[1]王警建,李娜,王龙龙,等. 能谱CT鉴别肺部炎性病变和肺癌的临床价值[J].中国医学物理学杂志,2018,35(10):1164-1168.[doi:DOI:10.3969/j.issn.1005-202X.2018.10.010]
　WANG Jingjian,LI Na,WANG Longlong,et al. Clinical value of energy spectrum CT for the differential diagnosis of pulmonary inflammatory lesion and lung cancer[J].Chinese Journal of Medical Physics,2018,35(10):1164-1168.[doi:DOI:10.3969/j.issn.1005-202X.2018.10.010]
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 能谱CT鉴别肺部炎性病变和肺癌的临床价值()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
35卷
期数:
2018年第10期
页码:
1164-1168
栏目:
医学影像物理
出版日期:
2018-10-25

文章信息/Info

Title:
 Clinical value of energy spectrum CT for the differential diagnosis of pulmonary inflammatory lesion and lung cancer
文章编号:
1005-202X（2018）10-1164-05
作者:
 王警建; 李娜; 王龙龙; 高延忠
 西安市第九医院CT-MR室， 陕西 西安 710054
Author(s):
 WANG Jingjian;  LI Na;  WANG Longlong;  GAO Yanzhong
 CT-MR Room, Ninth Hospital of Xi’an, Xi’an 710054, China
关键词:
 ; 能谱CT; 肺癌; 肺部炎性病变; 鉴别; 诊断; 碘浓度
Keywords:
 ; Keywords: energy spectrum CT;  lung cancer;  pulmonary inflammatory lesion;  differential diagnosis;  iodine concentration
分类号:
R445.3
DOI:
DOI:10.3969/j.issn.1005-202X.2018.10.010
文献标志码:
A
摘要:
 目的：观察能谱CT对肺部炎性病变和肺癌的鉴别价值。 方法：选取85例肺部占位病变患者，均采取能谱CT平扫、肺动脉期和主动脉期能谱扫描。根据病理结果将患者分为肺癌组与炎性病变组，比较两组IC肺动脉期、IC主动脉期、dIC肺动脉期、dIC主动脉期、dCT肺动脉期、dCT主动脉期、有效原子序数，并做受试者工作特性曲线判断不同参数的诊断效能。 结果：85例患者中肺癌患者52例，炎性病变患者33例。肺癌患者的IC肺动脉期、IC主动脉期、dIC肺动脉期、dIC主动脉期、dCT肺动脉期显著低于炎性病变患者（P<0.05）。肺炎患者与炎性病变患者的dCT主动脉期与有效原子序数无统计学意义（P>0.05）。dIC肺动脉期对肺癌与炎性病变的鉴别价值最大，敏感度高达0.966，同时标准误差仅0.027。 结论：能谱CT的IC值与CT值有利于炎性病灶与肺癌的鉴别，其中dIC肺动脉期的鉴别价值最大。
Abstract:
 Abstract: Objective To evaluate the value of energy spectrum computed tomography (CT) in differentially diagnosing lung inflammatory lesion and lung cancer. Methods A total of 85 patients with pulmonary space-occupying lesions were selected. All patients underwent energy spectrum CT plain scans, pulmonary artery and aortic scans. According to the pathological results, the patients were divided into lung cancer group and inflammatory lesion group. The iodine concentration (IC) of pulmonary arterial phase, IC of aortic phase, net increase of IC (dIC) of pulmonary artery phase, dIC of aortic phase, net increase of CT value (dCT) of pulmonary artery phase, dCT of aortic phase, and effective atomic number were compared between two groups. The diagnostic performance of different parameters was determined by receiver operating characteristic curve. Results Of the 85 patients, 52 patients were diagnosed with lung cancer and 33 were diagnosed with inflammatory lesions. IC of pulmonary arterial phase, IC of aortic phase, dIC of pulmonary artery phase, dIC of aortic phase, and dCT of pulmonary artery phase were significantly lower in patients with lung cancer as compared with those with inflammatory lesions (P<0.05). No statistical significance was found in dCT of aortic phase and effective atomic number between patients with pneumonia and those with inflammatory lesions (P>0.05). The dIC of pulmonary arterial phase had the greatest value in distinguishing lung cancer from inflammatory lesions, with a sensitivity of 0.966 and a standard error of only 0.027. Conclusion The IC value and CT value of energy spectrum CT are helpful for the differential diagnosis of inflammatory lesion and lung cancer, among which the dIC of pulmonary arterial phase has the greatest discriminative value.

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备注/Memo

备注/Memo:
 【收稿日期】2018-04-24
【作者简介】王警建，副主任医师，E-mail: gg29018327@qq.com
【通信作者】高延忠，主治医师，E-mail: 308074959@qq.com
更新日期/Last Update: 2018-10-23