[1]杨清宇,夏兵,张硕.直肠癌术前放疗中XVMC算法和MC算法剂量差异分析[J].中国医学物理学杂志,2024,41(7):793-797.[doi:DOI:10.3969/j.issn.1005-202X.2024.07.001]
　YANG Qingyu,XIA Bing,ZHANG Shuo.Dosimetric differences between XVMC algorithm and MC algorithm in preoperative radiotherapy for rectal cancer[J].Chinese Journal of Medical Physics,2024,41(7):793-797.[doi:DOI:10.3969/j.issn.1005-202X.2024.07.001]
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直肠癌术前放疗中XVMC算法和MC算法剂量差异分析()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
41卷
期数:
2024年第7期
页码:
793-797
栏目:
医学放射物理
出版日期:
2024-07-25

文章信息/Info

Title:
Dosimetric differences between XVMC algorithm and MC algorithm in preoperative radiotherapy for rectal cancer
文章编号:
1005-202X（2024）07-0793-05
作者:
杨清宇; 夏兵; 张硕
中国医科大学附属第一医院放疗科， 辽宁 沈阳 110001
Author(s):
YANG Qingyu;  XIA Bing;  ZHANG Shuo
Department of Radiation Oncology, the First Hospital of China Medical University, Shenyang 110001, China
关键词:
直肠癌; XVMC算法; 放射治疗; MC算法; 剂量学
Keywords:
Keywords: rectal cancer X-ray voxel Monte Carlo algorithm radiotherapy Monte Carlo algorithm dosimetry
分类号:
R318；R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2024.07.001
文献标志码:
A
摘要:
目的：评估直肠癌术前放疗中，使用X射线体素蒙特卡罗（XVMC）算法与ArcherQA中蒙特卡罗（MC）算法获得的剂量分布数据的差异，为临床上XVMC算法的计划评估提供参考。方法：对10例直肠癌术前放疗的患者，采用MONACO计划系统中的XVMC算法制定计划。将计划中制定好的CT、组织结构和射野信息传入MC软件，运用MC算法进行二次剂量计算。比较XVMC算法与MC算法间靶区和各危及器官的剂量差异。结果：XVMC和MC算法计算的中心点剂量，计划靶区（PTV）的Dmin和Dmean、小肠的V40、膀胱的Dmean和V45、股骨头的Dmean差异均在2%以内。PTV、脊髓外扩和小肠三者的Dmax在两种算法的差异分别为3.43%、3.59%和3.62%；PTV的V5040差异为2.87%。结论：XVMC较MC算法低估了计划的剂量最大量，高估了靶区的处方剂量覆盖率，但两种算法之间的差异为临床可接受的范围内（5%以内），计划评估时需注意因算法所带来的剂量计算误差。
Abstract:
Abstract: Objective To evaluate the difference in dose distribution calculated using X-ray voxel Monte Carlo (XVMC) algorithm and ArcherQA Monte Carlo (MC) algorithm in preoperative radiotherapy for rectal cancer, thus providing reference for the planning and evaluation of XVMC algorithm in clinical practice. Methods For 10 patients with rectal cancer undergoing preoperative radiotherapy, the XVMC algorithm in MONACO planning system was used to develop the plan. The CT, tissue structure, and field information from the prepared plan were transmitted to Monte Carlo software, and the MC algorithm was used for the secondary dose calculation. The dose differences between XVMC algorithm and MC algorithm in the target area and organs-at-risk dose calculations were analyzed. Results The differences in Dmin and Dmean of the planning target volume (PTV), V40 of the small intestine, V45 and Dmean of the bladder, and Dmean of the femoral head calculated by XVMC and MC algorithms for isocenter dose were all within 2%. The differences in the Dmax of PTV, spinal cord expansion, and small intestine between two algorithms were 3.43%, 3.59%, and 3.62%, respectively and the difference in the V5040 of PTV was 2.87%. Conclusion XVMC algorithm underestimates the planned maximum dose and overestimates the prescription dose coverage in the target area as compared with MC algorithm, but the dosimetric differences between the two algorithms are within a clinically acceptable range (within 5%). When evaluating the plan, attention should be paid to the dose calculation errors caused by the algorithm.

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备注/Memo

备注/Memo:
【收稿日期】2024-02-02 【基金项目】国家重点研发计划（2022YFC2404704） 【作者简介】杨清宇，硕士，物理师，研究方向：放疗计划和验证，E-mail: 1183280396@qq.com 【通信作者】张硕，物理师，研究方向：放疗计划和验证，E-mail: 2446461662@qq.com
更新日期/Last Update: 2024-07-12