[1]曹潘潘,彭海燕,蒙万里,等.Tomotherapy MVCT不同配准方式对头颈部摆位的影响[J].中国医学物理学杂志,2021,38(7):798-803.[doi:DOI:10.3969/j.issn.1005-202X.2021.07.002]
　CAO Panpan,PENG Haiyan,MENG Wanli,et al.Effects of different registration methods for Tomotherapy MVCT on head and neck positioning[J].Chinese Journal of Medical Physics,2021,38(7):798-803.[doi:DOI:10.3969/j.issn.1005-202X.2021.07.002]
点击复制

Tomotherapy MVCT不同配准方式对头颈部摆位的影响()
分享到：

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
38卷
期数:
2021年第7期
页码:
798-803
栏目:
医学放射物理
出版日期:
2021-07-26

文章信息/Info

Title:
Effects of different registration methods for Tomotherapy MVCT on head and neck positioning
文章编号:
1005-202X（2021）07-0798-06
作者:
曹潘潘; 彭海燕; 蒙万里; 李师; 何阳; 罗焕丽; 毛开金; 颜廷璨; 王希夷; 冉雪琪; 靳富
重庆大学附属肿瘤医院/重庆市肿瘤医院/重庆市肿瘤研究所放疗科， 重庆 400030
Author(s):
CAO Panpan;  PENG Haiyan;  MENG Wanli;  LI Shi;  HE Yang;  LUO Huanli;  MAO Kaijin;  YAN Tingcan;  WANG Xiyi;  RAN Xueqi;  JIN Fu
Department of Radiation Oncology, Chongqing University Cancer Hospital/Chongqing Cancer Hospital/Chongqing Cancer Institute, Chongqing 400030, China
关键词:
螺旋断层放射治疗; 兆伏级CT; 重建层厚; 图像配准
Keywords:
Keywords: Tomotherapy megavoltage computed tomography reconstructed slice thickness image registration
分类号:
R318；R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2021.07.002
文献标志码:
A
摘要:
目的：评估螺旋断层放射治疗（Tomotherapy, TOMO）兆伏级CT（MVCT）不同配准方式对头颈部摆位的影响。方法：首先基于室内激光和体表标记对头颈部模体进行摆位，行MVCT图像引导并自动配准，误差修正后将其作为参考图像。随后进行单、双及3方向移床（-5~5 mm，步长1 mm），分别用Bone、Bone and Tissue和Full Image方式进行配准，最后记录左右（X）、头脚（Y）、腹背（Z）的摆位误差。结果：不同配准方式下，Bone的摆位误差最小。在Fine 1 mm模式下，Bone和Bone and Tissue配准存在显著差异，摆位误差分别为0.5（0.3, 0.8） mm和0.6（0.4, 0.8） mm；在Fine 2 mm模式下，Bone和Bone and Tissue配准同样存在显著差异，摆位误差分别为0.4（0.3, 0.7） mm和0.5（0.4, 0.8） mm。在Normal 2 mm和Coarse 3 mm模式下，3种配准方式均存在显著差异（P<0.05）。在Fine 2 mm和Normal 2 mm模式下，3种图像配准均无差异（P>0.05）。不同配准方式下，Y方向相关性最低。CTV-PTV外放Margin值在Bone配准方式下，X、Y、Z 3个方向分别为2.1、2.8、2.2 mm；Bone and Tissue配准方式下，X、Y、Z 3个方向分别为2.1、2.7、2.2 mm；Full Image配准方式下，X、Y、Z 3个方向分别为2.2、3.0、2.2 mm。结论：综合3种模式相同的扫描长度、扫描时间和剂量考虑，在TOMO临床治疗头颈部患者时，可选择Normal模式，优先选择Bone配准方式。
Abstract:
Abstract: Objective To evaluate the effects of different registration methods for Tomotherapy megavoltage computed tomography (MVCT) on head and neck positioning. Methods The head-and-neck phantom was positioned based on indoor laser and body surface markers and then received MVCT scan. After automatic image registration and error correction, the obtained image was used as the reference. Subsequently, the treatment couch was artificially moved in single, 2 and 3 directions (from -5 to 5 mm, with a step length of 1 mm). Three different kinds of methods, namely Bone, Bone and Tissue, Full Image, were adopted for image registration. The positioning errors in left-right (X), superior-inferior (Y) and anterior-posterior (Z) directions were recorded. Results When adopting Bone for image registration, the positioning errors were the smallest. In Fine 1 mm and 2 mm modes, there were significant variations for the positioning errors between registration using Bone and registration using Bone and Tissue, and the positioning errors were 0.5 (0.3, 0.8) mm and 0.6 (0.4, 0.8) mm for Fine 1 mm mode, and 0.4 (0.3, 0.7) mm and 0.5 (0.4, 0.8) mm for Fine 2 mm mode. In Normal 2 mm and Coarse 3 mm modes, there were significant differences among 3 registration methods (P<0.05) while in Fine 2 mm and Normal 2 mm modes, no significant difference was found (P>0.05). Whatever registration method was adopted, the correlation in Y direction was the lowest. The CTV-PTV Margin in X, Y and Z directions were 2.1, 2.8, 2.2 mm for Bone, 2.1, 2.7, 2.2 mm for Bone and Tissue, and 2.2, 3.0, 2.2 mm for Full Image, respectively. Conclusion Based on the comprehensive consideration on 3 modes, with the same scan length, scan time and dose, Normal mode combined with Bone is preferentially recommended in clinical Tomotherapy for patients with head and neck cancer.

