[1]王雁南,周俊林,刘建莉,等.多排螺旋CT低剂量扫描高分辨率重建在新型冠状病毒肺炎筛查中的应用[J].中国医学物理学杂志,2021,38(4):456-460.[doi:DOI:10.3969/j.issn.1005-202X.2021.04.012]
　WANG Yannan,,et al.Application of low-dose multidetector CT scan and high-resolution reconstruction in COVID-19 pneumonia screening[J].Chinese Journal of Medical Physics,2021,38(4):456-460.[doi:DOI:10.3969/j.issn.1005-202X.2021.04.012]
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多排螺旋CT低剂量扫描高分辨率重建在新型冠状病毒肺炎筛查中的应用()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
38卷
期数:
2021年第4期
页码:
456-460
栏目:
医学影像物理
出版日期:
2021-04-29

文章信息/Info

Title:
Application of low-dose multidetector CT scan and high-resolution reconstruction in COVID-19 pneumonia screening
文章编号:
1005-202X（2021）04-0456-05
作者:
王雁南1; 2; 3; 周俊林2; 3; 刘建莉2; 3; 那飞扬4; 周晟1; 5
1.甘肃中医药大学第一临床医学院， 甘肃 兰州 730000； 2.兰州大学第二医院放射科， 甘肃 兰州 730000； 3.甘肃省医学影像重点实验室， 甘肃 兰州 730000； 4.甘肃省妇幼保健院过敏反应科， 甘肃 兰州 730000； 5.甘肃省中医院放射科， 甘肃 兰州 730000
Author(s):
WANG Yannan1;  2;  3;  ZHOU Junlin2;  3;  LIU Jianli2;  3;  NA Feiyang4;  ZHOU Sheng1;  5
1. First Clinical Medical School, Gansu University of Chinese Medicine, Lanzhou 730000, China 2. Department of Radiology, Lanzhou University Second Hospital, Lanzhou 730000, China 3. Key Laboratory of Medical Imaging in Gansu Province, Lanzhou 730000, China 4. Allergy Department, Gansu Provincial Maternity and Child-care Hospital, Lanzhou 730000, China 5. Department of Radiology, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730000, China
关键词:
多排螺旋CT; 低剂量; 高分辨率重建; 新型冠状病毒肺炎
Keywords:
Keywords: multidetector computed tomography low-dose high-resolution reconstruction COVID-19 pneumonia
分类号:
R563.1；R816.4
DOI:
DOI:10.3969/j.issn.1005-202X.2021.04.012
文献标志码:
A
摘要:
目的：探讨多排螺旋CT（MDCT）低剂量扫描高分辨率重建在新型冠状病毒肺炎（COVID-19）筛查中的应用价值。方法：选取2020年2月1日~3月1日间就诊的66例疑似COVID-19肺炎患者作为研究对象，将66例患者随机平均分为2组，分别实施胸部常规剂量CT扫描（n=33, 120 kV, 300 mAs）和胸部低剂量CT扫描（n=33，100 kV，70 mAs），其中常规剂量组采用512×512矩阵，低剂量组采用1 024×1 024矩阵。同时对胸部低剂量组用4种不同权重的迭代算法进行处理（30%、50%、70%、90%），对比两种检查模式的辐射剂量和图像质量。结果：低剂量组的有效辐射剂量为（1.81±0.14） mSV，与常规剂量组（6.83±0.68） mSV相比降低73.5%（P<0.05）；采用1 024大矩阵、90%权重迭代算法的低剂量组图像的CNR、SNR均略低于采用512常规矩阵、90%权重迭代算法的常规剂量组，但差异无统计学意义（SNR：5.11±0.75 vs 5.38±0.41，CNR：5.37±0.33 vs 5.44±0.51, P>0.05）；低剂量组患者的肺窗、纵膈窗图像质量主观评分低于常规剂量组，但差异无统计学意义（肺窗：3.30±0.72 vs 3.39±0.78；纵膈窗：3.15±0.90 vs 3.36±0.82, P>0.05）。结论：使用MDCT进行胸部低剂量扫描，同时采用高分辨率重建技术及90%权重迭代算法可用于COVID-19肺炎筛查，可在保证图像质量的前提下显著降低患者所受辐射剂量。
Abstract:
Abstract: Objective To explore the application value of low-dose multidetector computed tomography (CT) scan combined with high-resolution reconstruction in the screening of COVID-19 pneumonia. Methods A total of 66 patients with suspected COVID-19 pneumonia who came to Lanzhou University Second Hospital from February 1, 2020 to March 1, 2020 were enrolled, and then randomly divided into 2 groups, namely conventional-dose CT scan group (n=33, 120 kV, 300 mAs) and low-dose CT scan group (n=33, 100 kV, 70 mAs). A 512×512 matrix was adopted in conventional-dose group, and a 1 024×1 024 matrix in low-dose group. Meanwhile, low-dose group was processed with 4 iterative algorithms with different weights (30%, 50%, 70%, 90%). The radiation dose and image quality of two groups were compared. Results The effective radiation dose of low-dose group was (1.81±0.14) mSV, which was reduced by 73.5% (P<0.05) compared with (6.83±0.68) mSV in conventional-dose group. The contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) of low-dose group with a 1 024×1 024 matrix and 90% weight iterative algorithm were slightly lower than those of conventional-dose group with a 512×512 matrix and 90% weight iterative algorithm, without statistical differences (SNR: 5.11±0.75 vs 5.38±0.41, CNR: 5.37±0.33 vs 5.44±0.51, P>0.05). The subjective image quality scores of pulmonary window and mediastinal window in low-dose group were lower than those in conventional-dose group, but the differences were not statistically significant (pulmonary window: 3.30±0.72 vs 3.39±0.78 mediastinal window: 3.15±0.90 vs 3.36±0.82, P>0.05). Conclusion Multidetector CT for low-dose scan combined with high-resolution reconstruction technique and 90% weight iterative algorithm can be applied for COVID-19 pneumonia screening, which can significantly reduce the radiation dose to patients while ensuring image quality.

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备注/Memo

备注/Memo:
【收稿日期】2020-11-16 【基金项目】兰州市人才创新创业项目（2016-RC-58） 【作者简介】王雁南，住院医师，研究方向：医学影像技术，E-mail: 956426938@qq.com 【通信作者】周晟，E-mail: lzzs@sina.com
更新日期/Last Update: 2021-04-29