[1]卢晨阳,张轴.CTA形态学-影像组学特征对颅内动脉瘤破裂及预后的预测模型[J].中国医学物理学杂志,2026,43(4):467-472.[doi:DOI:10.3969/j.issn.1005-202X.2026.04.007]
　LU Chenyang,ZHANG Zhou.Prediction model for intracranial aneurysm rupture and prognosis based on morphological and imaging features on CT angiography[J].Chinese Journal of Medical Physics,2026,43(4):467-472.[doi:DOI:10.3969/j.issn.1005-202X.2026.04.007]
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CTA形态学-影像组学特征对颅内动脉瘤破裂及预后的预测模型()

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
43卷
期数:
2026年第4期
页码:
467-472
栏目:
医学影像物理
出版日期:
2026-04-28

文章信息/Info

Title:
Prediction model for intracranial aneurysm rupture and prognosis based on morphological and imaging features on CT angiography
文章编号:
1005-202X（2026）04-0467-06
作者:
卢晨阳; 张轴
十堰市太和医院医学影像中心， 湖北 十堰 442000
Author(s):
LU Chenyang;  ZHANG Zhou
Medical Imaging Center, Taihe Hospital of Shiyan City, Shiyan 442000, China
关键词:
CT血管造影; 形态学; 影像组学; 颅内动脉瘤; 动脉瘤破裂
Keywords:
Keywords: CT angiography morphology imaging omics intracranial aneurysm aneurysm rupture
分类号:
R816.1
DOI:
DOI:10.3969/j.issn.1005-202X.2026.04.007
文献标志码:
A
摘要:
目的：研究CTA形态学-影像组学特征对颅内动脉瘤破裂及预后的预测模型。方法：采取回顾性研究，研究对象为2021年1月~2024年8月进行治疗的颅内动脉瘤患者100例，发生颅内动脉瘤破裂者31例，在随访28 d内死亡25例。分别对患者的一般资料以及影像学资料进行分析，采用Logistics分析造成颅内动脉瘤破裂以及死亡的危险因素。采用ROC曲线对以上模型的验证能力进行分析。结果：破裂组以及非破裂组、生存组以及死亡组患者的年龄、体质量指数、动脉瘤个数、动脉瘤最长直径、动脉瘤体颈比、动脉瘤宽度、动脉瘤瘤体宽度与瘤颈宽度比值、瘤体垂直高度、SurfaceArea、SurfaceVolumeRatio、Maxium2DDiameterSlice、Maximum2DDiameterColumn、Maximun2DDiameterRow、饮酒史、吸烟史、高血压史之间的差异存在统计学意义（P<0.05），是造成颅内动脉瘤破裂以及死亡的危险因素。结论：CTA形态学-影像组学特征对颅内动脉瘤破裂及预后的预测效果较好，可以作为临床早期判定不良预后的重要依据。
Abstract:
Abstract: Objective To explore the prediction model for intracranial aneurysm rupture and prognosis based on the morphological and imaging features derived from CT angiography. Methods A retrospective study was performed on 100 patients with intracranial aneurysms treated between January 2021 and August 2024. Of these, 31 had intracranial aneurysm ruptures, and 25 died within 28 days of follow-up. The general data and imaging data of patients were analyzed. Logistics regression was adopted to identify the risk factors for intracranial aneurysm rupture and mortality, and ROC curve was used to evaluate the predictive performance of the model. Results Statistically significant differences were observed between the ruptured and non-ruptured groups, as well as between the survivor and non-survivor groups, in the following factors: age, body mass index, number of aneurysms, longest diameter of aneurysms, body-neck ratio of aneurysms, aneurysm width, ratio of aneurysm body width to neck width, aneurysm vertical height, SurfaceArea, SurfaceVolumeRatio, Maxium2DDiameterSlice, Maximum2DDiameterColumn, Maximun2DDiameterRow, drinking history, smoking history, and hypertension history (all P<0.05). These factors were identified as risk factors for intracranial aneurysm rupture and mortality. Conclusion The morphological and imaging features on CT angiography demonstrate favorable predictive performance for intracranial aneurysm rupture and prognosis, and can serve as an important reference for the early prediction of poor prognosis.

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备注/Memo

备注/Memo:
【收稿日期】2025-11-21 【基金项目】湖北省自然科学基金青年项目（2022CFB853） 【作者简介】卢晨阳，技师，研究方向：头、腹部医学影像技术，E-mail: lu774631@163.com 【通信作者】张轴，主管技师，研究方向：头、腹部医学影像技术，E-mail: 12973683@qq.com
更新日期/Last Update: 2026-04-29