[1]段隆焱,蔡钢,陈毅,等. Compass在直肠癌术前调强放射治疗三维剂量验证中的应用[J].中国医学物理学杂志,2017,34(12):1200-1205.[doi:DOI:10.3969/j.issn.1005-202X.2017.12.003]
 ,,et al. Application of Compass system in three-dimensional dose verification of preoperative intensity-modulated radiotherapy plan for rectal cancer[J].Chinese Journal of Medical Physics,2017,34(12):1200-1205.[doi:DOI:10.3969/j.issn.1005-202X.2017.12.003]
点击复制

 Compass在直肠癌术前调强放射治疗三维剂量验证中的应用()
分享到:

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
34卷
期数:
2017年第12期
页码:
1200-1205
栏目:
医学放射物理
出版日期:
2017-12-20

文章信息/Info

Title:
 Application of Compass system in three-dimensional dose verification of preoperative intensity-modulated radiotherapy plan for rectal cancer
文章编号:
1005-202X(2017)12-1200-06
作者:
 段隆焱蔡钢陈毅张毅斌沈文同
 1.上海交通大学医学院附属瑞金医院放射治疗科, 上海 200025
Author(s):
 段隆焱蔡钢陈毅张毅斌沈文同
CHANG Xue, WANG Kun, ZHANG Jian, JIN Sunjun, WANG Zhipeng
关键词:
 直肠癌Compass系统调强放射治疗剂量验证术前放疗
Keywords:
rectal cancer Compass system intensity-modulated radiotherapy dose verification preoperative radiotherapy
分类号:
R815.6
DOI:
DOI:10.3969/j.issn.1005-202X.2017.12.003
文献标志码:
A
摘要:
 【摘 要】 目的:探讨Compass系统在直肠癌术前调强放射治疗三维剂量验证中的临床应用。 方法:选取10例直肠癌术前放疗患者在Pinnacle 9.10中进行优化设计,照射野采用七野扇形分布,利用Compass提供的剂量计算(CDD)和剂量重建(RDD)两种方法验证临床靶区(PTV)及危及器官的体积[γ]通过率、D95%、D50%、D2%、Dmean等参数。 结果:[γ]通过率:靶区与危及器官CDD-TPS均大于98.5%,且CDD-TPS均高于RDD-TPS。PTV和膀胱[γ]通过率差异显著(t=-2.731、2.298, P<0.05)。剂量体积差异:PTV的D2%、膀胱和右侧股骨头的Dmean剂量差异显著(t=-4.280、-2.582、-2.582, P<0.05)。同时PTV的D50%、D2%、左右侧股骨头的Dmean剂量差异CDD-TPS更大。 结论:Compass系统提供的剂量验证方法和三维剂量偏差以及[γ]通过率等剂量评估指标,能够科学合理评估直肠癌术前调强放射治疗计划,具有重要的临床意义。
Abstract:
Abstract: Objective To investigate the clinical application of Compass system in the three-dimensional (3D) dose verification of preoperative intensity-modulated radiotherapy (IMRT) plan for patients with rectal cancer. Methods Ten preoperative IMRT plans for rectal cancer were optimized with Pinncale 9.10 treatment planning system (TPS). The irradiation field in plans was seven fields showing fan-shaped distribution. Two kinds of dose verification methods in Compass system, namely dose calculation and dose reconstruction, were separately used to obtain computed dose distribution (CDD) and reconstructed dose distribution (RDD) for verifying the Gamma passing rate, D95%, D50%, D2%, and Dmean of the planning target volume (PTV) and organs-at-risk. Results The Gamma passing rates of PTV and organs-at-risk from CDD-TPS were greater than 98.5%, meanwhile, the rates from CDD-TPS were higher than those from RDD-TPS. The differences between CDD-TPS and RDD-TPS in the Gamma passing rates of PTV and bladder were statistically significant (t=2.731, 2.298; P<0.05). The D2% of PTV and the Dmean of the bladder and the right femoral head between CDD-TPS and RDD-TPS were also statistically significant (t=-4.280, -2.582, -2.582; P<0.05). Compared with RDD-TPS, CDD-TPS showed greater D50%, D2% of PTV and Dmean of the left and right femoral head. Conclusion The dose verification and evaluation methods, three-dimensional dose deviation and Gamma passing rate provided by Compass system can reasonably verify the preoperative IMRT plan for rectal cancer, with clinical significance.

相似文献/References:

