[1]唐世强,邱小平,陈文韬,等. 宫颈癌术后不同射野数调强放射治疗与四野三维适形放射治疗的剂量学比较[J].中国医学物理学杂志,2018,35(2):183-186.[doi:DOI:10.3969/j.issn.1005-202X.2018.02.012]
　TANG Shiqiang,QIU Xiaoping,CHEN Wentao,et al. Different-field intensity-modulated radiotherapy vs four-field three-dimensional conformal radiotherapy following radical surgery for cervical carcinoma: a dosimetry comparison[J].Chinese Journal of Medical Physics,2018,35(2):183-186.[doi:DOI:10.3969/j.issn.1005-202X.2018.02.012]
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 宫颈癌术后不同射野数调强放射治疗与四野三维适形放射治疗的剂量学比较()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
35卷
期数:
2018年第2期
页码:
183-186
栏目:
医学放射物理
出版日期:
2018-02-08

文章信息/Info

Title:
 Different-field intensity-modulated radiotherapy vs four-field three-dimensional conformal radiotherapy following radical surgery for cervical carcinoma: a dosimetry comparison
文章编号:
1005-202X（2018）02-0183-04
作者:
 唐世强1; 2; 邱小平1; 陈文韬2; 贺夔2; 王志芳2; 何志鹏2
 1.南华大学核科学技术学院， 湖南 衡阳 421001； 2.郴州市第一人民医院放疗中心， 湖南 郴州 423000
Author(s):
 TANG Shiqiang1; 2;  QIU Xiaoping1;  CHEN Wentao2;  HE Kui2;  WANG Zhifang2;  HE Zhipeng2
 1. School of Nuclear Science and Technology, University of South China, Hengyang 421001, China; 2. Radiation Therapy Center, Chenzhou NO.1 People’s Hospital, Chenzhou 423000, China
关键词:
 ; 宫颈癌; 不同射野数; 调强放射治疗; 三维适形放射治疗; 剂量学
Keywords:
 ; cervical carcinoma;  different fields;  intensity-modulated radiotherapy;  three-dimensional conformal radiotherapy;  dosimetry
分类号:
R737.33
DOI:
DOI:10.3969/j.issn.1005-202X.2018.02.012
文献标志码:
A
摘要:
 目的：利用三维治疗计划系统对宫颈癌术后不同射野数调强放射治疗（IMRT）与三维适形放射治疗(3DCRT)的计划作剂量学比较，评价其剂量分布特点，试图根据不同情况选择最佳的治疗方案。 方法：选择20例宫颈癌术后患者，利用三维治疗计划系统对每个病例分别模拟三野、五野、七野IMRT计划与四野3DCRT计划。在剂量体积直方图上，比较靶区和正常组织器官照射剂量、靶区内剂量分布均匀性和适形指数。 结果：无论三野、五野、七野IMRT的靶区剂量覆盖和适形指数皆优于四野3DCRT，均匀性比较无显著差异。较四野3DCRT，IMRT能减少膀胱、直肠、小肠等正常器官的照射剂量。 结论：IMRT技术在保证肿瘤放射剂量的同时可减少并发症的发生，应该更广泛地应用于临床，同时对于经济条件受限的患者采用三野IMRT较四野3DCRT受益。
Abstract:
 Objective To compare the dosimetry of different-field intensity-modulated radiotherapy (IMRT) with four-field three-dimensional conformal radiotherapy (3DCRT) after radical surgery for cervical carcinoma for evaluating the dose distributions, and select the optimal treatment plan according to different situations. Methods Twenty patients receiving radical surgery for cervical carcinoma were selected, and different plans, namely three-, five- and seven-field IMRT plan and four-field 3DCRT, were designed for each patients. Based on the dose-volume histogram (DVH), the irradiation dose of target areas, normal tissues and organs, the conformal index and homogeneity index of dose distributions in target areas were compared. Results The conformal index and dose coverage of target areas in three-, five-and seven-field IMRT was superior to those in four-field 3DCRT, while the differences in homogeneity index were trivial. The irradiation doses of bladder, rectum, small intestine in IMRT were statistically lower as comparison with four-field 3DCRT. Conclusion IMRT should be more widely used in clinic for it can ensure the irradiation dose of tumor and reduce the incidence of complication. Moreover, compared with four-field 3DCRT, three-field IMRT is more beneficial for patients with poor economic conditions

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备注/Memo

备注/Memo:
 【收稿日期】2017-08-18
【作者简介】唐世强，在读硕士研究生，工程师，研究方向：肿瘤放疗物理，E-mail: tsq1982@sina.com.cn
【通信作者】邱小平，教授，硕士研究生导师，研究方向：辐射防护、医学辐射安全与防护，E-mail: nh6651@163.com
更新日期/Last Update: 2018-01-29