[1]赵永亮,吴建亭,金建华,等.宫颈癌术后放疗不同体位膀胱充盈程度对危及器官的影响[J].中国医学物理学杂志,2021,38(1):11-14.[doi:DOI:10.3969/j.issn.1005-202X.2021.01.003]
　ZHAO Yongliang,WU Jianting,JIN Jianhua,et al.Effect of bladder filling degree and different positions on OARs in post-operation radiotherapy for cervical cancer[J].Chinese Journal of Medical Physics,2021,38(1):11-14.[doi:DOI:10.3969/j.issn.1005-202X.2021.01.003]
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宫颈癌术后放疗不同体位膀胱充盈程度对危及器官的影响()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
38卷
期数:
2021年第1期
页码:
11-14
栏目:
医学放射物理
出版日期:
2021-01-29

文章信息/Info

Title:
Effect of bladder filling degree and different positions on OARs in post-operation radiotherapy for cervical cancer
文章编号:
1005-202X（2021）01-0011-04
作者:
赵永亮; 吴建亭; 金建华; 储开岳
南通市肿瘤医院放疗科， 江苏 南通 226361
Author(s):
ZHAO Yongliang;  WU Jianting;  JIN Jianhua;  CHU kaiyue
Department of Radiotherapy, Nantong Tumor Hospital, Nantong 226361, China
关键词:
宫颈癌; 膀胱; 容积调强弧形治疗; 仰卧位; 俯卧位; 危及器官
Keywords:
Keywords: cervical cancer bladder VMAT supine position prone position organs at risk
分类号:
R737.33；R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2021.01.003
文献标志码:
A
摘要:
目的：探讨宫颈癌术后患者不同体位固定下膀胱充盈对宫颈癌危及器官的剂量学影响。方法：回顾性分析南通市肿瘤医院已经接受容积调强弧形治疗技术放疗的宫颈癌术后患者，通过放疗治疗计划系统对膀胱体积进行测量，分别筛选出行两种固定方法（仰卧位组与俯卧位组）的患者共86例，每组43例。分析两组患者剂量体积直方图中膀胱、小肠、直肠、乙状结肠、结肠的V30、V40及平均受量（Dmean）。通过表格对采集数据生成趋势图并读出每条趋势线R平方值。结果：两组患者的膀胱、小肠、直肠、乙状结肠、结肠的Dmean、V30无统计学意义（P>0.05），俯卧位下膀胱、直肠、乙状结肠、结肠较仰卧位的V40有统计学意义（P<0.05）。俯卧位下膀胱充盈程度与各危及器官的V30、V40、Dmean对应数据拟合度较高，随着膀胱容量的增加，各危及器官的受量降低。结论：宫颈癌治疗行俯卧位对于危及器官的保护优于仰卧位，膀胱体积的增大会使各危及器官照射剂量降低。
Abstract:
Abstract: Objective To investigate the dosimetric effects of different bladder filling degree with different fixed positions on the organs at risk (OARs) of cervical cancer. Methods 86 cervical cancer patients who had accepted Volumetric Modulated Arc Therapy (VMAT) in Nantong City were retrospectively analyzed. Their bladders volume was measured by Treatment Planning System (TPS). The 86 patients were divided into two groups according to their different fixed positions (supine position and prone position), with each group 43 patients. V30, V40 and mean Dose Volume (Dmean) of the bladder, small intestine, rectum, sigmoid colon and colon in Dose Volume Histogram (DVH) were compared between the two groups of patients. A trend chart was generated from the collected data and the R square value of each trend line was read out. Results The differences in Dmean and V30 of bladder, small intestine, rectum, sigmoid colon and colon between the two groups were not statistically significant (P>0.05), while the differences in V40 of bladder, rectum, sigmoid colon and colon between the two groups were statistically significant (P<0.05). In prone position, the degree of bladder filling was proved highly fitted to the corresponding data of V30, V40 and Dmean of each organ at risk: with the increase of bladder volume, the corresponding data of each organ at risk decreased. Conclusion Prone position is better than supine position in the protection of organs at risk, and with the increase of bladder volume, the exposure dose for organs at risk will decrease.

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备注/Memo

备注/Memo:
【收稿日期】2020-07-11 【基金项目】南通市科技计划项目（GJZ17043） 【作者简介】赵永亮，助理工程师，主要研究方向：妇科肿瘤，E-mail: zyl3315230@126.com 【通信作者】储开岳，主任技师，主要研究方向：放疗物理工作，E-mail: Chu_ky@163.com
更新日期/Last Update: 2021-01-29