[1]李耀志,谢艺才.磁共振颅颈一体化高分辨血管壁成像评价颈动脉斑块负荷与脑卒中的关系[J].中国医学物理学杂志,2022,39(3):328-332.[doi:DOI:10.3969/j.issn.1005-202X.2022.03.012]
　LI Yaozhi,XIE Yicai.Relationship between carotid plaques burden and stroke: an evaluation by high-resolution craniocervical MR vessel wall imaging[J].Chinese Journal of Medical Physics,2022,39(3):328-332.[doi:DOI:10.3969/j.issn.1005-202X.2022.03.012]
点击复制

磁共振颅颈一体化高分辨血管壁成像评价颈动脉斑块负荷与脑卒中的关系()
分享到：

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
39卷
期数:
2022年第3期
页码:
328-332
栏目:
医学影像物理
出版日期:
2022-03-28

文章信息/Info

Title:
Relationship between carotid plaques burden and stroke: an evaluation by high-resolution craniocervical MR vessel wall imaging
文章编号:
1005-202X（2022）03-0328-05
作者:
李耀志; 谢艺才
梧州市红十字会医院放射科， 广西 梧州 543002
Author(s):
LI Yaozhi;  XIE Yicai
Department of Radiology, Wuzhou Red Cross Hospital, Wuzhou 543002, China
关键词:
磁共振; 颅颈一体化; 血管壁成像; 颈动脉斑块负荷; 脑卒中; 预测价值
Keywords:
Keywords: magnetic resonance imaging craniocervical integration vessel wall imaging carotid plaques burden stroke predictive value
分类号:
R445.2；R743.9
DOI:
DOI:10.3969/j.issn.1005-202X.2022.03.012
文献标志码:
A
摘要:
目的：探讨磁共振（MRI）颅颈一体化高分辨血管壁成像评价颈动脉斑块负荷与脑卒中的关系。方法：100例缺血性脑卒中患者为研究对象，并以50例无症状的高危人群为对照组，均行MRI平扫及增强头颅一体化血管壁成像扫描，观察指标包括患者缺血侧及非缺血侧的颈动脉血管壁参数［管腔面积（LA）、血管总面积（TVA）、管壁面积（WA）、管壁标准化指数（NWI）］；根据研究组患者是否存在脑组织不可逆死亡将其分为预后较好组及预后不良组，比较两组缺血侧颈动脉管壁参数，分析其对患者预后的评估价值；分析颈动脉管壁参数与美国国立卫生研究院卒中量表（NIHSS）的相关性；对照组均随访2年，根据脑卒中发生情况将其分为脑卒中组及正常组，比较两组颈动脉管壁参数，分析其对发生缺血性脑卒中的预测价值。结果：研究组缺血侧TVA、WA及NWI值大于非缺血侧，LA值小于非缺血侧（P<0.05）；预后不良组TVA、WA及NWI值大于预后较好组，LA值小于预后较好组（P<0.05）；颈动脉管壁参数联合检测评估患者预后的AUC大于0.75；患者LA值与NIHSS评分呈负相关（P<0.05），TVA、WA及NWI值与NIHSS评分无相关性（P>0.05）。脑卒中组TVA、WA及NWI值大于正常组，LA值小于正常组（P<0.05）；颈动脉管壁参数联合检测评估高危人群缺血性脑卒中发病的AUC大于0.75。结论：TVA、WA、NWI及LA值联合检测对缺血性脑卒中患者预后具有评估价值，对高危人群脑卒中发病具有预测价值，且LA值与神经功能损伤程度相关。
Abstract:
Abstract: Objective To explore the relationship between carotid plaques burden and stroke by high-resolution craniocervical MR vessel wall imaging (HR-VWI). Methods A total of 100 patients with ischemic stroke were enrolled as study group, and another 50 asymptomatic patients at high risk as control group. All subjects underwent MRI plain scan and enhanced HR-VWI. Carotid wall parameters, including lumen area (LA), total vascular area (TVA), wall area (WA), normalized wall index (NWI), were measured on the ischemic and non-ischemic sides. According to whether there was irreversible death of brain tissues, patients in study group were further divided into good prognosis group and poor prognosis group, and the carotid wall parameters on ischemic side were compared between the two groups for analyzing their evaluation value for prognosis. The correlation between carotid wall parameters and score of National Institutes of Health Stroke Scale (NIHSS) was also analyzed. The patients in control group were followed-up for 2 years, and then further grouped into stroke group and normal group according to whether they had a stroke. The carotid wall parameters were compared between stroke group and normal group for analyzing their predictive value for ischemic stroke. Results In study group, the TVA, WA and NWI on ischemic side were greater than those on non-ischemic side, while LA was lower than that on non-ischemic side (P<0.05). The TVA, WA and NWI in poor prognosis group were greater than those in good prognosis group, while LA was lower than that in good prognosis group (P<0.05). The AUC of the combination of carotid wall parameters for assessing prognosis was greater than 0.75. LA was negatively correlated with NIHSS score (P<0.05), but TVA, WA and NWI were not correlated with NIHSS score (P>0.05). Compared with normal group, stroke group had larger TVA, WA and NWI, but lower LA (P<0.05). The AUC of the combination of carotid wall parameters for assessing the onset of ischemic stroke in high-risk groups was greater than 0.75. Conclusion The combination of TVA, WA, NWI and LA is of evaluation value for the prognosis of patients with ischemic stroke, and is of predictive value for stroke onset in high-risk groups. Moreover, LA is related to the severity of neurological damage.

