[1]袁世俊,李金凝,彭海腾,等.肝脏间叶性错构瘤的病理与CT表现[J].中国医学物理学杂志,2019,36(9):1029-1033.[doi:DOI:10.3969/j.issn.1005-202X.2019.09.007]
　YUAN Shijun,LI Jinning,PENG Haiteng,et al.Pathological and CT manifestations of mesenchymal hamartoma of the liver[J].Chinese Journal of Medical Physics,2019,36(9):1029-1033.[doi:DOI:10.3969/j.issn.1005-202X.2019.09.007]
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肝脏间叶性错构瘤的病理与CT表现()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
36卷
期数:
2019年第9期
页码:
1029-1033
栏目:
医学影像物理
出版日期:
2019-09-25

文章信息/Info

Title:
Pathological and CT manifestations of mesenchymal hamartoma of the liver
文章编号:
1005-202X（2019）09-1029-05
作者:
袁世俊; 李金凝; 彭海腾; 蔡静; 刘欢欢; 张财源; 汪登斌
上海交通大学医学院附属新华医院放射科， 上海 200092
Author(s):
YUAN Shijun;  LI Jinning;  PENG Haiteng;  CAI Jing;  LIU Huanhuan;  ZHANG Caiyuan;  WANG Dengbin
Department of Radiology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
关键词:
间叶性错构瘤; 肝脏; 儿童; CT
Keywords:
mesenchymal hamartoma;  liver;  children;  computed tomography
分类号:
R814.42；R735.7
DOI:
DOI:10.3969/j.issn.1005-202X.2019.09.007
文献标志码:
A
摘要:
 目的：研究宫颈癌术后放疗患者不同骨盆勾画及限量方式对调强放射治疗（IMRT）计划剂量的影响。方法：选取11例宫颈癌术后患者，对患者CT图像勾画靶区和小肠、直肠、膀胱、股骨头、髋骨、腰骶骨、骨盆等危及器官。针对每例患者分别设计3个计划，包括限制骨盆的IMRT（BM）计划、限制髋骨的IMRT（OC）计划以及限制髋骨和腰骶骨的IMRT（OC+LS）计划，并评估3组计划的靶区和危及器官的剂量分布。结果：3组计划的计划靶区覆盖率均能满足临床要求，且小肠、直肠、膀胱、股骨头等危及器官的剂量学参数相当，差异无统计学意义（P>0.05）。对于骨盆剂量，对髋骨和腰骶骨进行限量的IMRT（OC+LS）计划的骨盆Dmean、V10、V20、V30、V40和腰骶骨Dmean、V20、V30、V40均显著低于其他两个计划（P<0.05）。与IMRT（BM）计划相比，IMRT（OC+LS）计划可使骨盆V20和V30降低约10.1%和8.0%。与IMRT（OC）计划相比，IMRT（OC+LS）计划可使腰骶骨的V20和V30降低约17.6%和27.9%。IMRT（OC）计划髋骨的剂量略低于IMRT（OC+LS）计划，但二者剂量体积参数差异均在1%以内。结论：宫颈癌术后放疗行保护骨盆的IMRT计划时，若将髋骨和腰骶骨限量，则可以在在满足靶区临床要求以及常规危及器官保护的基础上，有效降低骨盆受量，更好地保护骨髓。
Abstract:
enrolled in the study. All the MHL in 5 children were located at the right lobe of the liver. The MHL in 4 children were double or multilocular cystic, with homogeneous cystic fluid, and the MHL in the other 1 case was cystic-solid, with non-uniform liquid density in the cyst, without enhancement or mild to moderate enhancement in the cystic wallin the cyst. Cystic walls showed no enhancement or mild to moderate enhancement. The 2 MHL lesions in the adult were located at the left and right lobes of the liver respectively, and both of which were solid. The lesions showed a slightly lower density on CT. After enhancement, the majority of the larger lesions had no enhancement, except local slightly and delayed enhancement, and the smaller lesions had slightly and delayed enhancement. Pathologically, the mesenchymal tissues with loose edema were separated into cysts by fibrotic tissues, and hyperplastic bile ducts and blood vessels were observed in pediatric MHL. Microscopically, adult MHL was characterized by hyperplastic and degenerative collagen fibers, with scattered liver cell islands, malformed blood vessels and bile ducts. Conclusion There were commonalities and differences in the clinical, pathological and CT findings of MHL in children and adults, which may be helpful for the clinical diagnosis of MHL.

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备注/Memo

备注/Memo:
【收稿日期】2019-06-19 【基金项目】国家重点研发计划（子课题）（2017YFC0109003） 【作者简介】袁世俊，主管技师，研究方向：胸腹部CT扫描技术与诊断，E-mail: yuanshijun@xinhuamed.com.cn 【通信作者】汪登斌，E-mail: wangdengbin@xinhuamed.com.cn
更新日期/Last Update: 2019-09-23