Value of high-frequency ultrasound and CT in the differential diagnosis of benign and malignant superficial lymph node lesions(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第4期
- Page:
- 464-468
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Value of high-frequency ultrasound and CT in the differential diagnosis of benign and malignant superficial lymph node lesions
- Author(s):
- ZHOU Meijun; ZHU Sheng
- Department of Ultrasound, Affiliated Hospital of Xiangnan University, Chenzhou 423000, China
- Keywords:
- Keywords: superficial lymph node high-frequency ultrasound computed tomography differential diagnosis
- PACS:
- R445
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.04.013
- Abstract:
- Abstract: Objective To explore the value of ultrasound and computed tomography (CT) in the screening and diagnosis of superficial lymph node lesions. Methods A retrospective analysis was performed on the 96 patients with superficial lymph node lesions undergoing ultrasound and CT examinations. According to the results of pathological biopsy, the patients were divided into benign lymph node group (n=41) and malignant lymph node group (n=55). Based on the results of ultrasound and CT examination combined with pathological diagnosis, the sonographic characteristics of different types of superficial lymph nodes were described. Kappa consistency was applied to obtain the sensitivity, specificity, positive predictive value and negative predictive value of CT, ultrasound and combined detection. The longest and shortest diameters of lymph nodes were measured in high-frequency ultrasound image. Moreover, the blood flow resistance index (RI), arterial peak systolic velocity and end diastolic velocity were obtained by blood flow spectrum of color Doppler ultrasound and flow calculation formula. Results Compared with ultrasound and combined detection, CT had a lower diagnostic accuracy rate (P<0.05) and a higher misdiagnosis rate (P<0.05). The combined detection achieved the greatest AUC, which was 0.787, higher than 0.617 and 0.723 of CT and ultrasound (P<0.05). The long diameter, short diameter and RI measured by ultrasound in benign nodule group were significantly lower than those in malignant group (P<0.05), but arterial peak systolic velocity in benign nodule group was significantly higher (P<0.05). The AUC of long diameter, short diameter, RI, arterial peak systolic velocity, and combined detection for predicting superficial lymph node lesions were 0.753, 0.686, 0.787, 0.698 and 0.897, respectively, which indicated that the predicted value of combined detection was the highest (P<0.05). Conclusion The accuracy rates of CT combined with ultrasound and ultrasound alone are higher than that of CT in the diagnosis of benign and malignant superficial lymph node lesions, and the combination of CT and ultrasound has the same diagnostic value with color Doppler ultrasound. For the color Doppler ultrasound detection, the combined detection of long diameter, short diameter, vascular RI and arterial peak systolic velocity is of great predictive value for superficial lymph nodes.
Last Update: 2022-04-27