相似文献/References:

[1]张晋建,黎 静,文 婷,等.Arc CHECK在乳腺癌螺旋断层放疗计划剂量验证中的应用[J].中国医学物理学杂志,2015,32(02):244.[doi:10.3969/j.issn.1005-202X.2015.02.021]
[2]王小深,戴相昆,陈高翔,等. 评估辐射自显影胶片非均匀性及其对螺旋断层放射治疗剂量验证的影响[J].中国医学物理学杂志,2017,34(4):340.[doi:DOI:10.3969/j.issn.1005-202X.2017.04.004]
[3]沈奕晨,王为,张松方,等. 乳腺癌螺旋断层放射治疗与调强放射治疗的剂量学研究与临床剂量实测比较[J].中国医学物理学杂志,2018,35(3):269.[doi:DOI:10.3969/j.issn.1005-202X.2018.03.005]
　SHEN Yichen,WANG Wei,ZHANG Songfang,et al. Dosimetry study and measured dose comparison of Tomotherapy and intensity-modulated radiotherapy for breast cancer[J].Chinese Journal of Medical Physics,2018,35(7):269.[doi:DOI:10.3969/j.issn.1005-202X.2018.03.005]
[4]蔡汉飞,方美芳,徐露,等. Gafchromic EBT3胶片在螺旋断层放射治疗计划验证中的应用[J].中国医学物理学杂志,2018,35(11):1257.[doi:DOI:10.3969/j.issn.1005-202X.2018.11.004]
　CAI Hanfei,FANG Meifang,XU Lu,et al. Application of Gafchromic EBT3 film in the verification of TomoTherapy plan[J].Chinese Journal of Medical Physics,2018,35(7):1257.[doi:DOI:10.3969/j.issn.1005-202X.2018.11.004]
[5]刘娟,李双双,高山宝,等. 宫颈癌螺旋断层放疗与静态调强技术的剂量学比较[J].中国医学物理学杂志,2019,36(1):23.[doi:DOI:10.3969/j.issn.1005-202X.2019.01.005]
　LIU Juan,LI Shuangshuang,GAO Shanbao,et al. Dosimetric comparison of helical tomotherapy versus fixed-field intensity-modulated radiotherapy for cervical cancer[J].Chinese Journal of Medical Physics,2019,36(7):23.[doi:DOI:10.3969/j.issn.1005-202X.2019.01.005]
[6]张晋建,李志强,文婷,等.肺癌螺旋断层放疗计划设计中应用Block减少肺低剂量区的研究[J].中国医学物理学杂志,2019,36(2):152.[doi:DOI:10.3969/j.issn.1005-202X.2019.02.006]
　ZHANG Jinjian,LI Zhiqiang,WEN Ting,et al. Applying Block to reduce low-dose volume of lungs in helical tomotherapy of lung cancer[J].Chinese Journal of Medical Physics,2019,36(7):152.[doi:DOI:10.3969/j.issn.1005-202X.2019.02.006]
[7]闫冰,吴爱东,张洪波,等. 肝细胞癌共面和非共面容积旋转调强放疗与螺旋断层放疗的剂量学研究[J].中国医学物理学杂志,2019,36(8):877.[doi:DOI:10.3969/j.issn.1005-202X.2019.08.003]
　YAN Bing,WU Aidong,ZHANG Hongbo,et al. Dosimetric study on coplanar and noncoplanar volumetric modulated arc therapy and helical tomotherapy for hepatocellular carcinoma[J].Chinese Journal of Medical Physics,2019,36(7):877.[doi:DOI:10.3969/j.issn.1005-202X.2019.08.003]
[8]徐伟,杨涛,解传滨,等. 质子点扫描技术与光子Tomotherapy在前列腺癌应用中的剂量学比较[J].中国医学物理学杂志,2019,36(10):1129.[doi:DOI:10.3969/j.issn.1005-202X.2019.10.003]
　XU Wei,YANG Tao,XIE Chuanbin,et al. Dosimetric comparison between single spot scanning of proton therapy and tomotherapy for prostate cancer[J].Chinese Journal of Medical Physics,2019,36(7):1129.[doi:DOI:10.3969/j.issn.1005-202X.2019.10.003]
[9]方春锋,解传滨,徐寿平,等.不同铅门模式下高危分期前列腺癌螺旋断层放射治疗剂量学比较[J].中国医学物理学杂志,2020,37(2):138.[doi:DOI:10.3969/j.issn.1005-202X.2020.02.002]
　FANG Chunfeng,XIE Chuanbin,et al.Dosimetric study of helical tomotherapy for high-risk prostate cancer under different jaw modes[J].Chinese Journal of Medical Physics,2020,37(7):138.[doi:DOI:10.3969/j.issn.1005-202X.2020.02.002]
[10]王海洋,皮一飞,韩滨,等.空气压缩设备故障引起的螺旋断层放射治疗患者计划验证通过率偏低的案例分析[J].中国医学物理学杂志,2021,38(1):1.[doi:DOI:10.3969/j.issn.1005-202X.2021.01.001]
　WANG Haiyang,PI Yifei,HAN Bin,et al.A case analysis of low pass rate of helical tomotherapy patient plan verification caused by air compression equipment failure[J].Chinese Journal of Medical Physics,2021,38(7):1.[doi:DOI:10.3969/j.issn.1005-202X.2021.01.001]

备注/Memo

备注/Memo:
【收稿日期】2021-02-11 【基金项目】国家自然科学基金（11575038, 11805025, 81972857） 【作者简介】曹潘潘，初级技师，研究方向：放疗技术，E-mail: p18623193021@163.com 【通信作者】靳富，博士，高级工程师，E-mail: jfazj@126.com
更新日期/Last Update: 2021-07-26