Effects of right median nerve stimulation combined with conventional treatment on SPECT/CT, cerebral hemodynamics and EEG synek grading in patients with severe traumatic brain injury(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2023年第11期
- Page:
- 1423-1427
- Research Field:
- 医学生物物理
- Publishing date:
Info
- Title:
- Effects of right median nerve stimulation combined with conventional treatment on SPECT/CT, cerebral hemodynamics and EEG synek grading in patients with severe traumatic brain injury
- Author(s):
- DU Yanping1; LIANG Jianguang1; WANG Yuhai2; ZHANG Xiahui1; JIN Dong1; JIANG Lixian1
- 1. Department of Neurosurgery, Traditional Chinese Medicine Hospital of Wuxi (Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine), Wuxi 214001, China 2. Department of Neurosurgery, No.904 Hospital of the Joint Logistics Support Force of the Peoples Liberation Army of China, Wuxi 214044, China
- Keywords:
- Keywords: severe traumatic brain injury right median nerve stimulation therapy single-photon emission computed tomography hemodynamics electroencephalogram
- PACS:
- R651.1；R816.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2023.11.017
- Abstract:
- Abstract: Objective To analyze the therapeutic effect of right median nerve stimulation therapy combined with conventional treatment in patients with severe traumatic brain injury (sTBI). Methods Sixty patients with sTBI were enrolled, all of whom were in coma, and the Glasgow coma score was lower than 9. The patients in control group (n=30) were treated with conventional treatment, while those in observation group (n=30) received right median nerve stimulation therapy in addition to conventional treatment, with the treatment cycle of 1 month. The two groups were compared in terms of therapeutic effect, cerebral hemodynamics, brainstem auditory evoked potential (BAEP) latency, and electroencephalogram (EEG) synek grade, and the cerebral blood perfusion was evaluated with SPECT/CT. Results After 1 month of treatment, the blood perfusion volume of motorsensory cortex and the thalamus in observation group was significantly higher than that in control group (P<0.05), and there was no significant difference in the blood perfusion volume of the hippocampus between two groups (P>0.05). The proportions of EEG synek grade I-Ⅲ, average blood flow velocity, regional cerebral blood flow (rCBF) and regional cerebral blood volume (rCBV) were higher in observation group than in control group (all P<0.05). The latency of BAEP Ⅰ, Ⅲ, Ⅴ, I-Ⅲ, Ⅲ-V in the left and right ear of observation group were shorter than those of control group (P<0.05). The 6-month follow-up showed that the proportion of conscious state and minimally conscious state was higher in observation group than in control group (P<0.05). Conclusion The combination of conventional treatment with right median nerve stimulation for sTBI can significantly increase the blood perfusion volume in the injured cortex and thalamus, promote the improvements of EEG synek grade, cerebral hemodynamics and nerve function, shorten BAEP latency, and improve the prognosis.
Last Update: 2023-11-24