Abstract

Info

Title:: CT/MRI hybrid registration and its application in treatment planning system

Author(s):: WU Qian1; PI Yifei2; ZHOU Jieping3; 1. School of Humanistic Medicine, Anhui Medical University, Hefei 230032, China 2. Department of Physics, University of Science and Technology of China, Hefei 230026, China 3. Department of Radiation Oncology, Affiliated Hospital of University of Science and Technology of China, Hefei 230001, China

Keywords:: multi-modality image registration hybrid registration mutual information B-spline preprocessing

Abstract:: The methods for image registration in radiotherapy are investigated in the study. Aiming at CT and MRI commonly used in radiotherapy, a registration method based on hybrid framework is proposed. In the proposed method, image processing methods such as mask extraction of regions of interest and morphological operations as well as CPU multithreading parallel technology are used to greatly improve the registration speed, and a hybrid strategy of global and local registrations is adopted. Global rigid registration with an affine transformation is used to prevent the deviation between registered images, and then B-spline elastic registration is applied on regions of interest for adjusting local deformations. The experiments show that the preprocessing and acceleration strategy for rigid registration can increase the speed ratio by up to 10 times while maintaining its accuracy, and the test results reach the clinical requirements. In addition, the CT/MRI hybrid registration method based on GPU acceleration can achieve an average registration speed of 4 minutes.