Feasibility of automatic planning in intensity-modulated radiotherapy for postoperative cervical cancer patients(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2018年第4期
- Page:
- 394-398
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Feasibility of automatic planning in intensity-modulated radiotherapy for postoperative cervical cancer patients
- Author(s):
- WU Junxiang; KANG Shengwei; WANG Pei; TANG Bin; WU Fan; XU Jinghui; LI Jie
-
- Keywords:
- cervical cancer; automatic intensity-modulated radiotherapy plan; manual intensity-modulated radiotherapy plan; dosimetric parameters
- PACS:
- R815
- DOI:
- DOI:10.3969/j.issn.1005-202X.2018.04.005
- Abstract:
- Objective To investigate the feasibility of automatic intensity-modulated therapy (IMRT) planning for postoperative cervical cancer patients by comparing the dosimetric differences between automatic IMRT plan and manual IMRT plan. Methods The manual IMRT planning and automatic IMRT planning of Philips Pinnacle3 9.10 treatment planning system were used to design treatment plans for 25 cervical cancer patients. The dosimetric parameters of target areas and organs-at-risk, monitor unit, optimization times and planning time were compared between the two plans. Results No significant differences were found in the Dmean, D95, conformity index and homogeneity index of target areas between automatic and manual IMRT plans (P>0.05). Compared with manual IMRT plan, automatic IMRT plan showed better dosimetric parameters of organs-at-risk, having 2.5% reduction in bladder V40, 0.9% in rectum V40, 2.8% in bone V35, 4.2% in intestine V30, 5.2% in left femoral head V30 and 5.5% in right femoral head V30 (all P<0.05). Compared with manual IMRT plan, the automatic IMRT plan reduced the average optimization times from 3 times to 2 times and planning time from 69.5 min to 42.7 min. Moreover, the automatic IMRT plan had a higher monitor unit than manual IMRT plan (1 042 MU vs 931 MU). Conclusion Pinnacle3-based automatic IMRT planning is feasible in the IMRT planning for postoperative cervical cancer patients for automatic IMRT plan can significantly enhance efficiency and simultaneously improve plan quality.
Last Update: 2018-04-23