[1]李雅宁,陆世培,彭应林,等. BodyFIX联合腹压板在肝癌大剂量放射治疗中的应用[J].中国医学物理学杂志,2018,35(3):265-268.[doi:DOI:10.3969/j.issn.1005-202X.2018.03.004]
　LI Yaning,LU Shipei,PENG Yinglin,et al. Application of BodyFIX combined with abdominal pressure plate in stereotactic body radiotherapy for liver cancer[J].Chinese Journal of Medical Physics,2018,35(3):265-268.[doi:DOI:10.3969/j.issn.1005-202X.2018.03.004]
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 BodyFIX联合腹压板在肝癌大剂量放射治疗中的应用()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
35卷
期数:
2018年第3期
页码:
265-268
栏目:
医学放射物理
出版日期:
2018-03-20

文章信息/Info

Title:
 Application of BodyFIX combined with abdominal pressure plate in stereotactic body radiotherapy for liver cancer
文章编号:
R816.5
作者:
 李雅宁; 陆世培; 彭应林; 邵剑辉; 杨鑫; 林承光
 中山大学肿瘤防治中心放疗科， 广东 广州 510060
Author(s):
 LI Yaning;  LU Shipei;  PENG Yinglin;  SHAO Jianhui;  YANG Xin;  LIN Chengguang
 Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China
关键词:
 ; 肝癌; 大剂量放射治疗; BodyFIX联合腹压板; 呼吸运动; 摆位误差
Keywords:
 ; liver cancer;  stereotactic body radiotherapy;  BodyFIX combined with abdominal pressure plate;  breathing movement;  setup errors
分类号:
1005-202X（2018）03-0265-04
DOI:
DOI:10.3969/j.issn.1005-202X.2018.03.004
文献标志码:
A
摘要:
 目的：利用BodyFIX联合腹压板这一固定装置，通过抑制患者呼吸幅度，对使用BodyFIX联合腹压板和普通真空袋两组病人的摆位误差进行分析比较，评价BodyFIX联合腹压板这一装置的优缺点及其用于肝癌大剂量放射治疗的临床意义。 方法：选择20例原发性肝癌患者（BodyFIX联合腹压板和普通真空袋组各10例），采用立体定向放射治疗，分割剂量6.5 Gy/次，照射次数均为6次，隔日1次。所有患者每次治疗前均行锥形束CT扫描，记录并分析两组摆位误差大小。 结果：普通真空袋组病人在X（左右）、Y（上下）、Z（前后）3个方向上的线性误差为（0.28±3.19）、（-2.22±5.75）、（-0.66±3.85） mm，对应外放边界MPTV为8.06、13.92、9.78 mm；而使用BodyFIX联合腹压板组病人为（2.14±2.61）、（-1.94±3.78）、（0.22±2.50） mm，对应MPTV为6.57、7.57、5.98 mm。线性误差比较得出P值在X（左右）、Y（上下）、Z（前后）3个方向上分别为0.480、0.003、0.001，差异在Y和Z方向上有统计学意义。 结论：BodyFIX联合腹压板这一固定装置与普通真空袋相比，其优势在于可限制患者呼吸运动幅度，减小摆位误差，缩小靶区外放边界，对增加分次放疗剂量，提高肝癌放疗疗效有着重要的临床应用价值。
Abstract:
 Objective To compare the setup errors between two groups of liver cancer patients, namely one group treated with BodyFIX combined with abdominal pressure plate and the other one treated with vacuum bag, evaluate the advantages and disadvantages of BodyFIX combined with abdominal pressure plate, and discuss its clinical significance in stereotactic body radiotherapy (SBRT) for liver cancer. Methods Twenty patients with primary hepatic cancer were selected in this study. Ten patients were treated with BodyFIX combined with abdominal pressure plates and the other ten were treated with vacuum bags. All patients received SBRT, with 6.5 Gy/fraction, once every other day, and totally for six times. Cone beam computed tomography was performed before each treatment for the patients. The setup errors in the two groups were recorded and analyzed. Results In the group treated with vacuum bags, the linear errors in X (left-right), Y (superior-inferior) and Z (anterior-posterior) directions were (0.28±3.19), (-2.22±5.75) and (-0.66±3.85) mm, respectively, and the corresponding MPTV were 8.06, 13.92 and 9.78 mm, respectively. The linear errors of the group treated with BodyFIX combined with abdominal pressure plate in X, Y and Z directions were (2.14±2.61), (-1.94±3.78) and (0.22±2.50) mm, respectively, and the corresponding MPTV were 6.57, 7.57 and 5.98 mm, respectively. The comparison of linear errors revealed that P values in X, Y and Z directions were 0.480, 0.003 and 0.001, respectively, with statistically significant differences in Y and Z directions. Conclusion Compared to vacuum bags, BodyFIX combined with abdominal pressure plate can not only restrain the amplitude of breathing movement and reduce setup errors, but also decrease MPTV and increase fractional dose. BodyFIX combined with abdominal pressure plate is of great value in improving the therapeutic effect of radiotherapy for liver cancer.

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备注/Memo

备注/Memo:
 【收稿日期】2017-11-17
【基金项目】广东省自然科学基金（2017A030310217）；广东省科技计划项目（2015B020214002）；广州市计划项目（201710010162）； “医学信息分析及肿瘤诊疗湖北省重点实验室”开放课题（PJS140011504）
【作者简介】李雅宁，硕士研究生，技师，研究方向：放射治疗技术，E-mail: liyn@sysucc.org.cn
【通信作者】林承光，硕士研究生，主任技师，研究方向：放疗实施过程中的质量控制，E-mail: linchg@sysucc.org.cn；杨鑫，博士研究生，硕士生导师，助理研究员，研究方向：医学物理、生物医学工程、放疗质控质保，E-mail: yangxin@sysucc.org.cn
更新日期/Last Update: 2018-03-21