[1]逯娅雯,孟文勃.基于计算机断层扫描和磁共振胰胆管造影的扩张胆道及其毗邻结构的数字化精确建模研究[J].中国医学物理学杂志,2023,40(7):833-840.[doi:DOI:10.3969/j.issn.1005-202X.2023.07.007]
　LU Yawen,MENG Wenbo,Digital modeling of dilated biliary tract and its adjacent structures using computed tomography and magnetic resonance cholangiopancreatography[J].Chinese Journal of Medical Physics,2023,40(7):833-840.[doi:DOI:10.3969/j.issn.1005-202X.2023.07.007]
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基于计算机断层扫描和磁共振胰胆管造影的扩张胆道及其毗邻结构的数字化精确建模研究()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
40卷
期数:
2023年第7期
页码:
833-840
栏目:
医学影像物理
出版日期:
2023-07-15

文章信息/Info

Title:
Digital modeling of dilated biliary tract and its adjacent structures using computed tomography and magnetic resonance cholangiopancreatography
文章编号:
1005-202X（2023）07-0833-08
作者:
逯娅雯1; 孟文勃1; 2
1.兰州大学第一临床医学院， 甘肃 兰州 730000； 2.兰州大学第一医院普外科/甘肃省生物治疗与再生医学重点实验室/甘肃省肝胆胰外科研究所， 甘肃 兰州 730000
Author(s):
LU Yawen1;  MENG Wenbo1;  2
1. First Clinical Medical College, Lanzhou University, Lanzhou 730000, China 2. Gansu Institute of Hepatobiliary and Pancreatic Surgery/Key Laboratory of Biological Therapy and Regenerative Medicine Transformation of Gansu Province/Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, China
关键词:
胆道疾病; 三维重建; Mimics软件; 磁共振胰胆管造影; 计算机断层扫描
Keywords:
Keywords: biliary tract disease three-dimensional reconstruction Mimics software magnetic resonance cholangiopancreatography computed tomography
分类号:
R318；R657.4
DOI:
DOI:10.3969/j.issn.1005-202X.2023.07.007
文献标志码:
A
摘要:
目的：利用Mimics医学影像控制软件完整重建扩张胆道及其毗邻结构的三维模型，为磁感应热疗等医工学科交叉研究提供真实模型基础。方法：采集胆道下段梗阻患者的计算机断层扫描（CT）和磁共振胰胆管造影（MRCP）扫描数据，在Mimics软件中进行图像分割、断面充填、蒙版编辑，构建胆道及其毗邻结构的精确数字化模型并将其输入COMSOL软件进行有限元离散，验证模型的仿真运算潜能。结果：完整构建了扩张胆道，肝脏，肝脏静脉系统，胆囊，胰管及胆胰管交汇处的部分十二指肠，整个模型的分辨率为1 mm，并且为STL格式，可以方便地应用于多种CAD软件中（比如COMSOL、AUTO-CAD等）。结论：利用Mimics软件可以精确建立高精度的扩张胆道及其毗邻结构三维重建模型，为后续该模型在胆道疾病如胆道肿瘤的磁感应热疗多学科临床应用创建了良好的铺垫。
Abstract:
Abstract: Objective To reconstruct a three-dimensional model of biliary tract and its adjacent structure using Mimics software for providing a real model basis for medical and engineering integration application such as magnetic induction hyperthermia. Methods The computed tomography (CT) and magnetic resonance cholangiopancreatography (MRCP) scan data were collected from patients with lower biliary obstruction. Image segmentation, section filling and mask editing were carried out in Mimics software. The digital model of biliary tract and its adjacent structure was constructed and then input into COMSOL software for finite element discretization to verify the potential of the model for simulation operation. Results The dilated biliary tract, liver, hepatic venous system, gallbladder, pancreatic duct, and part of duodenum at the junction of biliopancreatic duct were completely constructed. The resolution of the whole model was 1 mm, and it was in stereolithography (STL) format of digital model file, which enabled the model be applied to various computer-aided design software such as COMSOL and AUTO-CAD. Conclusion A high-precision three-dimensional reconstruction model of the biliary tract and its adjacent structures can be accurately established using Mimics software, which creates a foundation for the subsequent multidisciplinary application of the model in biliary tract diseases, such as magnetic induction hyperthermia for biliary tract tumors.

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备注/Memo

备注/Memo:
【收稿日期】2023-02-16 【基金项目】国家自然科学基金（32160255）；甘肃省科技重大专项计划（1602FKDA001）；甘肃省自然科学基金（20JR10RA676）；甘肃省级国际合作资助项目（20YF8WA085）；兰州市城关区科技计划（2019RCCX0038, 2020JSCX0043） 【作者简介】逯娅雯，在读博士，E-mail: luyw20@lzu.edu.cn 【通信作者】孟文勃，博士，博士生导师，教授，研究方向：肝胆胰外科疾病、消化道肿瘤、内镜微创外科疾病、器官移植，E-mail: mengwb@lzu.edu.cn
更新日期/Last Update: 2023-07-15