[1]杨耕,戴振晖,蔡春雅,等. 快速蒙特卡洛模拟调强放疗剂量计算的研究[J].中国医学物理学杂志,2018,35(4):384-388.[doi:DOI:10.3969/j.issn.1005-202X.2018.04.00]
　YANG Geng,DAI Zhenhui,CAI Chunya,et al. Fast Monte Caro simulation for dose calculation in intensity-modulated radiotherapy[J].Chinese Journal of Medical Physics,2018,35(4):384-388.[doi:DOI:10.3969/j.issn.1005-202X.2018.04.00]
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 快速蒙特卡洛模拟调强放疗剂量计算的研究()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
35卷
期数:
2018年第4期
页码:
384-388
栏目:
医学放射物理
出版日期:
2018-04-21

文章信息/Info

Title:
 Fast Monte Caro simulation for dose calculation in intensity-modulated radiotherapy
文章编号:
1005-202X（2018）04-0384-05
作者:
 杨耕; 戴振晖; 蔡春雅; 李飞; 张白霖; 朱远湖; 招什武; 王学涛
 广东省中医院放射治疗中心， 广东 广州 510006
Author(s):
 YANG Geng;  DAI Zhenhui;  CAI Chunya;  LI Fei;  ZHANG Bailin;  ZHU Yuanhu;  ZHAO Shiwu;  WANG Xuetao
 Department of Radiation Therapy, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510006, China
关键词:
 ; 蒙特卡洛模拟; 并行运算; 剂量验证; 调强放射治疗
Keywords:
 ; Monte Carlo simulation;  parallel computation;  dose verification;  intensity-modulated radiotherapy
分类号:
R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2018.04.00
文献标志码:
A
摘要:
 目的：提高蒙特卡洛模拟速度并应用于临床调强放疗剂量计算。 方法：运用BEAMnrc程序建立Varian_EDGE加速器6 MV FF与FFF模式束流模型，在DOSXYZnrc程序的基础上开发并行运算的Par-DOSXYZnrc（PDMC）剂量计算程序，与SYNCJAWS、SYNCHDMLC组件实现同步调强放疗剂量计算，并利用仿真模体和临床病例对该方法的精确性与运算效率进行评估。 结果：PDMC与DOSXYZnrc的剂量分布一致，与加速器测量值的偏差小于1%。PDMC在6核处理器中效率提升10.5倍以上，能够在0.74 h内完成调强放疗剂量计算，其效率随处理器核心数增加而增长。 结论：建立的PDMC能保证临床调强放疗病例剂量计算的准确性，同时提高的效率可满足临床调强放疗剂量计算的时间需求。
Abstract:
 Objective To improve the speed of Monte Carlo simulation and apply it into the dose calculation in intensity-modulated radiotherapy (IMRT). Methods Varian_EDGE linear accelerator 6 MV flattening filter and flattening filter free radiation source model were built with the use of BEAMnrc program. Then we developed a software-package PDMC with the foundation of DOSXYZnrc which is combined with SYNCJAWS and SYNCVMLC modules to achieve the synchronous IMRT dose calculation. Finally, the simulation phantoms and clinical cases were used to evaluate the accuracy and calculation efficiency of the proposed method. Results PDMC was in excellent agreement to DOSXYZnrc in terms of dose distributions, and the differences with linear accelerator measurements were less than 1%. The operating efficiency of PDMC implemented on 6-cores CUP had increased by 10.5 times, and the IMRT dose verification was completed in 0.74 h. With the increase of CPU-cores, the calculation efficiency was increasingly improved. Conclusion PDMC can guarantee the accuracy of the dose calculation in IMRT and improve calculation efficiency, satisfying the time requirements for IMRT dose calculation.

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备注/Memo

备注/Memo:
 【收稿日期】2018-01-18
【基金项目】广东省科技计划项目（2017ZC0153）
【作者简介】杨耕，助理工程师，研究方向：医学物理与放疗质控，E-mail: 601962294@qq.com
【通信作者】王学涛，主任物理师，E-mail: wangxuetao0625@126.com
更新日期/Last Update: 2018-04-23