Abstract

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Title:: Development of microfluidic concentration gradient chip and its application in biochemistry

Author(s):: SHI Huanhuan1; 2; CAO Yu1; ZHOU Yanuo1; 2; WAN Yaru1; 2; ZHAO Yali3; 1. Key Laboratory of Nondestructive Testing, Ministry of Education, Nanchang Hangkong University, Nanchang 330000, China 2. Department of Biomedical Engineering, School of Testing and Optoelectronic Engineering, Nanchang Hangkong University, Nanchang 330000, China 3. Changsha Hospital of Hunan Normal University/the Forth Hospital of Changsha, Changsha 410083

Keywords:: Keywords: microfluidic concentration gradient chip drug screening toxicity analysis chemotaxis materials synthesis review

Abstract:: Abstract: It is important to systematically study the interactions between samples and different concentrations of components in biochemical analysis. Microfluidic chip technology has been widely used in biochemical analysis in recent years, because it can realize accurate liquid control in micron-sized channel. Microfluidic concentration gradient chip is a tool that can rapidly construct stable biochemical concentration gradient and can be combined with most cell culture, chemical analysis and other techniques, offering a new platform for traditional biochemical analysis. Herein the formation mechanism of microfluidic concentration gradient chip and its application in biochemistry and other fields are reviewed, thereby providing a new idea for broadening the application research related to concentration gradient.