[1]赵洪明,彭红梅,张东威,等.锁骨下动脉、颈总动脉和椎动脉分叉处血流动力学数值模拟[J].中国医学物理学杂志,2021,38(9):1151-1187.[doi:10.3969/j.issn.1005-202X.2021.09.019]
ZHAO Hongming,PENG Hongmei,ZHANG Dongwei,et al.Numerical simulation for hemodynamics at the bifurcations of subclavian artery, commoncarotid artery and vertebral artery[J].Chinese Journal of Medical Physics,2021,38(9):1151-1187.[doi:10.3969/j.issn.1005-202X.2021.09.019]
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锁骨下动脉、颈总动脉和椎动脉分叉处血流动力学数值模拟(
)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- 卷:
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38卷
- 期数:
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2021年第9期
- 页码:
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1151-1187
- 栏目:
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生物材料与力学
- 出版日期:
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2021-09-26
文章信息/Info
- Title:
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Numerical simulation for hemodynamics at the bifurcations of subclavian artery, common
carotid artery and vertebral artery
- 文章编号:
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1005-202X（2021）09-1154-07
- 作者:
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赵洪明1; 彭红梅1; 张东威2; 陈阳1
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1. 内蒙古民族大学数理学院，内蒙古通辽028043；2. 内蒙古民族大学附属医院神经内科，内蒙古通辽028000
- Author(s):
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ZHAO Hongming1; PENG Hongmei1; ZHANG Dongwei2; CHEN Yang1
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1. College of Mathematics and Physics, Inner Mongolia Minzu University, Tongliao 028043, China 2. Department of Neurology,
Affiliated Hospital of Inner Mongolia Minzu University, Tongliao 028000, China
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- 关键词:
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锁骨下动脉; 颈总动脉; 椎动脉; 医学建模; 血流动力学; 计算流体力学
- Keywords:
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subclavian artery common carotid artery vertebral artery medical modeling hemodynamics computational
fluid dynamics
- 分类号:
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R318.01；O357.1
- DOI:
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10.3969/j.issn.1005-202X.2021.09.019
- 文献标志码:
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A
- 摘要:
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目的：探讨锁骨下动脉、颈总动脉和椎动脉分叉处的血流动力学特性，分析该处发生血管狭窄引起大脑供血不足的
血流动力学原因。方法：采用内蒙古民族大学附属医院神经内科提供的CT数据，应用医学建模软件MIMICS20.0将患者
二维CT数据进行三维血管重建，经过网格划分及边界条件设置后导入计算流体力学软件FLUENT14.5中。计算和分析
不同血液入口速度的锁骨下动脉、颈总动脉和椎动脉分叉处的血流动力学特性。结果：在血液入口速度不同的情况下，锁
骨下动脉、颈总动脉和椎动脉分叉处的血液流场分布、血液压力分布和血管壁面切应力分布有显著变化。在血液入口速
度增大时，锁骨下动脉分叉处和颈总动脉分叉处的血液流速快、血管壁压力大，颈总动脉内侧血管壁面切应力大，但锁骨
下动脉分叉处和颈总动脉分叉处血管壁面切应力数值和变化幅度小，属于低切应力区。结论：通过血流动力学数值模拟
研究，分析锁骨下动脉、颈总动脉和椎动脉分叉处易发生粥样斑块病变导致大脑供血不足的血流动力学原因。
- Abstract:
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Objective To explore the hemodynamic characteristics at the bifurcations of subclavian artery, common carotid
artery and vertebral artery, and to analyze the hemodynamic reason for the insufficiency of the cerebral blood supply caused
by vascular stenosis occurred here. Methods The CT data provided by Department of Neurology, Affiliated Hospital of Inner
Mongolia Minzu University were used in the study. The medical modeling software MIMICS 20.0 was used to reconstruct
the two-dimensional CT date into three-dimensional blood vessel, and after grid division and boundary condition setting, it
was imported into computational fluid dynamics software FLUENT14.5. The hemodynamic characteristics at the
bifurcations of subclavian artery, common carotid artery and vertebral artery with different blood inlet velocities were
calculated and analyzed. Results The distributions of blood flow field, blood pressure and wall shear stress at the bifurcations
of subclavian artery, common carotid artery and vertebral artery changed significantly when the blood inlet velocity was
different. With the increasing blood inlet velocity, the blood flow velocities at subclavian artery bifurcation and common
carotid artery bifurcation were faster, and the vessel wall pressure at the bifurcations was increased, and the shear stress of the
medial common carotid artery was larger, but the shear stress and change range of the vessel wall at subclavian artery
bifurcation and common carotid artery bifurcation were small, indicating that subclavian artery bifurcation and common
carotid artery bifurcation still belonged to the low shear stress area. Conclusion The analysis on the hemodynamic reasons
for the insufficiency of the cerebral blood supply caused by atherosclerotic plaque at the bifurcation of subclavian artery,
common carotid artery and vertebral artery bifurcate are realized through the hemodynamic numerical simulation.
备注/Memo
- 备注/Memo:
-
【收稿日期】2021-04-20
【基金项目】国家自然科学基金（11362015, 81641127）；内蒙古自治区
自然科学基金（2013MS0113, 2018LH01005）
【作者简介】赵洪明，在读硕士，研究方向：计算生物流体力学，E-mail:
1126010996@qq.com
更新日期/Last Update:
2021-09-27