相似文献/References:

[1]李金泽,李 华,喻 罡,等.基于大脑形态学和SVM的孤独症自动识别[J].中国医学物理学杂志,2014,31(06):5338.[doi:10.3969/j.issn.1005-202X.2014.06.026]
[2]黄磊,付峰,邓官华,等.磁共振拉莫尔频率下生物组织介电参数温度特性[J].中国医学物理学杂志,2015,32(06):798.[doi:doi:10.3969/j.issn.1005-202X.2015.06.009]
[3]何汶静,许玉霞,黄正宽.基于Computer Simulation Technology 的磁共振射频线圈模拟与设计[J].中国医学物理学杂志,2017,34(1):44.[doi:10.3969/j.issn.1005-202X.2017.01.009]
　[J].Chinese Journal of Medical Physics,2017,34(3):44.[doi:10.3969/j.issn.1005-202X.2017.01.009]
[4]喻伟,马永红,徐胜,等. 植入金标患者做MRI检查的安全性[J].中国医学物理学杂志,2017,34(4):377.[doi:DOI:10.3969/j.issn.1005-202X.2017.04.011]
[5]张振显,宋鹏. 脊柱结核与脊柱转移瘤的磁共振弥散加权成像影像学特征分析[J].中国医学物理学杂志,2018,35(6):676.[doi:DOI:10.3969/j.issn.1005-202X.2018.06.011]
　ZHANG Zhenxian,SONG Peng. Imaging features of magnetic resonance imaging-diffusion weighted imaging on spinal tuberculosis and spinal metastatic tumor[J].Chinese Journal of Medical Physics,2018,35(3):676.[doi:DOI:10.3969/j.issn.1005-202X.2018.06.011]
[6]王海东. Siemens Skyra3.0 T新型磁共振成像设备故障维修与保养[J].中国医学物理学杂志,2018,35(10):1217.[doi:DOI:10.3969/j.issn.1005-202X.2018.10.021]
　WANG Haidong. Maintenance and repair of Siemens Skyra3.0 T magnetic resonance imaging apparatus[J].Chinese Journal of Medical Physics,2018,35(3):1217.[doi:DOI:10.3969/j.issn.1005-202X.2018.10.021]
[7]杨华,龚明福,邹利光,等. CL-PEG-MnFe2O4纳米胶束介导的肿瘤微血管和微淋巴管双重靶向MR成像[J].中国医学物理学杂志,2019,36(9):1034.[doi:DOI:10.3969/j.issn.1005-202X.2019.09.008]
　YANG Hua,GONG Mingfu,ZOU Liguang,et al. Magnetic resonance imaging of angiogenesis and lymphangiogenesis in tumor using dual-targeted CL-PEG-MnFe2O4 nanomicelles[J].Chinese Journal of Medical Physics,2019,36(3):1034.[doi:DOI:10.3969/j.issn.1005-202X.2019.09.008]
[8]朱熹,叶靖,王志军,等. 并行采集技术在头颅磁共振中产生伪影的原因及处理方法[J].中国医学物理学杂志,2019,36(9):1039.[doi:DOI:10.3969/j.issn.1005-202X.2019.09.009]
　ZHU Xi,YE Jing,WANG Zhijun,et al. Causes and solutions of artifacts caused by array spatial sensitivity encoding technique in brain MRI[J].Chinese Journal of Medical Physics,2019,36(3):1039.[doi:DOI:10.3969/j.issn.1005-202X.2019.09.009]
[9]林恒山,林增如,李燕燕,等.磁共振扩散张量成像序列对脊髓型颈椎病的诊断价值[J].中国医学物理学杂志,2019,36(11):1291.[doi:DOI:10.3969/j.issn.1005-202X.2019.11.009]
　LIN Hengshan,LIN Zengru,et al.Diagnostic value of diffusion tensor magnetic resonance imaging sequence in cervical spondylotic myelopathy[J].Chinese Journal of Medical Physics,2019,36(3):1291.[doi:DOI:10.3969/j.issn.1005-202X.2019.11.009]
[10]杨镜全,高明勇,周新韩,等.FIESTA和SSFSE序列在胎盘植入磁共振成像技术中的应用[J].中国医学物理学杂志,2019,36(12):1444.[doi:DOI:10.3969/j.issn.1005-202X.2019.12.015]
　YANG Jingquan,GAO Mingyong,ZHOU Xinhan,et al.Applications of FIESTA and SSFSE sequences in magnetic resonance imaging of placenta increta[J].Chinese Journal of Medical Physics,2019,36(3):1444.[doi:DOI:10.3969/j.issn.1005-202X.2019.12.015]

备注/Memo

备注/Memo:
【收稿日期】2021-08-21 【基金项目】广西壮族自治区卫生和计划生育委员会科研课题（Z20170643） 【作者简介】李耀志，副主任医师，研究方向：放射学诊断，E-mail: shdyy0604@qq.com
更新日期/Last Update: 2022-03-28