Comparison of two different systems for automatic segmentation of small-sized organs-at-risk in the head(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2022年第6期
- Page:
- 676-681
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Comparison of two different systems for automatic segmentation of small-sized organs-at-risk in the head
- Author(s):
- HOU Dongmei; ZHAO Yongrui; YIN Xujun; ZHANG Qiuhang; XU Jiankun
- Department of Radiotherapy, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
- Keywords:
- Keywords: automatic segmentation manual delineation organ-at-risk head tumor dose deviation
- PACS:
- R811.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2022.06.004
- Abstract:
- Abstract: Objective To compare the accuracies of MANTEIA and RT-Mind in the automatic segmentation of small-sized organs-at-risk (OAR) in the head. Methods In the computed tomography (CT) images and magnetic resonance (MR) images of 30 patients with head tumors, the OAR were auto-segmented by MANTEIA and RT-Mind (experience group 1) and further manually modified (experience group 2), and also manually delineated by a doctor (control group). The overlap index (OI), Dice similarity coefficient (DSC), Jaccard similarity coefficient (J) and dose deviation were calculated and compared between groups. Results For head OAR with relatively greater volumes (such as brainstem) or obvious differences in CT values (such as lens), the OI, DSC and J value were higher, and the dose deviations were lower. However, for small-sized OAR (such as optic chiasm, optic nerve, pituitary), the OI, DSC and J value were lower, and the dose deviations were higher. P-value analysis showed the differences in OI, DSC and J value between experience group A1 and control group were statistically significant (P<0.05). Except the OI of the lens and inner ear, there were significant differences between experience group B1 and control group in OI, DSC and J value (P<0.05). After manual modification based on auto-segmentation, the OI, DSC and J value were further improved, but there still existed discrepancy as compared with segmentation results in control group. Conclusion Automatic segmentation with the above-mentioned systems can meet the clinical needs of radiotherapy for head organs with relatively greater volumes or obvious differences in CT values. However, for small-sized OAR, manual delineation is still needed in clinical practice.
Last Update: 2022-06-27