[1]李巧艺,白龙,徐庆丰,等.放射治疗中小野剂量学的研究进展[J].中国医学物理学杂志,2020,37(12):1477-1481.[doi:DOI:10.3969/j.issn.1005-202X.2020.12.001]
　LI Qiaoyi,BAI Long,XU Qingfeng,et al.Current research progress of small-field dosimetry in radiotherapy[J].Chinese Journal of Medical Physics,2020,37(12):1477-1481.[doi:DOI:10.3969/j.issn.1005-202X.2020.12.001]
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放射治疗中小野剂量学的研究进展()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
37
期数:
2020年第12期
页码:
1477-1481
栏目:
医学放射物理
出版日期:
2020-12-30

文章信息/Info

Title:
Current research progress of small-field dosimetry in radiotherapy
文章编号:
1005-202X（2020）12-1477-05
作者:
李巧艺1; 白龙1; 徐庆丰1; 陈蕾2; 徐云波1; 周阳1; 唐华南1; 周莉1
1.四川大学华西医院肿瘤中心（生物治疗国家重点实验室）放疗科， 四川 成都 610041； 2.四川大学原子核科学技术研究所辐射物理及技术教育部重点实验室， 四川 成都 610065
Author(s):
LI Qiaoyi1;  BAI Long1;  XU Qingfeng1;  CHEN Lei2;  XU Yunbo1;  ZHOU Yang1;  TANG Huanan1;  ZHOU Li1
1. Department of Radiation Oncology, Cancer Center (State Key Laboratory of Biotherapy), West China Hospital, Sichuan University, Chengdu 610041, China 2. Key Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu 610065, China
关键词:
立体定向放射治疗; 小野剂量学; 蒙特卡洛模拟; 综述
Keywords:
stereotactic radiotherapy small-field dosimetry Monte Carlo simulation review
分类号:
R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2020.12.001
文献标志码:
A
摘要:
小野光子束的应用在立体定向放射治疗等放疗技术中成为研究热点之一，其剂量测定的准确性受到诸多因素的限制。笔者通过查阅国内外相关研究报道，分别从小野剂量测定的辐射探测器、剂量计响应的修正因子、剂量算法计算精度比较进行了综述。探测器的灵敏体积、类型及响应修正对小野测量结果至关重要。蒙特卡洛模拟是一个研究小野剂量学极为有效的工具。通过与蒙特卡洛模拟相比较，各剂量算法的精度各有不同，介质均匀性是影响算法偏差的因素之一。对于个体化治疗计划的剂量验证，剂量精度的差异与计划靶区体积大小及加速器是否为均整模式有关。
Abstract:
Abstract: The application of small-filed photon beam has become one of the research hotspots in radiotherapy techniques such as stereotactic radiotherapy, but the accuracy of its dosimetry is limited by many factors. Based on the domestic and overseas research reports, the paper reviews those factors like radiation detectors of small-field dosimetry, correction factors for detector response and the comparison of dose accuracy among different calculation algorithms. The sensitive volume, type and correction factor of the detectors are very important to the measurement of small field. Monte Carlo simulation is an extremely effective tool for the small-field dosimetry. By a comparison based on Monte Carlo simulation, the accuracy of dose calculation among different algorithms are found different from each other, and the uniformity of the medium is one of the factors affecting the deviation of the algorithm. For the dose verification of an individualized treatment plan, the difference in dose accuracy is related to the size of planned target volume and depends on whether flattening filter has been used in the accelerator.

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备注/Memo

备注/Memo:
【收稿日期】2020-08-16 【基金项目】国家自然科学基金（11905150，11505012，81672969）；四川省科技计划资助（2018HH0099）；国际抗癌协会（UICC-TF/20/722837）；教育部科技发展中心产学研创新基金-“智融兴教”基金（2018A01019）；国家重点研发计划资助（2019YFF01014405） 【作者简介】李巧艺，技师，研究方向：医学物理与放射治疗技术，E-mail: 740771355@qq.com 【通信作者】周莉，博士，副主任技师，研究方向：放射治疗物理技术，E-mail: li.zhou@scu.edu.cn
更新日期/Last Update: 2020-12-30