[1]刘颖,孙海涛,邓青萍,等.立体定向放射治疗计划不同剂量区间三维γ通过率分析[J].中国医学物理学杂志,2021,38(12):1508-1517.[doi:DOI:10.3969/j.issn.1005-202X.2021.12.010]
　LIU Ying,SUN Haitao,DENG Qingping,et al.Three-dimensional gamma passing rate in different dose ranges for stereotactic body radiotherapy[J].Chinese Journal of Medical Physics,2021,38(12):1508-1517.[doi:DOI:10.3969/j.issn.1005-202X.2021.12.010]
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立体定向放射治疗计划不同剂量区间三维γ通过率分析()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
38卷
期数:
2021年第12期
页码:
1508-1517
栏目:
医学放射物理
出版日期:
2021-12-24

文章信息/Info

Title:
Three-dimensional gamma passing rate in different dose ranges for stereotactic body radiotherapy
文章编号:
1005-202X（2021）12-1508-10
作者:
刘颖1; 孙海涛2; 邓青萍3; 袁玲1; 张红利1; 徐瑶瑶1; 张晓鹏1; 王鑫1; 石兴源1
1.广州医科大学附属第五医院放射治疗科， 广东 广州 510700； 2.中山市中医院医学影像放疗室， 广东 中山 528400； 3.惠州市中心人民医院设备科， 广东 惠州 516001
Author(s):
LIU Ying1;  SUN Haitao2;  DENG Qingping3;  YUAN Ling1;  ZHANG Hongli1;  XU Yaoyao1;  ZHANG Xiaopeng1;  WANG Xin1;  SHI Xingyuan1
1. Department of Radiotherapy, the Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou 510700, China 2. Department of Radiotherapy, Zhongshan Hospital of TCM, Zhongshan 528400, China 3. Department of Equipment, Huizhou Municipal Central Hospital, Huizhou 516001, China
关键词:
立体定向放射治疗; γ通过率; 剂量验证; 水模体
Keywords:
Keywords: stereotactic body radiotherapy gamma passing rate dose verification water phantom
分类号:
R815
DOI:
DOI:10.3969/j.issn.1005-202X.2021.12.010
文献标志码:
A
摘要:
【摘要】目的：为探究立体定向放射治疗（SBRT）剂量通过率的特点及敏感性，分析SBRT验证计划γ通过率。方法：选取38例SBRT计划移植到PTW的OCTAVIUS模体，在Verisoft软件中将PTW 1600SRS采集的二维剂量重建为三维剂量，用Matlab分析Verisoft重建出的三维剂量（Dp）与放射治疗计划系统计算的三维剂量（Dt）间的γ通过率，并分析不同阈值及不同剂量区间内的γ通过率，检验γ通过率对不同剂量区间的剂量增加的敏感度。结果：阈值为10%时，3 mm标准下的γ通过率均大于90%；不同标准下的γ通过率的趋势较一致；3%/3 mm标准下，11%~20%区间内的γ通过率最高，所有γ标准下，51%以上剂量区间内（即照射区内）γ通过率均值低于90%，且波动性极大；γ通过率对51%以下剂量区间内（即照射区外）剂量增加敏感度较高。结论：阈值越小，γ通过率越高；低剂量区的γ通过率高于高剂量区，γ通过率对低剂量区剂量增加较敏感。
Abstract:
Abstract: Objective To explore the characteristics and sensitiveness of gamma passing rate in stereotactic body radiotherapy (SBRT) by analyzing gamma passing rate for stereotactic radiotherapy (SBRT) verification plan. Methods A total of 38 SBRT plans were transplanted to the OCTAVIUS phantom of PTW, and the two-dimensional dose collected by PTW 1600SRS was reconstructed into three-dimensional dose using Verisoft. The gamma passing rates between three-dimensional dose reconstructed by Verisoft (Dp) and that calculated by treatment planning system (Dt) were analyzed by Matlab. In addition, the gamma passing rates under different thresholds and in different dose ranges were analyzed for testing the sensitiveness of gamma passing rate to dose increase in different dose ranges. Results The gamma passing rate at 3 mm criterion was higher than 90% when the threshold was 10%. The gamma passing rates at different criteria were in the same tread. At 3%/3 mm criterion, the highest gamma passing rate was found in the 11%-20% dose range. For all criteria, the mean gamma passing rate in dose range higher than 51% (inside radiation area) was lower than 90% and changed significantly. In dose range lower than 51% (outside radiation area), the gamma passing rate was highly sensitive to dose increase. Conclusion The smaller the threshold is, the higher the gamma passing rate is. The gamma passing rate of low-dose area is higher than that of high-dose area, and gamma passing rate is more sensitive to the dose increase in low-dose area.

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备注/Memo

备注/Memo:
【收稿日期】2021-09-02 【基金项目】广州市科技计划项目（201905010004） 【作者简介】刘颖，研究方向：放射物理学，E-mail: 1114605768@qq.com 【作者简介】邓青萍，中级职称，研究方向：放射治疗物理学，E-mal: 870077645@qq.com
更新日期/Last Update: 2021-12-24