[1]田龙,闫洁诚,李明辉,等.利用多次采集计划CT和锥形束CT评价前列腺癌靶区运动相关性[J].中国医学物理学杂志,2021,38(2):172-177.[doi:DOI:10.3969/j.issn.1005-202X.2021.02.009]
　TIAN Long,YAN Jiecheng,LI Minghui,et al.Evaluating the correlation between pre- and in-treatment target displacements in prostate cancer radiotherapy by multiple acquisition planning CT and cone-beam CT[J].Chinese Journal of Medical Physics,2021,38(2):172-177.[doi:DOI:10.3969/j.issn.1005-202X.2021.02.009]
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利用多次采集计划CT和锥形束CT评价前列腺癌靶区运动相关性()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
38卷
期数:
2021年第2期
页码:
172-177
栏目:
医学放射物理
出版日期:
2021-02-02

文章信息/Info

Title:
Evaluating the correlation between pre- and in-treatment target displacements in prostate cancer radiotherapy by multiple acquisition planning CT and cone-beam CT
文章编号:
1005-202X（2021）02-0172-06
作者:
田龙1; 闫洁诚1; 李明辉2; 胡逸民2; 张遵浩3
1.河北北方学院附属第一医院放疗科， 河北 张家口 075000； 2.中国医学科学院北京协和医科大学肿瘤医院肿瘤研究所放疗科， 北京 100021； 3.河北医科大学第一医院放疗科， 河北 石家庄 050000
Author(s):
TIAN Long1;  YAN Jiecheng1;  LI Minghui2;  HU Yimin2;  ZHANG Zunhao3
1. Department of Radiotherapy, the First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, China 2. Department of Radiotherapy, Cancer Institute, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China 3. Department of Radiotherapy, the First Hospital of Hebei Medical University, Shijiazhuang 050000, China
关键词:
前列腺癌; 多次采集计划CT; 锥形束CT; 内植标记物; 相关性
Keywords:
Keywords: prostate cancer multiple acquisition planning CT cone-beam CT implanted marker correlation
分类号:
R812
DOI:
DOI:10.3969/j.issn.1005-202X.2021.02.009
文献标志码:
A
摘要:
目的：利用多次采集计划CT（MAPCT）和锥形束CT获取前列腺癌患者靶区治疗前和治疗中位移数据，评价治疗前、治疗中靶区各向运动之间相关性，从而为优化靶区计划设计提供数据支持。方法：筛选12例前列腺癌患者，于靶区内植金标记物，接受3次治疗前MAPCT扫描和10次治疗中锥形束CT扫描，利用两种扫描数据评价治疗前、治疗中靶区各向运动相关性。结果：治疗前、治疗中位移在左右、头脚方向上相关性系数R分别为0.559、-0.326，中度，弱相关，结果不具有统计学意义；前后方向R为0.883，强相关，结果具有统计学意义。结论：可以利用治疗前MAPCT预估前后方向上治疗中靶区位移量，从而优化前列腺癌放疗计划。
Abstract:
Abstract: Objective To evaluate the correlation between the dimensional target displacements before and during treatment for prostate cancer using target displacement data obtained by multiple acquisition planning CT and cone-beam CT, thereby providing some data support for the optimization of treatment planning. Methods Gold implants were implanted in the target areas of 12 prostate cancer patients. Each patient underwent 3 pre-treatment multiple acquisition planning CT scans and 10 in-treatment cone-beam CT scans. The correlation of pre- and in-treatment dimensional target displacements was evaluated by the data obtained in scanning. Results The correlation coefficient R of the displacements in left-right and superior-inferior directions before and during treatment was 0.559 and -0.326, respectively, which indicated moderate and week correlations, without statistical significance. However, the correlation in anterior-posterior direction was relatively strong and statistically significant, with the coefficient R of 0.883. Conclusion Pre-treatment multiple acquisition planning CT can be used to predict the in-treatment target displacements in anterior-posterior direction, thereby optimizing the radiotherapy plan of prostate cancer.

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备注/Memo

备注/Memo:
【收稿日期】2020-05-02 【基金项目】张家口市重点研发计划（1921002B） 【作者简介】田龙，硕士，主管技师，主要从事放射治疗研究，E-mail: 1277473912@qq.com
更新日期/Last Update: 2021-02-02