[1]梁鹏晨,李路易,常庆,等.微弧氧化技术在骨科钛植入体生物功能改性中的应用进展[J].中国医学物理学杂志,2019,36(11):1335-1341.[doi:DOI:10.3969/j.issn.1005-202X.2019.11.017]
 LIANG Pengchen,LI Luyi,CHANG Qing,et al.Progress on micro-arc oxidation technology in biological functional modification of orthopaedic titanium implants[J].Chinese Journal of Medical Physics,2019,36(11):1335-1341.[doi:DOI:10.3969/j.issn.1005-202X.2019.11.017]
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微弧氧化技术在骨科钛植入体生物功能改性中的应用进展()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
36卷
期数:
2019年第11期
页码:
1335-1341
栏目:
生物材料与力学
出版日期:
2019-11-25

文章信息/Info

Title:
Progress on micro-arc oxidation technology in biological functional modification of orthopaedic titanium implants
文章编号:
1005-202X(2019)11-1335-07
作者:
梁鹏晨1李路易1常庆2史俊峰3
1.上海中医药大学研究生院, 上海 200120; 2.上海健康医学院附属嘉定区中心医院临床科研中心, 上海 201800; 3.上海健康医学院分子影像学重点实验室, 上海 200120
Author(s):
LIANG Pengchen1 LI Luyi1 CHANG Qing2 SHI Junfeng3
1. Graduate School, Shanghai University of Traditional Chinese Medicine, Shanghai 200120, China; 2. Clinical Research Center, Jiading District Central Hospital Affiliated to Shanghai University of Medicine & Health Sciences, Shanghai 201800, China; 3. Shanghai Key Laboratory for Molecular Imaging, Shanghai University of Medicine & Health Sciences, Shanghai 200120, China
关键词:
微弧氧化钛植入体骨整合性抗菌性生物活性元素
Keywords:
micro-arc oxidation titanium implant osteointegration antibacterial activity biologically active element
分类号:
R318;TH781
DOI:
DOI:10.3969/j.issn.1005-202X.2019.11.017
文献标志码:
A
摘要:
微弧氧化是用于增强钛植入体的生物相容性和抗菌性的有效表面处理技术。在钛植入体表面制备生物活性元素组成的多孔涂层,是微弧氧化技术最具吸引力的特征。本研究主要介绍了微弧氧化的基本原理,阐述了该方法的技术优势,并总结了几种微弧氧化涂层的国内外研究进展;对含钙磷、银、铜、锌、硅的微弧氧化涂层,重点关注了对该类型涂层的骨整合性、抗菌性以及毒性的研究报道,旨在为研究者提供较为全面的视角,评估微弧氧化在骨科钛植入体上的应用进展,为后续临床研究提供参考。
Abstract:
Micro-arc oxidation is an effective surface treatment technology to enhance the biocompatibility and antibacterial activity of titanium implants. The preparation of porous coatings composed of bioactive elements on the surface of titanium implants is the most attractive feature of micro-arc oxidation technology. Herein the basic principle of micro-arc oxidation is mainly introduced; the technical advantages of the technology are expounded; and the research progress of several kinds of micro-arc oxidation coatings at home and abroad is summarized. The osteointegration, antibacterial activity and toxicity of micro-arc oxidation coatings containing calcium and phosphorus, silver, copper, zinc, and silicon are emphasized. The review provides a more comprehensive perspective for researchers to evaluate the progress of micro-arc oxidation technology in orthopaedic titanium implants, providing some reference for further clinical research.

相似文献/References:

[1]徐丰源,李德超,孙良庆,等. 电参数对钛微弧氧化膜层理化性能及细胞相容性的影响[J].中国医学物理学杂志,2018,35(11):1334.[doi:DOI:10.3969/j.issn.1005-202X.2018.11.018]
 XU Fengyuan,LI Dechao,SUN Liangqing,et al. Effects of electrical parameters on physical and chemical properties and cellular compatibility of micro-arc oxidation coat on titanium[J].Chinese Journal of Medical Physics,2018,35(11):1334.[doi:DOI:10.3969/j.issn.1005-202X.2018.11.018]

备注/Memo

备注/Memo:
【收稿日期】2019-07-15 【基金项目】国家自然科学基金(81670968) 【作者简介】梁鹏晨,硕士研究生,研究方向:钛植入体表面生物功能改性,E-mail: 398658408@qq.com 【通信作者】常庆,博士,副研究员,研究方向:中药提取物调控骨发育的分子机制,E-mail: jd_changq@sumhs.edu.cn;史俊峰,博士,讲师,研究方向:代谢及骨再生、药理基因组学,E-mail: strangephone@126.com(常庆与史俊峰为共同通信作者)
更新日期/Last Update: 2019-11-28