Abstract

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Title:: Preliminary study on the effects of electrodes array for tumor treating fields and scalp sparing technology on the dose distribution in radiotherapy

Author(s):: HU Xiaoyang1; HAN Lei1; WANG Yang1; 2; SUN Lei3; NI Chunxia1; LIU Ying4; 1. Department of Radiotherapy, Shanghai Gamma Hospital, Shanghai 200235, China 2. Center of Radiotherapy, Huashan Hospital of Fudan University, Shanghai 200040, China 3. Center of Cyberknife, Huashan Hospital of Fudan University, Shanghai 200040, China 4. School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China

Keywords:: Keywords: tumor treating field glioblastoma volumetric modulated arc therapy dose distribution scalp sparing technology

Abstract:: Abstract: Objective To study the effects of electrodes array for tumor treating fields (TTF) and scalp sparing technology on the radiation dose distribution. Methods The variations of dose distribution due to TTF electrodes array were measured in the study. Volumetric modulated arc therapy plans were designed on CT without TTF electrodes array and recalculated on CT with TTF electrodes array to investigate the effects of TTF electrodes array on dose distribution. The effect of different TTF electrodes array positions on the dose distribution was also analyzed. Moreover, scalp sparing plan was designed to compare the dose to the target areas and the scalp before and after scalp sparing. Results TTF electrodes array reduced the average dose to the target areas by about 0.55%, and increased the D20 cc, D30 cc, Dmean and Dmax to the scalp by 8.8%, 8.9%, 8.1% and 4.0%, respectively. The change of TTF electrode array position had little effect on the dose distribution. The comparison between scalp sparing or not showed that the D20 cc, D30 cc, Dmean and Dmax to the scalp in scalp sparing plan were decreased by 8.4%, 7.0%, 4.2% and 19.7%, respectively. Conclusion The effect of TTF electrodes array on the dose distribution in the target areas is acceptable, but it will make the scalp dose increase significantly. Scalp sparing plan can significantly reduce the scalp dose. It is worthy of a further study.