[1]张武哲,陈志坚,彭 逊,等.不同角度固定野动态调强在直肠癌术前放疗中的剂量学比较[J].中国医学物理学杂志,2014,31(02):4735.[doi:10.3969/j.issn.1005-202X.2014.02.004]
[2]李忠伟,张九堂,吴智理,等.R620-ACF型腹部碳纤维托架对直肠癌调强放射治疗剂量的影响[J].中国医学物理学杂志,2014,31(05):5148.[doi:10.3969/j.issn.1005-202X.2014.05.012]
[3]吴虹,翟福山,刘明,等.应用CBCT研究膀胱体积大小对直肠癌术后放疗剂量学的影响[J].中国医学物理学杂志,2013,30(04):4253.[doi:10.3969/j.issn.1005-202X.2013.04.010]
[4]张艺宝,吴昊,李莎,等.临床前验证与几何对比分析基于图谱库的危及器官自动勾画[J].中国医学物理学杂志,2015,32(06):761.[doi:doi:10.3969/j.issn.1005-202X.2015.06.001]
 [J].Chinese Journal of Medical Physics,2015,32(12):761.[doi:doi:10.3969/j.issn.1005-202X.2015.06.001]
[5]王沛沛,刘哲铭,李彩虹,等.容积旋转调强与固定野动态调强在直肠癌新辅助放疗中的剂量学比较[J].中国医学物理学杂志,2015,32(06):901.[doi:doi:10.3969/j.issn.1005-202X.2015.06.030]
 [J].Chinese Journal of Medical Physics,2015,32(12):901.[doi:doi:10.3969/j.issn.1005-202X.2015.06.030]
[6]姚文良,许波,戚金凤,等.直肠癌术前不同照射技术剂量学比较[J].中国医学物理学杂志,2016,33(3):317.[doi:DOI:10.3969/j.issn.1005-202X.2016.03.021]
 [J].Chinese Journal of Medical Physics,2016,33(12):317.[doi:DOI:10.3969/j.issn.1005-202X.2016.03.021]
[7]王遥,霍万里,熊壮,等.TACE手术中不同站姿下铅眼镜和铅面罩对医生眼晶状体防护效果的蒙特卡洛模拟比较[J].中国医学物理学杂志,2016,33(6):553.[doi:DOI:10.3969/j.issn.1005-202X.2016.06.003]
 [J].Chinese Journal of Medical Physics,2016,33(12):553.[doi:DOI:10.3969/j.issn.1005-202X.2016.06.003]
[8]张新,谷晓芳,王培臣,等.轻离子束治疗设备注册检验关键技术问题[J].中国医学物理学杂志,2016,33(6):559.[doi:10.3969/j.issn.1005-202X.2016.06.004]
 [J].Chinese Journal of Medical Physics,2016,33(12):559.[doi:10.3969/j.issn.1005-202X.2016.06.004]
[9]江芬芬,王培,康盛伟,等. 热释光剂量片测量肺部肿瘤放疗剂量的方法[J].中国医学物理学杂志,2016,33(6):564.[doi:10.3969/j.issn.1005-202X.2016.06.005]
 [J].Chinese Journal of Medical Physics,2016,33(12):564.[doi:10.3969/j.issn.1005-202X.2016.06.005]
[10]刘洪源,彭威,杨锐,等. 锥形束CT离线校正肺癌摆位误差[J].中国医学物理学杂志,2016,33(6):573.[doi:10.3969/j.issn.1005-202X.2016.06.007]
 [J].Chinese Journal of Medical Physics,2016,33(12):573.[doi:10.3969/j.issn.1005-202X.2016.06.007]
[11]王贝,全红,邱杰,等. 容积旋转调强技术用于直肠癌时最佳机架角度设置研究[J].中国医学物理学杂志,2016,33(9):898.[doi:10.3969/j.issn.1005-202X.2016.09.006]
 [J].Chinese Journal of Medical Physics,2016,33(12):898.[doi:10.3969/j.issn.1005-202X.2016.09.006]
[12]左宇浩,杨振,周剑良,等. 基于危及器官分区约束的等效均匀剂量优化在直肠癌容积调强放疗中的应用[J].中国医学物理学杂志,2018,35(1):36.[doi:DOI:10.3969/j.issn.1005-202X.2018.01.008]
 ZUO Yuhao,YANG Zhen,ZHOU Jianliang,et al. Application of equivalent uniform dose based on organs-at-risk partition constraint in volumetric modulated arc therapy for rectal cancer[J].Chinese Journal of Medical Physics,2018,35(12):36.[doi:DOI:10.3969/j.issn.1005-202X.2018.01.008]
[13]左宇浩,杨振,周剑良,等. 基于广义等效均匀剂量优化的直肠癌计划在固定野和容积旋转调强放疗中的比较[J].中国医学物理学杂志,2018,35(2):171.[doi:DOI:10.3969/j.issn.1005-202X.2018.02.010]
 ZUO Yuhao,YANG Zhen,ZHOU Jianliang,et al. Comparison of different plans based on generalized equivalent uniform dose optimization for rectal cancer: fixed-field intensity-modulated radiotherapy vs volumetric modulated arc therapy[J].Chinese Journal of Medical Physics,2018,35(12):171.[doi:DOI:10.3969/j.issn.1005-202X.2018.02.010]
[14]刘良友,杨涛,丛小虎,等. 两套商用治疗计划系统中VMAT计划质量及其验证的对比研究[J].中国医学物理学杂志,2018,35(11):1241.[doi:DOI:10.3969/j.issn.1005-202X.2018.11.001]
 LIU Liangyou,YANG Tao,CONG Xiaohu,et al. Comparison on plan quality and dose verification of volumetric modulated arc therapy plans designed by two commercial planning systems[J].Chinese Journal of Medical Physics,2018,35(12):1241.[doi:DOI:10.3969/j.issn.1005-202X.2018.11.001]

备注/Memo

备注/Memo:
【收稿日期】2017-09-16
【基金项目】国家自然科学基金青年科学基金(81402522)
【作者简介】段隆焱,研究方向:肿瘤放射物理、图像处理,E-mail: aaronduan812@hotmail.com
更新日期/Last Update: 2017-12-20