Evaluation of salivary gland functions in radiotherapy for head and neck tumors by 99mTcO4- dynamic imaging(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2019年第6期
- Page:
- 701-704
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Evaluation of salivary gland functions in radiotherapy for head and neck tumors by 99mTcO4- dynamic imaging
- Author(s):
- TANG Wuru1; WEI Song2; ZHANG Fa’en2; WEI Lingqun1; ZHAO Liang3; XIAO Guoyou4
- 1. Department of Nuclear Medicine, Hechi People’s Hospital, Hechi 547000, China; 2. Department of Oncology, Hechi People’s Hospital, Hechi 547000, China; 3. Department of Stomatology, Hechi People’s Hospital, Hechi 547000, China; 4. Department of Nuclear Medicine, Guangxi Medical University Affiliated Tumor Hospital, Nanning 530021, China
- Keywords:
- ; Keywords: head and neck tumors; radiotherapy; salivary gland dynamic imaging; salivary gland function
- PACS:
- R817.4
- DOI:
- DOI:10.3969/j.issn.1005-202X.2019.06.016
- Abstract:
- Abstract: Objective To observe the effects of 99mTcO4- dynamic imaging of salivary gland on the evaluation of salivary gland functions in radiotherapy for head and neck tumors. Methods Eighty patients with head and neck tumors who were admitted to Hechi People’s Hospital from March 2016 to September 2018 were enrolled in this study. The uptake and excretion of 99mTcO4- in 80 patients before and after radiotherapy for head and neck tumors were quantitatively analyzed with salivary gland dynamic imaging. According to age (<30 years old, 30-40 years old, 41-51 years old, and >51 years old), the enrolled patients were divided into 4 groups. The pathological types included squamous cell carcinoma, vesicular nuclear carcinoma and undifferentiated carcinoma. Whether gender, age and pathological type of patients with head and neck tumors had different effects on salivary gland functions after radiotherapy was investigated. Results After radiotherapy, the uptake rate and excretion rate of ipsilateral and contralateral salivary glands were significantly lower than those before radiotherapy, with statistical differences (P<0.05). There was no significant difference in the effects of gender, age and pathological type of patients with head and neck tumors on salivary gland functions after radiotherapy (P>0.05). Conclusion 99mTcO4- dynamic imaging of salivary gland can effectively evaluate the damages to salivary gland functions in patients with head and neck tumors due to static intensity-modulated radiotherapy.
Last Update: 2019-06-25