[1]黎嘉敏,区杰浩,李晓丹,等.对比增强磁敏感加权成像序列与肺癌脑转移瘤检出的相关性[J].中国医学物理学杂志,2022,39(5):556-561.[doi:DOI:10.3969/j.issn.1005-202X.2022.05.006]
　LI Jiamin,OU Jiehao,et al.Correlation between contrast-enhanced SWI sequence and detection of brain metastases from lung cancer[J].Chinese Journal of Medical Physics,2022,39(5):556-561.[doi:DOI:10.3969/j.issn.1005-202X.2022.05.006]
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对比增强磁敏感加权成像序列与肺癌脑转移瘤检出的相关性()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
39卷
期数:
2022年第5期
页码:
556-561
栏目:
医学影像物理
出版日期:
2022-05-27

文章信息/Info

Title:
Correlation between contrast-enhanced SWI sequence and detection of brain metastases from lung cancer
文章编号:
1005-202X（2022）05-0556-06
作者:
黎嘉敏1; 2; 区杰浩2; 李晓丹2; 康庄3; 周美娟1
1.南方医科大学公共卫生学院放射医学系， 广东 广州 510515； 2.广东省人民医院（广东省医学科学院）放射科， 广东 广州 510080； 3.中山大学附属第三医院放射科， 广东 广州 510630
Author(s):
LI Jiamin1;  2;  OU Jiehao2;  LI Xiaodan2;  KANG Zhuang3;  ZHOU Meijuan1
1. Department of Radiation Medicine, School of Public Health, Southern Medical University, Guangzhou 510515, China 2. Department of Radiology, Guangdong Provincial Peoples Hospital (Guangdong Academy of Medical Sciences), Guangzhou 510080, China 3. Department of Radiology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China
关键词:
肺癌; 脑转移瘤; 磁敏感加权成像; 对比增强; 微出血
Keywords:
factors of microbleeds;  but the incidence of microbleeds caused by lung cancer brain metastasis is significantly higher. Keywords: lung cancer brain metastases susceptibility-weighted imaging contrast-enhanced microbleed
分类号:
R318；R734.2
DOI:
DOI:10.3969/j.issn.1005-202X.2022.05.006
文献标志码:
A
摘要:
目的：研究对比增强磁敏感加权成像（CE-SWI）与肺癌脑转移瘤检出的相关性。方法：病例组选取肺癌脑转移瘤病例50例，对照组选取高血压病例50例，分析SWI与CE-SWI检出微出血的病例数、病灶个数、最大直径，采用[χ2]检验分析两组检出的差异，采用Logistic回归分析CE-SWI与肺癌脑转移瘤、高血压微出血的相关性。结果：CE-SWI在病例组检出患者45例，病灶数127个，最大直径5.428（3.663, 11.405） mm；在对照组检出患者28例，病灶数121个，最大直径3.259（2.206, 4.325） mm，[χ2]检验得出两组病例检出均有统计学差异（P<0.05）。相关性检验中，病例组发生微出血的优势比高于高血压组，差异有统计学意义（P<0.05）。结论：CE-SWI对于微出血和脑转移瘤的检出敏感，肺癌脑转移、高血压都是微出血的危险因素，但肺癌脑转移瘤引起的微出血发生率显著增加。
Abstract:
Objective To study the correlation of contrast-enhanced susceptibility-weighted imaging (CE-SWI) to the detection of brain metastases from lung cancer. Methods Fifty cases of brain metastases from lung cancer were enrolled as case group, and 50 cases of hypertension as control group. The microbleeds, number of lesions and maximum diameter of lesions in patients were detected by SWI and CE-SWI, separately. Chi square test was used to analyze the difference in detection results between two groups and Logistic regression was used to analyze the correlations between CE-SWI and brain metastasis from lung cancer or hypertensive microbleeds. Results The CE-SWI findings showed that there were 45 patients with 127 lesions in case group, with the maximum lesion diameter of 5.428 (3.663, 11.405) mm, and that there were 28 patients with 121 lesions in control group, with the maximum lesion diameter of 3.259 (2.206, 4.325) mm. Chi square test showed that the detection results were statistically different in two groups (P<0.05). In the correlation test, the odds ratio of microbleeds in case group was higher than that in control group, with significant differences (P<0.05). Conclusion CE-SWI is sensitive to the detections of microbleeds and brain metastases. Both lung cancer brain metastasis and hypertension are risk factors of microbleeds, but the incidence of microbleeds caused by lung cancer brain metastasis is significantly higher.

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备注/Memo

备注/Memo:
【收稿日期】2022-01-15 【基金项目】广州市科技计划项目（202007030007） 【作者简介】黎嘉敏，技师，研究方向：磁共振成像技术，E-mail: 277672- 638@qq.com 【通信作者】周美娟，教授，研究方向：放射生物学，E-mail: lkzmj@smu.edu.cn
更新日期/Last Update: 2022-05-27