[1]刘佳琳,王帅,张立新.经颅磁刺激促进脑卒中功能恢复的作用机制[J].中国医学物理学杂志,2021,38(10):1279-1284.[doi:DOI:10.3969/j.issn.1005-202X.2021.10.017]
 LIU Jialin,WANG Shuai,ZHANG Lixin.Mechanism of transcranial magnetic stimulation in promoting functional recovery in stroke[J].Chinese Journal of Medical Physics,2021,38(10):1279-1284.[doi:DOI:10.3969/j.issn.1005-202X.2021.10.017]
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经颅磁刺激促进脑卒中功能恢复的作用机制()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
38卷
期数:
2021年第10期
页码:
1279-1284
栏目:
医学生物物理
出版日期:
2021-10-27

文章信息/Info

Title:
Mechanism of transcranial magnetic stimulation in promoting functional recovery in stroke
文章编号:
1005-202X(2021)10-1279-06
作者:
刘佳琳1王帅2张立新1
1.中国医科大学附属盛京医院康复中心, 辽宁 沈阳110000; 2.中山大学附属第一医院康复医学科, 广东 广州 510000
Author(s):
LIU Jialin1 WANG Shuai2 ZHANG Lixin1
1. Rehabilitation Center, Shengjing Hospital of China Medical University, Shenyang 110000, China 2. Department of Rehabilitation Medicine, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510000, China
关键词:
经颅磁刺激脑卒中运动功能综述
Keywords:
Keywords: transcranial magnetic stimulation stroke motor function review
分类号:
R318;R743.3
DOI:
DOI:10.3969/j.issn.1005-202X.2021.10.017
文献标志码:
A
摘要:
近年来国内脑卒中发病率逐年上升,经颅磁刺激以其无痛、无创的治疗优势应用于脑卒中患者的康复治疗中,但目前其促进脑卒中后运动功能恢复的作用机制尚不完全明确,本文从其调节刺激部位脑血流量、调节大脑皮层兴奋性、调节大脑半球双相平衡模型、诱导长时程效应、调节突触可塑性和促进轴突再生、调节神经递质和激活神经通路、改善神经元微环境和调节干细胞增殖分化的研究做一综述,以期为临床治疗提供参考。
Abstract:
Abstract: In recent years, the incidence of stroke has been increasing year by year in our country. Transcranial magnetic stimulation with the advantages of painless and non-invasive has been applied in the rehabilitation of patients with stroke. However, the mechanism of its promotion of motor function recovery after stroke still remains unclear. Herein the mechanisms of transcranial magnetic stimulation in promoting functional recovery in stroke are reviewed from several aspects, including the regulation of cerebral blood flow at the stimulation site, the regulation of excitability of the cerebral cortex, the regulation of biphasic equilibrium model of the cerebral hemisphere, the induction of long-term effects, the regulation of synaptic plasticity for promoting axon regeneration, the regulation of neurotransmitters for activating neural pathways, the improvement of neuronal microenvironment, and the regulation of stem cell proliferation and differentiation, thereby providing reference for clinical treatment.

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备注/Memo

备注/Memo:
【收稿日期】2021-04-19 【基金项目】国家自然科学基金青年基金(81101462);辽宁省自然科学基金(201602875, 2019-KF-01-06);辽宁省公益科学基金(2016003001);2019年中国医科大学校培育学科建设项目(112-3110119071) 【作者简介】刘佳琳,硕士,研究方向:磁刺激的康复应用,E-mail:18842463503@163.com 【通信作者】张立新,主任医师,研究方向:磁刺激的康复应用,E-mail:zhanglx@sj-hospital.org
更新日期/Last Update: 2021-10-29