[1]谢孟臻,吴斌,刘于宝,等.超低对比剂剂量和流率在头颈部CT血管造影中的应用[J].中国医学物理学杂志,2022,39(9):1128-1132.[doi:DOI:10.3969/j.issn.1005-202X.2022.09.012]
　XIE Mengzhen,WU Bin,LIU Yubao,et al.Application of ultra-low dose and flow-rate contrast injection protocol in head and neck CT angiography[J].Chinese Journal of Medical Physics,2022,39(9):1128-1132.[doi:DOI:10.3969/j.issn.1005-202X.2022.09.012]
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超低对比剂剂量和流率在头颈部CT血管造影中的应用()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
39卷
期数:
2022年第9期
页码:
1128-1132
栏目:
医学影像物理
出版日期:
2022-11-02

文章信息/Info

Title:
Application of ultra-low dose and flow-rate contrast injection protocol in head and neck CT angiography
文章编号:
1005-202X（2022）09-1128-05
作者:
谢孟臻1; 吴斌1; 刘于宝1; 侯严振1; 杜 牧1; 贺雄军2
1.南方医科大学深圳医院医学影像中心， 广东 深圳 518110； 2.南方医科大学深圳医院神经内科， 广东 深圳 518110
Author(s):
XIE Mengzhen1;  WU Bin1;  LIU Yubao1;  HOU Yanzhen1;  DU Mu1;  HE Xiongjun2
1. Medical Imaging Center, Shenzhen Hospital of Southern Medical University, Shenzhen 518110, China 2. Department of Neurology, Shenzhen Hospital of Southern Medical University, Shenzhen 518110, China
关键词:
双层探测器光谱CT; 头颈CTA; 单能谱成像; 低剂量; 对比剂
Keywords:
Keywords: dual-layer spectral detector CT head and neck CT angiography monoenergetic spectral imaging low dose contrast agent
分类号:
R816.1
DOI:
DOI:10.3969/j.issn.1005-202X.2022.09.012
文献标志码:
A
摘要:
目的：探讨双层探测器光谱CT在对比剂低耐受度患者头颈部CT血管造影（CTA）检查中应用超低对比剂剂量和流率扫描的优势。方法：收集对比剂低耐受度患者40例（观察组），对比剂用量20 mL，流率2 mL/s，所得图像行40 keV单能谱重建；选取同期普通患者40例（对照组），对比剂用量50 mL，流率5 mL/s；两组患者体质量均在70 kg以下。比较两组患者图像的主观评分、CT值、信号噪声比（SNR）、对比噪声比（CNR）和辐射剂量。结果：两组动脉显影图像主观评分比较差异无统计学意义（P>0.05）；在主动脉弓水平，观察组图像CT值、SNR和CNR均显著高于对照组（P<0.05）；在双侧颈总动脉分叉处及双侧大脑中动脉M1段，两组图像CT值比较差异无统计学意义（P>0.05），但观察组图像SNR和CNR值均显著高于对照组（P<0.05）；观察组和对照组间容积CT剂量指数、剂量长度乘积、有效辐射剂量比较差异均无统计学意义（P>0.05）。结论：双层探测器光谱CT在低耐受度患者头颈CTA检查中应用超低对比剂剂量和流率的扫描方案可以满足诊断需求，降低了对比剂肾病、对比剂外渗等副作用风险，且未增加辐射剂量。
Abstract:
Abstract: Objective To explore the advantages of dual-layer spectral detector CT using ultra-low dose and flow-rate contrast injection protocol in head and neck CT angiography (CTA) for patients with low tolerance to contrast agent. Methods Forty patients with low tolerance to contrast agent were enrolled in observation group. The contrast agent of 20 mL and flow rate of 2 mL/s were used in observation group, and the obtained images were reconstructed by 40 keV monoenergetic spectrum. Meanwhile, 40 general patients in the same period were enrolled in control group. The dosage of contrast agent in control group was 50 mL, and the flow rate was 5 mL/s. The weights of patients in both groups were below 70 kg. The subjective image score, CT value, signal-noise ratio (SNR), contrast to noise ratio (CNR) and radiation dose were compared between two groups. Results There was no statistical difference in the subjective image scores of arterial imaging between two groups (P>0.05). At the level of aortic arch, the CT value, SNR and CNR of observation group were significantly higher than those of control group (P<0.05). In bilateral common carotid artery bifurcation and M1 segment of bilateral middle cerebral artery, no significant difference was found in CT value between two groups (P>0.05), but SNR and CNR of observation group were significantly higher than those of control group (P<0.05). The differences in volume CT dose index, dose length product,and effective radiation dose between observation group and control group were trivial (P>0.05). Conclusion The application of dual-layer spectral detector CT using ultra-low dose and flow-rate contrast injection protocol in head and neck CTA for patients with low tolerance can meet the diagnostic needs, reduce the risk of adverse reactions such as contrast nephropathy and contrast extravasation, and do not increase radiation dose.

相似文献/References:

[1]谢孟臻,吴斌,许立强,等.双层探测器光谱CT虚拟平扫中重建层厚对肝细胞癌显示的影响[J].中国医学物理学杂志,2022,39(12):1495.[doi:DOI:10.3969/j.issn.1005-202X.2022.12.007]
　XIE Mengzhen,WU Bin,XU Liqiang,et al.Effect of reconstructed slice thickness on the display of hepatocellular carcinoma in virtual non-contrast scan of dual-layer detector spectral CT[J].Chinese Journal of Medical Physics,2022,39(9):1495.[doi:DOI:10.3969/j.issn.1005-202X.2022.12.007]

备注/Memo

备注/Memo:
【收稿日期】2022-03-18 【基金项目】深圳医疗卫生“三名工程”高层次医学团队项目（SZSM201812047）；深圳市宝安区科创局项目（2020JD453） 【作者简介】谢孟臻，初级技师，研究方向：CT影像技术，E-mail: xiemengzhen95@163.com 【通信作者】吴斌，硕士，副主任技师，研究方向：CT、MRI影像技术，E-mail: wubin3835@163.com
更新日期/Last Update: 2022-09-27