Abstract

Info

Title:: Simulation and experiment on cooling effect of cryolipolysis based on negative pressure suction

Author(s):: YANG Guoliang; XU Yi; Institute of Biothermal Science and Technology, University of Shanghai for Science and Technology, Shanghai 200093, China

Keywords:: Keywords: cryolipolysis simulation negative pressure suction blood perfusion fat reduction

Abstract:: Abstract: Objective To evaluate the cooling effect of cryolipolysis therapy and provide theoretical basis for clinical treatment. Methods A physical model was established based on the structure of negative pressure suction cryolipolysis equipment and evaluated the effects of different cryolipolysis temperatures and blood perfusion rate on the cooling effect by numerical simulation. The accuracy of the model was verified. Results The simulation results showed that the proportion of fat thickness below the cryolipolysis temperature is 10.11%-40.32% under different refrigerating temperature. Compared with the clinical fat reduction effect of 10.7%-37.5%, the simulation results are consistent with clinical results. A smaller fat blood perfusion rate can improve the cooling effect. However, when the fat blood perfusion rate is less than 1.44×10-4 s-1, the cooling effect of cryolipolysis is slightly improved. The test results also showed that the simulation and the test have the same cooling trend, and the temperature difference at the final moment is 1 ℃-2 ℃, which confirms the accuracy of the numerical simulation results. Conclusion The research results may provide a reliable theoretical basis for clinical evaluation and effect optimization of cryolipolysis.