[1]郭畅,沈泽天,赵本新,等.去伪影技术在头颈部肿瘤精准放疗中应用研究[J].中国医学物理学杂志,2025,42(1):7-13.[doi:DOI:10.3969/j.issn.1005-202X.2025.01.002]
　GUO Chang,SHEN Zetian,ZHAO Benxin,et al.Application of artifact removal technique in precision radiotherapy for head and neck tumors[J].Chinese Journal of Medical Physics,2025,42(1):7-13.[doi:DOI:10.3969/j.issn.1005-202X.2025.01.002]
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去伪影技术在头颈部肿瘤精准放疗中应用研究()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
42
期数:
2025年第1期
页码:
7-13
栏目:
医学放射物理
出版日期:
2025-01-19

文章信息/Info

Title:
Application of artifact removal technique in precision radiotherapy for head and neck tumors
文章编号:
1005-202X（2025）01-0007-07
作者:
郭畅1; 沈泽天1; 赵本新1; 周含1; 2
1.南京医科大学第四附属医院放疗科， 江苏 南京 211500； 2.南京大学电子科学与工程学院， 江苏 南京 210046
Author(s):
GUO Chang1;  SHEN Zetian1;  ZHAO Benxin1;  ZHOU Han1;  2
1. Department of Radiation Oncology, the Fourth Affiliated Hospital of Nanjing Medical University, Nanjing 211500, China 2. School of Electronic Science and Engineering, Nanjing University, Nanjing 210046, China
关键词:
头颈部肿瘤; CT值; 剂量; 自动勾画; 金属伪影; MAR
Keywords:
Keywords: head and neck tumor CT value irradiation dose auto-segmentation metal artifact metal artifact reducing
分类号:
R318；R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2025.01.002
文献标志码:
A
摘要:
目的：探讨Discovery RT（GE Inc）模拟定位设备去伪影技术对于器官勾画及放疗计划的影响。方法：选择2021年9月~2024年2月在南京医科大学第四附属医院接受放疗的12名携带金属假牙的头颈部肿瘤患者。使用自动勾画软件AccuContour分别对经过MAR算法处理过的CT图像和常规CT图像进行危及器官（OAR）勾画。然后比较有无金属伪影OAR轮廓的三维Dice相似性系数（DSC）、豪斯多夫距离（HD）及OARs的平均CT值。把处理过的CT图像以及原始图像传输至Monaco计划系统，对带有金属伪影的图像进行剂量计算，然后将计算好的计划映射到去除伪影后的图像上，比较OAR的剂量学差异。结果：去伪影前后喉、口腔、下颌骨的勾画HD稍高。去伪影前后的CT图像各组织平均CT值除了气管外，其他组织均无统计学差异（P>0.05），而伪影区域的口腔平均CT值两组有统计学差异（P<0.05）。去伪影前后放疗计划中各组织间的照射剂量仅有咽上缩肌具有统计学差异。各组织间的照射剂量相对差值为0~6.45%，其中差异范围浮动最大的组织为左晶状体（-2.92%±3.95%）和右晶状体（1.29%±3.35%）。结论：金属伪影对于距离伪影较近组织的OAR勾画CT值以及计划剂量影响较大，需要人工勾画的介入，其他组织几乎没有差异。
Abstract:
Abstract: Objective To explore the application effect of artifact removal technique of Discovery RT (GE Inc) in organ segmentation and radiotherapy planning. Methods Twelve patients with head and neck tumors carrying irremovable metal dentures, who received radiotherapy at the Fourth Affiliated Hospital of Nanjing Medical University from September 2021 to February 2024, were enrolled in the study. AccuContour was used to perform organs-at-risk (OAR) segmentations separately on CT image processed by metal artifact reducing algorithm and conventional CT image. Dice similarity coefficient (DSC), Hausdorff distance (HD) and the mean CT values of OAR with or without metal artifacts were compared. Both the processed CT images and original images were transferred to Monaco planning system. Dose calculation was conducted on the images with metal artifacts, and the calculated plans were mapped to the artifact-free images for analyzing the dosimetric differences of OAR. Results The HD of the throat, oral cavity and mandible were slightly higher. The mean CT values of the tissues in images before and after artifact removal were not statistically different except for the trachea (P<0.05), and the mean oral CT value at the artifact level differed significantly in two groups (P<0.05). The radiation dose of different tissues in the radiotherapy plan before and after artifact removal only showed statistical differences in the superior constrictor musde of pharynx. The percentages of irradiation dose differences for the tissues ranged from 0 to 6.45%, with the largest fluctuation in the left lens (-2.92%±3.95%) and the right lens (1.29%±3.35%). Conclusion Manual delineation is required for the tissues close to metal artifacts due to the remarkable effects on CT values and planned dose, but there is few differences in the other tissues.

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备注/Memo

备注/Memo:
【收稿日期】2024-08-21 【基金项目】南京医科大学校基金（NMUB2023038）；江苏省社会发展重点项目（BE2020685） 【作者简介】郭畅，主管技师，研究方向：肿瘤放射物理技术，E-mail: guochang94605@163.com 【通信作者】周含，高级工程师，研究方向：肿瘤放射物理技术，E-mail: hanzhou26@163.com
更新日期/Last Update: 2025-01-19