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Biomechanical study of bone defects after curettage of benign subchondral lesions filled with MIIGX3 calcium sulfate bone cement(PDF)

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

Issue:
2021年第10期
Page:
1304-1307
Research Field:
生物材料与力学
Publishing date:

Info

Title:
Biomechanical study of bone defects after curettage of benign subchondral lesions filled with MIIGX3 calcium sulfate bone cement
Author(s):
LIU Xujian1 WANG Donglai1 LI Zenghuai1 FENG Qi1 CHANG Fujun2 FENG Jiangang1
1. the Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China 2. the 980th Hospital of PLA Joint Logistics Support Force, Shijiazhuang 050000, China
Keywords:
Keywords: MIIGX3 calcium sulfate bone cement benign subchondral lesions chondroma femur biomechanics
PACS:
R318.01;R738.3
DOI:
DOI:10.3969/j.issn.1005-202X.2021.10.022
Abstract:
Abstract: Objective To investigate the biomechanical characteristics of filling bone defects after curettage of benign subchondral lesions with MIIGX3 calcium sulfate cement. Methods Twenty patients with osteochondroma of the proximal femur were enrolled in the study. After curettage of the lesions, MIIGX3 calcium sulfate bone cement was used to fill the bone defects. The bone absorption and autologous bone replacement were observed by X-ray regularly. At 6 th months and 12 nd months after surgery, it was ensured that MIIGX3 calcium sulfate cement was absorbed completely and replaced by autogenous bone. The biological characteristics of the affected lower limbs of the two groups were measured using a central rotation dynamometer. Results The surgery was performed successfully in 20 patients. The patients recovered stably, and the incision was healed at the first stage. MIIGX3 was absorbed completely and replaced by autologous bone in 11-13 weeks, with an average of (12.23±1.22) weeks. The Barthel index at the 12nd month after surgery was higher than that at the 6th month after surgery (P<0.05) and moreover, compared with those at the 6th month after surgery, the torsional stiffness at 1.5°, the torque at 1.5°, and the compression stiffness at a load of 800 N were all higher at the 12nd month after surgery, but the compressive displacement at a load of 800 N was lower, and the differences were statistically significant (P<0.05). Conclusion Using MIIGX3 calcium sulfate bone cement to fill bone defects after curettage of benign subchondral lesions is suitable for promotion, because it has preferable biomechanical performance, and can achieve satisfactory postoperative recovery and activities of daily living.

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Last Update: 2021-10-29