[1]魏夏平,苏洁洪,李琳,等.基于RGSC系统的左乳腺癌深吸气屏气放疗的应用及评估[J].中国医学物理学杂志,2023,40(8):933-937.[doi:DOI:10.3969/j.issn.1005-202X.2023.08.002]
 WEI Xiaping,SU Jiehong,LI Lin,et al.Application and evaluation of DIBH radiotherapy using RGSC for left-sided breast cancer[J].Chinese Journal of Medical Physics,2023,40(8):933-937.[doi:DOI:10.3969/j.issn.1005-202X.2023.08.002]
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基于RGSC系统的左乳腺癌深吸气屏气放疗的应用及评估()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
40卷
期数:
2023年第8期
页码:
933-937
栏目:
医学放射物理
出版日期:
2023-09-01

文章信息/Info

Title:
Application and evaluation of DIBH radiotherapy using RGSC for left-sided breast cancer
文章编号:
1005-202X(2023)08-0933-05
作者:
魏夏平1苏洁洪1李琳1安世霞1董彦鑫1黄小伟2刘叶明1黄明超1
1.广州中医药大学金沙洲医院肿瘤放射治疗中心, 广东 广州 510168; 2.东莞理工学院科学技术处, 广东 东莞 523808
Author(s):
WEI Xiaping1 SU Jiehong1 LI Lin1 AN Shixia1 DONG Yanxin1 HUANG Xiaowei2LIU Yeming1 HUANG Mingchao1
1. Department of Radiation Oncology, Jinshazhou Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510168, China 2. Department of Science and Technology, Dongguan University of Technology, Dongguan 523808, China
关键词:
乳腺癌容积旋转调强放疗呼吸门控深吸气屏气
Keywords:
Keywords: breast cancer volumetric modulated arc therapy respiratory gating deep inspiration breath hold
分类号:
R815.6;R737.9
DOI:
DOI:10.3969/j.issn.1005-202X.2023.08.002
文献标志码:
A
摘要:
目的:分析心脏和肺的受照剂量、治疗时间和摆位精度评估呼吸门控扫描器系统(RGSC)引导实现左乳腺癌术后深吸气屏气(DIBH)放疗的临床价值。方法:分别选择20例使用RGSC实现左乳腺癌术后DIBH容积调强弧形放疗的病例和20例左乳腺癌术后自由呼吸(FB)放疗的病例,两组病例的靶区都仅包含胸壁区和锁骨区。获取心脏V20、Dmean和肺V20、V10、V5、Dmean;分析靶区配准结果,记录每次治疗时间。结果:DIBH和FB放疗的心脏V20分别是2.36%±2.16%、7.26%±3.66%(P<0.01),心脏Dmean分别是(3.52±1.10) Gy、(6.56±1.59) Gy(P<0.01)。左肺V20、V10、V5、Dmean分别是18.56%±4.51% vs 23.51%±4.37%(P=0.03)、30.48%±4.99% vs 37.99%±5.13%(P<0.01)、45.95%±5.81% vs 52.08%±12.74%(P=0.02)、(10.57±1.86) Gy vs (12.43±1.66) Gy(P=0.01);右肺V5、Dmean分别是7.82%±3.59% vs 18.41%±11.44%(P<0.01)、(1.97±0.36) Gy vs(3.08±1.12) Gy(P<0.01)。DIBH和FB放疗的治疗时间为181.00(151.00, 229.00) s,70.2(69.60, 70.20) s(P<0.01)。CBCT图像进行6维配准后,在X、Y、Z平移方向和Rx、Rz旋转方向,DIBH放疗的配准误差小于FB放疗,在Ry方向差异没有统计学意义(P>0.05)。结论:基于RGSC系统实施左乳腺癌术后DIBH放疗可以实现较好的治疗精度,降低肺和心脏的剂量,但明显增加治疗时间。
Abstract:
Abstract: Objective To evaluate the clinical value of RGSC-guided deep inspiration breath hold (DIBH) radiotherapy following surgery for left-sided breast cancer by analyzing the exposure doses to heart and lung, treatment duration, and positioning accuracy. Methods After surgery for left-sided breast cancer, 20 cases receiving RGSC-guided DIBH volumetric modulated arc therapy and 20 cases treated with FB radiotherapy were enrolled, and the target areas contained only the chest wall and the clavicle. The V20, Dmean of the heart, and the V20, V10, V5, Dmean of the lung were obtained the target registration results were analyzed and the duration of each treatment was recorded. Results The V20 and Dmean of the heart in DIBH radiotherapy and FB radiotherapy were 2.36%±2.16% vs 7.26%±3.66% (P<0.01), and (3.52±1.10) Gy vs (6.56±1.59) Gy (P<0.01). The V20, V10, V5 and Dmean of the left lung in the two groups were 18.56%±4.51% vs 23.51%±4.37% (P=0.03), 30.48%±4.99% vs 37.99%±5.13% (P<0.01), 45.95%±5.81% vs 52.08%±12.74% (P=0.02), (10.57±1.86) Gy vs (12.43±1.66) Gy (P=0.01), respectively. The V5 and Dmean of the right lung were 7.82%±3.59% vs 18.41%±11.44% (P<0.01) and (1.97±0.36) Gy vs (3.08±1.12) Gy (P<0.01). The duration of DIBH radiotherapy and FB radiotherapy were 181.00 (151.00, 229.00) s and 70.20 (69.60, 70.20) s (P<0.01). After six-dimensional registration of CBCT images, the registration errors of DIBH radiotherapy were less than those of FB radiotherapy in the X, Y, Z, Rx, Rz directions, but not in the Ry direction (P>0.05). Conclusion RGSC-guided DIBH radiotherapy following surgery for left-sided breast cancer can achieve higher treatment accuracy than FB therapy, and reduce the doses exposed to the lung and heart, but increases treatment duration.

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备注/Memo

备注/Memo:
【收稿日期】2023-02-03 【基金项目】国家自然科学青年基金(12004410) 【作者简介】魏夏平,硕士,研究方向:肿瘤放射物理,E-mail: wei-xia-ping@163.com 【通信作者】苏洁洪,工程师,研究方向:肿瘤放射物理,E-mail: 573921373@qq.com
更新日期/Last Update: 2023-09-06