[1]谢孟臻,吴斌,许立强,等.双层探测器光谱CT虚拟平扫中重建层厚对肝细胞癌显示的影响[J].中国医学物理学杂志,2022,39(12):1495-1501.[doi:DOI:10.3969/j.issn.1005-202X.2022.12.007]
　XIE Mengzhen,WU Bin,XU Liqiang,et al.Effect of reconstructed slice thickness on the display of hepatocellular carcinoma in virtual non-contrast scan of dual-layer detector spectral CT[J].Chinese Journal of Medical Physics,2022,39(12):1495-1501.[doi:DOI:10.3969/j.issn.1005-202X.2022.12.007]
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双层探测器光谱CT虚拟平扫中重建层厚对肝细胞癌显示的影响()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
39卷
期数:
2022年第12期
页码:
1495-1501
栏目:
医学影像物理
出版日期:
2022-12-25

文章信息/Info

Title:
Effect of reconstructed slice thickness on the display of hepatocellular carcinoma in virtual non-contrast scan of dual-layer detector spectral CT
文章编号:
1005-202X（2022）12-1495-07
作者:
谢孟臻; 吴斌; 许立强; 刘于宝; 王金电; 赵彦博; 高俊文
南方医科大学深圳医院医学影像中心， 广东 深圳 518110
Author(s):
XIE Mengzhen;  WU Bin;  XU Liqiang;  LIU Yubao;  WANG Jindian;  ZHAO Yanbo;  GAO Junwen
Medical Imaging Center, Shenzhen Hospital of Southern Medical University, Shenzhen 518110, China
关键词:
肝细胞癌; 双层探测器光谱CT; 虚拟平扫; 辐射剂量
Keywords:
Keywords: hepatocellular carcinoma dual-detector spectral CT virtual non-contrast scan radiation dose
分类号:
R816.1
DOI:
DOI:10.3969/j.issn.1005-202X.2022.12.007
文献标志码:
A
摘要:
目的：探讨双层探测器光谱CT虚拟平扫（VNC）对肝细胞癌（HCC）显示的最佳层厚。方法：回顾性分析73例HCC患者腹部CT扫描的影像资料，分别获得5、3、1 mm不同层厚的常规平扫（TNC）、动脉期VNC（VNC-a）图像和门静脉期VNC（VNC-p）图像。比较3种不同层厚TNC、VNC-a和VNC-p图像的CT值、信噪比（SNR）、对比噪声比（CNR）和噪声（SD）。通过Bland-Altman plot散点图分析TNC图像和VNC图像的CT值一致性；采用5分法评价图像质量。结果：3种层厚VNC-a图像、VNC-p图像与TNC图像相比，SNR升高，SD降低，差异有统计学意义（P<0.05），CT值和CNR的差异无统计学意义（P>0.05）；组内两两比较，5和3 mm层厚VNC-p图像比VNC-a图像SD更低，SNR更高（P<0.05），1 mm图像VNC-p与VNC-a图像SD和SNR差异无统计学意义（P>0.05）。5和3 mm层厚VNC-a图像和VNC-p图像与TNC图像的CT值一致性良好，其中3 mm VNC-p图像LOA界限外的数据点比例最低（1.4%），与TNC的一致性最好。3个层厚的3种图像中，1 mm VNC-p图像主观评分最高。1 mm层厚中，VNC-p图像主观评分显著高于TNC图像和VNC-a图像（P<0.05）；VNC-p图像中，1 mm图像主观评分显著高于5、3 mm图像（P<0.05）。取消TNC直接增强扫描可降低34.57%的辐射剂量。结论：双层探测器光谱CT中VNC的层厚设置对该技术的应用存在影响。3 mm VNC-p图像CT值一致性最高，SD最低，SNR最高，可用作观察客观测量指标，1 mm VNC-p图像对病灶轮廓和细节显示最佳，可用作主观评价。
Abstract:
Abstract: Objective To explore the optimal slice thickness for virtual non-contrast scan (VNC) of dual-layer detector spectral CT of hepatocellular carcinoma (HCC). Methods The imaging data of abdominal CT scan of 73 HCC patients were analyzed retrospectively. The true non-contrast (TNC), arterial VNC (VNC-a) and portal VNC (VNC-p) images with the slice thickness of 5, 3 and 1 mm were evaluated and compared in terms of CT number, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and noise (SD). The consistency of the CT number between TNC image and VNC image was analyzed using Bland Altman plot scatter diagram, and the image quality was evaluated using 5-point method. Results Compared with TNC images, VNC-a and VNC-p images of different slice thicknesses had higher SNR and lower SD (P<0.05), but there was no statistical difference in CT number and CNR (P>0.05). The pairwise comparison within the group revealed that VNC-p images with the slice thickness of 5 and 3 mm had lower SD and higher SNR than VNC-a images (P<0.05), and that for the slice thickness of 1 mm, SD and SNR were close in VNC-p image and VNC-a image (P>0.05). For the slice thicknesses of 5 and 3 mm, the CT numbers of VNC-a image, VNC-p images and TNC images were in good consistency, of which 3 mm VNC-p image has the lowest proportion of data points outside the LOA (1.4%) and had the best consistency with TNC. The subjective score of 1 mm VNC-p images was the highest among all images. For 1 mm slice thickness, the subjective score of VNC-p image was significantly higher than TNC image and VNC-a image (P<0.05) for VNC-p images, the image with 1 mm slice thickness significantly higher than those with 5 and 3 mm slice thicknesses (P<0.05). Cancellation of TNC and direct enhanced scan reduced the radiation dose by 34.57%. Conclusion The application of VNC of double-layer detector spectral CT is affected by slice thickness. VNC-p image with the slice thickness of 3 mm has the highest consistency in CT number, the lowest SD and the highest SNR, which can be used for objective measurement and VNC-p image with the slice thickness of 1 mm shows the best outline and details of the lesion, and can be used for subjective evaluation.

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备注/Memo

备注/Memo:
【收稿日期】2022-08-12 【基金项目】国家高性能医疗器械创新中心开放基金（NMED2021MS-01-003）；深圳市科技创新委员会基础研究项目（JCYJ2021032412540301） 【作者简介】谢孟臻，初级技师，研究方向：CT影像技术，E-mail: xiemengzhen95@163.com 【通信作者】吴斌，硕士，副主任技师，研究方向：CT、MRI影像技术，E-mail: wubin3835@163.com
更新日期/Last Update: 2022-12-23