Abstract

Info

Title:: Fast Monte Caro simulation for dose calculation in intensity-modulated radiotherapy

Author(s):: YANG Geng; DAI Zhenhui; CAI Chunya; LI Fei; ZHANG Bailin; ZHU Yuanhu; ZHAO Shiwu; WANG Xuetao; Department of Radiation Therapy, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510006, China

Keywords:: ; Monte Carlo simulation; parallel computation; dose verification; intensity-modulated radiotherapy

Abstract:: Objective To improve the speed of Monte Carlo simulation and apply it into the dose calculation in intensity-modulated radiotherapy (IMRT). Methods Varian_EDGE linear accelerator 6 MV flattening filter and flattening filter free radiation source model were built with the use of BEAMnrc program. Then we developed a software-package PDMC with the foundation of DOSXYZnrc which is combined with SYNCJAWS and SYNCVMLC modules to achieve the synchronous IMRT dose calculation. Finally, the simulation phantoms and clinical cases were used to evaluate the accuracy and calculation efficiency of the proposed method. Results PDMC was in excellent agreement to DOSXYZnrc in terms of dose distributions, and the differences with linear accelerator measurements were less than 1%. The operating efficiency of PDMC implemented on 6-cores CUP had increased by 10.5 times, and the IMRT dose verification was completed in 0.74 h. With the increase of CPU-cores, the calculation efficiency was increasingly improved. Conclusion PDMC can guarantee the accuracy of the dose calculation in IMRT and improve calculation efficiency, satisfying the time requirements for IMRT dose calculation.