[1]邓亚军,韩蕾,解琪琪,等. 能谱CT与DXA测量骨密度准确性的比较研究[J].中国医学物理学杂志,2019,36(2):194-198.[doi:DOI:10.3969/j.issn.1005-202X.2019.02.014]
　DENG Yajun,HAN Lei,et al. Comparison of the accuracy of bone mineral density measurement by spectral CT vs DXA[J].Chinese Journal of Medical Physics,2019,36(2):194-198.[doi:DOI:10.3969/j.issn.1005-202X.2019.02.014]
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 能谱CT与DXA测量骨密度准确性的比较研究()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
36卷
期数:
2019年第2期
页码:
194-198
栏目:
医学影像物理
出版日期:
2019-02-25

文章信息/Info

Title:
 Comparison of the accuracy of bone mineral density measurement by spectral CT vs DXA
文章编号:
1005-202X（2019）02-0194-05
作者:
 邓亚军1; 2; 韩蕾3; 解琪琪1; 2; 李文洲1; 2; 史卫东1; 2; 马靖林2; 潘云燕3; 康学文1; 汪静1; 2
 1.兰州大学第二医院骨科， 甘肃 兰州 730030； 2.甘肃省骨关节疾病研究重点实验室， 甘肃 兰州 730030； 3.兰州大学第二医院放射科， 甘肃 兰州 730030
Author(s):
 DENG Yajun1;  2;  HAN Lei3;  XIE Qiqi1;  2;  LI Wenzhou1;  2;  SHI Weidong1;  2;  MA Jinglin2;  PAN Yunyan3;  KANG Xuewen1;  WANG Jing1;  2
 1. Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou 730030, China; 2. Key Laboratory of Bone and Joint Diseases of Gansu Province, Lanzhou 730030, China; 3. Department of Radiology, Lanzhou University Second Hospital, Lanzhou 730030, China
关键词:
 ; 能谱CT; 双能X线骨密度仪; 骨密度; 腰椎体; 灰重密度
Keywords:
 ; Keywords: spectral computed tomography;  dual-energy X-ray absorptiometry;  bone density;  lumbar vertebrae;  ash density
分类号:
R318.01；R445.3
DOI:
DOI:10.3969/j.issn.1005-202X.2019.02.014
文献标志码:
A
摘要:
 目的：以羊腰椎体骨煅烧后的灰重密度为标准，比较能谱CT与双能X线骨密度仪（DXA）测量椎体骨密度（BMD）的准确性，探讨能谱CT对BMD的测量价值。 方法：选取36节新鲜市售羊腰椎椎体作为研究对象，清除椎体周围软组织及其附件后，分别采用能谱CT与DXA测量BMD，然后煅烧椎体得到灰重密度。将两种方法测量所得BMD值与灰重密度值进行比较，同时分析两种方法测量所得BMD值与灰重密度值的相关性；最后将能谱CT测得BMD的偏离度与DXA测得体积BMD的偏离度进行比较。 结果：能谱CT、DXA测得BMD值与灰重密度值差异有统计学意义（P<0.05）；相关性分析可得，能谱CT与DXA测得BMD值与灰重密度值均有显著相关性（P<0.05），但能谱CT相关性更高；能谱CT测得BMD的偏离度（平均值为0.288）低于DXA测得BMD的偏离度（平均值为0.372）（P<0.05）。结论：能谱CT测量椎体BMD值更接近灰重密度值，准确性及相关性均优于DXA测量方法，能够更好、更精确地反映BMD变化。
Abstract:
Abstract: Objective With the ash density of sheep lumbar vertebrae as the standard, to compare the accuracy of spectral computed tomography (CT) and dual-energy X-ray absorptiometry (DXA) for vertebral bone mineral density (BMD) measurement, and to investigate the value of spectral CT in BMD measurement. Methods A total of 36 freshly prepared sheep lumbar vertebrae were selected as the research object. After removing soft tissue around the vertebral body and its attachments, BMD was measured by spectral CT and DXA, and the vertebral body was calcined to obtain the ash density. The BMD values measured by the two methods were compared with ash density, and the correlations between the measured BMD values and ash density were analyzed. Finally, the deviation of BMD measured by energy spectrum CT was compared with the deviation of BMD measured by DXA. Results The difference between measured BMD and ash density was statistically significant (P<0.05). There was a significant correlation between measured BMD and ash density (P<0.05), but the correlation of ash density and BMD measured with spectral CT was higher. The mean deviation of BMD measured by spectral CT was lower than the mean deviation of BMD measured by DXA (0.288 vs 0.372, P<0.05). Conclusion The BMD measured by spectral CT is closer to ash density. Spectral CT is superior to DXA in BMD measurement accuracy and the correction with ash density, which indicates that spectral CT can reflect the changes of BMD more accurately.

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备注/Memo

备注/Memo:
【收稿日期】2018-10-12
【基金项目】国家自然科学基金（81371230）；兰州大学第二医院院内博士科研基金（ynbskyjj2015-1-01）
【作者简介】邓亚军，硕士研究生，研究方向：骨质疏松、骨生物力学，E-mail: 157342993@qq.com；韩蕾，硕士研究生，研究方向：神经影像学，E-mail: 2199390253@qq.com（邓亚军和韩蕾为共同第一作者）
【通信作者】汪静，博士，副主任医师，副教授，研究方向：骨质疏松、疼痛，E-mail: wang_jing@lzu.edu.cn
更新日期/Last Update: 2019-02-26