[1]汪金龙,L. Alberto Cruz,刘铮铮,等. 权重适配的布拉格峰展宽方法[J].中国医学物理学杂志,2019,36(1):50-54.[doi:DOI:10.3969/j.issn.1005-202X.2019.01.010]
 WANG Jinlong,L. ALBERTO Cruz,LIU Zhengzheng,et al. Weight adaption-based spread-out Bragg peak method[J].Chinese Journal of Medical Physics,2019,36(1):50-54.[doi:DOI:10.3969/j.issn.1005-202X.2019.01.010]
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 权重适配的布拉格峰展宽方法()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
36卷
期数:
2019年第1期
页码:
50-54
栏目:
医学放射物理
出版日期:
2019-01-25

文章信息/Info

Title:
 Weight adaption-based spread-out Bragg peak method
文章编号:
1005-202X(2019)01-0050-05
作者:
 汪金龙1L. Alberto Cruz1刘铮铮1雷海2韦瑶1张炜3彭晟1
 1.新瑞阳光粒子医疗装备(无锡)有限公司, 江苏 无锡 214021; 2.南京大学物理学院, 江苏 南京 210093; 3.国家超级计算无锡中心, 江苏 无锡 214021
Author(s):
 WANG Jinlong1 L. ALBERTO Cruz 1 LIU Zhengzheng1 LEI Hai2 WEI Yao1 ZHANG Wei3 PENG Sheng1
 1. NewRT Corporation Ltd., Wuxi 214021, China; 2. School of Physics, Nanjing University, Nanjing 210093, China; 3. National Supercomputing Center in Wuxi, Wuxi 214021, China
关键词:
 布拉格峰展宽质子放疗蒙特卡洛模拟FLUKA权重适配
Keywords:
 Keywords: spread-out Bragg peak proton therapy Monte Carlo simulation FLUKA weight adaption
分类号:
R312
DOI:
DOI:10.3969/j.issn.1005-202X.2019.01.010
文献标志码:
A
摘要:
 目的:提供一种权重适配的布拉格峰展宽(SOBP)方法,得到平滑的展宽布拉格峰。 方法:通过重新拟合质子能量-射程的关系(盖格法则),找出适配函数的函数形式,并对权重进行重新适配,通过求敏感参数k,得到平滑的SOBP,最后用蒙特卡洛程序FLUKA进行验证。 结果:SOBP的形状对参数k比参数P更加敏感,拟合得到4~32 cm的SOBP,中间平坦区偏差不超过±2%,并解决中间区坍塌的问题。 结论:蒙特卡洛模拟检验了权重适配的SOBP方法的有效性。
Abstract:
 Abstract: Objective To develop a spread-out Bragg peak (SOBP) method using weight adaption for obtaining a smooth spread-out Bragg peak. Methods By refitting the proton rang-energy relation (Geiger’s law), the adaptation function was obtained, and the weight was re-adjusted. The smooth SOBP was obtained by finding the sensitive parameter k, and finally the proposed method was verified by Monte Carlo code FLUKA. Results The shape of SOBP was more sensitive to the parameter k than parameter P. A SOBP of 4-32 cm was obtained, and the deviation in the middle flat region was no more than ±2%, which solved the problem of collapse in the middle region. Conclusion The effectiveness of SOBP method based on weight adaptation is verified with Monte Carlo simulation.

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备注/Memo

备注/Memo:
 【收稿日期】2018-09-03
【作者简介】汪金龙,应用物理工程师兼注册核安全工程师,研究方向:质子治疗、瞬发伽马成像、辐射防护等,E-mail: dg1726010@smail.nju.edu.cn
【通信作者】彭晟,NewRT首席执行官,E-mail: speng@newrt.com
更新日期/Last Update: 2019-01-24