[1]张冬艳,薛雁山,许芳,等.MRI-CT图像融合技术在颈椎肿瘤靶区勾画中的应用[J].中国医学物理学杂志,2022,39(5):551-555.[doi:DOI:10.3969/j.issn.1005-202X.2022.05.005]
　ZHANG Dongyan,XUE Yanshan,XU Fang,et al.Application of MRI-CT image fusion technology in delineation of cervical tumor target area[J].Chinese Journal of Medical Physics,2022,39(5):551-555.[doi:DOI:10.3969/j.issn.1005-202X.2022.05.005]
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MRI-CT图像融合技术在颈椎肿瘤靶区勾画中的应用()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
39卷
期数:
2022年第5期
页码:
551-555
栏目:
医学影像物理
出版日期:
2022-05-27

文章信息/Info

Title:
Application of MRI-CT image fusion technology in delineation of cervical tumor target area
文章编号:
1005-202X（2022）05-0551-05
作者:
张冬艳1; 薛雁山2; 许芳3; 宋晓婕1; 颜宝云1
1.山西中医药大学附属医院影像科， 山西 太原 030024； 2.山西医科大学第二医院影像科， 山西 太原 030000； 3.山西中医药大学附属医院肿瘤科， 山西 太原 030024
Author(s):
ZHANG Dongyan1;  XUE Yanshan2;  XU Fang3;  SONG Xiaojie1;  YAN Baoyun1
1. Department of Imaging, Affiliated Hospital of Shanxi University of Traditional Chinese Medicine, Taiyuan 030024, China 2. Department of Imaging, Second Hospital of Shanxi Medical University, Taiyuan 030000, China 3. Department of Oncology, Affiliated Hospital of Shanxi University of Traditional Chinese Medicine, Taiyuan 030024, China
关键词:
颈椎肿瘤; 磁共振成像; 计算机断层扫描术; 图像融合技术; 放射治疗; 靶区
Keywords:
Keywords: cervical tumor magnetic resonance imaging computed tomography image fusion technology radiotherapy target area
分类号:
R318；R738.1
DOI:
DOI:10.3969/j.issn.1005-202X.2022.05.005
文献标志码:
A
摘要:
目的：探讨基于MRI-CT图像融合技术对颈椎肿瘤靶区勾画和剂量参数的影响。方法：收集11例颈椎肿瘤放疗患者的影像学资料，将MRI与CT图像进行融合，比较MRI-CT与CT为基础图像的靶区体积差异以及剂量差异。对不同医师所勾画的靶区体积以及剂量差异进行比较分析。实施组内相关系数（ICC）可靠性分析。结果：（1）由1名肿瘤放疗医师所勾画靶区体积GTVMRI-CT显著大于GTVCT，脊髓MRI-CT体积显著小于脊髓CT（P<0.05）；5名肿瘤放疗医师所勾画靶区体积比较差异与1名肿瘤放疗医师趋势一致，不同影像为基础的靶区勾画体积重叠系数为0.83±0.15。（2）5名肿瘤放疗医师所勾画靶区，GTV以及脊髓变异系数（CV）MRI-CT均小于CVCT；ICC在GTV中分别为0.97与0.95，在脊髓为0.83与0.82。（3）GTV剂量MRI-CT Dmax显著低于CT Dmax，脊髓剂量MRI-CT [D2 cm3]同样显著低于CT [D2 cm3]（P<0.05）。结论：MRI-CT图像融合技术能更精确地勾画靶区体积以及准确计算放射剂量，不易造成靶区漏照，同时MRI-CT图像融合技术在不同医师间差异较小，可提高靶区勾画的一致性和可靠性，值得在临床推广使用。
Abstract:
Abstract: Objective To explore the effects of MRI-CT image fusion technology on the delineation of cervical tumor target area and dosimetric parameters. Methods The imaging data of 11 patients treated by radiotherapy for cervical tumor were collected. The fusion of MRI and CT images was carried out, and the volume difference and dosimetric difference of the target area delineated based on MRI-CT and CT were compared. The differences in the volume of the target area delineated by different physicians and the dosimetric differences were analyzed. Moreover, intraclass correlation coefficient (ICC) was used for reliability analysis. Results (1) The gross target volume in MRI-CT (GTVMRI-CT) which was delineated by a tumor radiotherapy physician was significantly larger than that of GTVCT, and the volume of spinal cord in MRI-CT (SpineMRI-CT) was significantly smaller than SpineCT (P<0.05). The volume differences of the target area delineated by 5 tumor radiotherapy physicians had the same trends with the results obtained by a tumor radiotherapy physician. The volume overlapping index of the target area delineated based on different images was 0.83±0.15. (2) For the target areas delineated by 5 tumor radiotherapy physicians, the CVMRI-CT of GTV and spine cord was less than CVCT. ICC was 0.97 and 0.95 for GTV, and 0.83 and 0.82 for spinal cord. (3) The MRI-CT Dmax of GTV was significantly lower than CT Dmax, and MRI-CT [D2 cm3] of spinal cord was also significantly lower than CT [D2 cm3] (P<0.05). Conclusion MRI-CT fusion technology is worthy of clinical promotion for it can achieve the accurate target area delineation and radiation dose calculation, not easy to cause missed exposure of the target area. Meanwhile, there are trivial differences among different doctors in using MRI-CT fusion technology, which improves the consistency and reliability of the target area delineation.

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备注/Memo

备注/Memo:
【收稿日期】2021-12-24 【基金项目】山西省卫生健康委科研项目（2019163） 【作者简介】张冬艳，硕士，主治医师，研究方向：神经系统及腹部影像诊断，E-mail: Aytem199@163.com 【通信作者】颜宝云，硕士，副主任医师，研究方向：肿瘤影像学，E-mail: zhesai3@yeah.net
更新日期/Last Update: 2022-05-27