapy system in China[J].Chinese Journal of Medical Physics,2024,41(10):282.[doi:DOI:10.3969/j.issn.1005-202X.2024.03.003]
[6]郑仁超,卢晓光,吴韦清,等.PBS质子治疗系统快速日检QA方案的应用研究[J].中国医学物理学杂志,2024,41(10):1206.[doi:DOI:10.3969/j.issn.1005-202X.2024.10.003]
　ZHENG Renchao,LU Xiaoguang,WU Weiqing,et al.Application of rapid daily quality assurance for pencil beam scanning proton therapy system[J].Chinese Journal of Medical Physics,2024,41(10):1206.[doi:DOI:10.3969/j.issn.1005-202X.2024.10.003]

备注/Memo

备注/Memo:
【收稿日期】2022-05-06 【作者简介】刘志鹏，硕士研究生，工程师，研究方向：放疗设备质控和QA自动化系统开发，E-mail: liuzhipeng@himc.org.cn 【通信作者】卢晓明，博士，教授，研究方向：医学物理，E-mail: hmlu@himc.org.cn
更新日期/Last Update: 2022-10-27