[1]赵洪明,彭红梅,张东威,等.椎动脉狭窄临床病例介入治疗前后椎基底动脉血流状况分析[J].中国医学物理学杂志,2022,39(9):1182-1188.[doi:DOI:10.3969/j.issn.1005-202X.2022.09.020]
 ZHAO Hongming,PENG Hongmei,ZHANG Dongwei,et al.Status of blood flow in vertebrobasilar artery before and after interventional treatment: an analysis of a case of vertebral artery stenosis[J].Chinese Journal of Medical Physics,2022,39(9):1182-1188.[doi:DOI:10.3969/j.issn.1005-202X.2022.09.020]
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椎动脉狭窄临床病例介入治疗前后椎基底动脉血流状况分析()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
39卷
期数:
2022年第9期
页码:
1182-1188
栏目:
生物材料与力学
出版日期:
2022-11-02

文章信息/Info

Title:
Status of blood flow in vertebrobasilar artery before and after interventional treatment: an analysis of a case of vertebral artery stenosis
文章编号:
1005-202X(2022)09-1182-07
作者:
赵洪明1彭红梅1张东威2张红娜3
1.内蒙古民族大学数理学院, 内蒙古 通辽 028000; 2.内蒙古民族大学附属医院神经内科, 内蒙古 通辽 028007; 3.内蒙古民族大学工学院, 内蒙古 通辽 028000
Author(s):
ZHAO Hongming1 PENG Hongmei1 ZHANG Dongwei2 ZHANG Hongna3
1. College of Mathematics and Physics, Inner Mongolia Minzu University, Tongliao 028000, China 2. Department of Neurology, Affiliated Hospital of Inner Mongolia Minzu University, Tongliao 028007, China 3. College of Engineering, Inner Mongolia Minzu University, Tongliao 028000, China
关键词:
流固耦合椎动脉颅内段狭窄支架植入血流动力学
Keywords:
Keywords: fluid-solid coupling intracranial vertebral artery stenosis stent implantation hemodynamics
分类号:
R318.01;O357.1
DOI:
DOI:10.3969/j.issn.1005-202X.2022.09.020
文献标志码:
A
摘要:
目的:基于血液和弹性血管壁相互作用的流固耦合方法,探究1例椎动脉颅内段狭窄的临床病例支架植入前后椎基底动脉的血流动力学特性。方法:应用医学建模软件对二维CT数据进行三维重建,得到支架植入前后的椎基底动脉血管模型,采用流固耦合方法对支架植入前后的椎基底动脉血流特性进行数值模拟,分析椎基底动脉的血流动力学特性。结果:支架植入前后椎基底动脉的血液流场、血液压力、血管壁面切应力以及管壁形变量有显著的变化。在支架植入后,基底动脉中间部位两侧受力变得均匀,椎基底动脉内血流速度明显增大,支架植入处压力增大,支架上游压力和支架处切应力减小。结论:在介入治疗后,椎基底动脉内的血流环境及受力情况得到明显改善,当椎动脉发生狭窄后应及时干预治疗,避免累及基底动脉和后循环系统。
Abstract:
Abstract: Objective To explore the hemodynamic characteristics in the vertebrobasilar artery before and after stent implantation in a case of intracranial vertebral artery stenosis using the fluid-solid coupling method based on the interaction of blood and elastic vessel wall. Methods Medical modeling software was used for the 3D reconstruction of 2D CT data to obtain the vertebrobasilar artery model before and after stent implantation. Then the blood flow characteristics in the vertebrobasilar artery before and after stent implantation were numerically simulated using fluid-solid coupling method for analyzing the hemodynamic characteristics in the vertebrobasilar artery. Results The blood flow field, blood pressure, vessel wall shear stress and vessel wall shape of vertebrobasilar artery after stent implantation were significantly different from those before stent implantation. After stent implantation, the force on both sides of the middle part of the basilar artery became uniform, the blood flow velocity increased significantly, the pressure at the stent implantation increased, and the upstream pressure and shear stress at the stent decreased. Conclusion After interventional treatment, the blood flow environment and stress in the vertebrobasilar artery are significantly improved. Timely intervention should be performed after the occurrence of vertebral artery stenosis to avoid involving the basilar artery and the posterior circulation system.

相似文献/References:

[1]杨金有,刘 静,杨华哲,等.血栓后髂主动脉的流固耦合模拟方法研究[J].中国医学物理学杂志,2014,31(03):4941.[doi:10.3969/j.issn.1005-202X.2014.03.022]
[2]岳树坤,刘忠良,刘振泽,等. 血液流动状态下锥形血管的弹性变形分析[J].中国医学物理学杂志,2017,34(4):410.[doi:DOI:10.3969/j.issn.1005-202X.2017.04.018]

备注/Memo

备注/Memo:
【收稿日期】2022-05-18 【基金项目】国家自然科学基金(11362015, 82060816);内蒙古自治区自然科学基金(NJZY21435, 2018LH01005) 【作者简介】赵洪明,研究方向:计算生物流体力学,E-mail: 1126010996@qq.com 【通信作者】彭红梅,教授,研究方向:计算生物流体力学,E-mail: phm16888@126.com
更新日期/Last Update: 2022-09-27