[1]宋婷,张晓,高妮,等.强脉冲光联合Nd:YAG激光治疗黄褐斑疗效观察[J].中国医学物理学杂志,2021,38(12):1535-1537.[doi:DOI:10.3969/j.issn.1005-202X.2021.12.014]
 SONG Ting,ZHANG Xiao,GAO Ni,et al.Therapeutic efficacy of intense pulsed light combined with Nd:YAG laser for treatment of chloasma[J].Chinese Journal of Medical Physics,2021,38(12):1535-1537.[doi:DOI:10.3969/j.issn.1005-202X.2021.12.014]
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强脉冲光联合Nd:YAG激光治疗黄褐斑疗效观察()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
38卷
期数:
2021年第12期
页码:
1535-1537
栏目:
医学信号处理与医学仪器
出版日期:
2021-12-24

文章信息/Info

Title:
Therapeutic efficacy of intense pulsed light combined with Nd:YAG laser for treatment of chloasma
文章编号:
1005-202X(2021)12-1535-03
作者:
宋婷张晓高妮宋璞
第四军医大学西京皮肤医院, 陕西 西安 710032
Author(s):
SONG Ting ZHANG Xiao GAO Ni SONG Pu
Department of Dermatology, the Fourth Military Medical University, Xian 710032, China
关键词:
黄褐斑强脉冲光Nd:YAG激光联合治疗
Keywords:
Keywords: melasma intense pulsed light Nd:YAG laser combined treatment
分类号:
R318.51;R616.4
DOI:
DOI:10.3969/j.issn.1005-202X.2021.12.014
文献标志码:
A
摘要:
目的:探讨强脉冲光联合Nd:YAG激光治疗黄褐斑的疗效。方法:60例患者按治疗方法不同分成3组:强脉冲光组、Nd:YAG激光组、联合组(强脉冲光联合Nd:YAG激光组),每组20例患者,观察3组患者疗效和副作用。结果:3组之间疗效两两比较采用Mann-Whitney秩和检验,强脉冲光组和激光组疗效无显著差异,而联合组疗效显著好于强脉冲光组(Z=7.123, P=0.024)和激光组(Z=6.024, P=0.030)。3组患者治疗后均无出现色素沉着加重、色素脱失病等不良反应。强脉冲光组和激光组的满意度无显著差异,而联合组的满意度显著好于强脉冲光组(Z=7.361, P=0.029)和激光组(Z=6.831, P=0.027)。结论:强脉冲光联合Nd:YAG激光治疗黄褐斑是一种安全有效的治疗方法,值得临床推广。
Abstract:
Abstract: Objective To investigate the clinical efficacy of intense pulsed light combined with Nd:YAG laser in the treatment of melasma. Methods According to different treatment methods, 60 patients were divided into 3 groups, namely intense pulsed light group, Nd:YAG laser group and combined treatment group (intense pulsed light combined with Nd:YAG laser group), with 20 patients in each group. The therapeutic efficacies and side effects of 3 groups were observed. Results The results of Mann-Whitney rank sum test for pairwise comparison on therapeutic efficacy showed that there was no significant difference between intense pulsed light group and laser group, and that the therapeutic efficacy of combined treatment group was significantly higher than that of intense pulsed light group (Z=7.123, P=0.024) and laser group (Z=6.024, P=0.030). All 60 patients had no adverse reactions such as aggravation of pigmentation and depigmentation disease. No significant difference was found in the degree of satisfaction between intense pulsed light group and laser group, but the degree of satisfaction of combined treatment group was significantly higher than that of the intense pulsed light group (Z=7.361, P=0.029) and laser group (Z=6.831, P=0.027). Conclusion Intense pulse light combined with Nd:YAG laser which is a safe and effective treatment method for melasma is worthy of clinical promotion.

相似文献/References:

[1]张予晋,许 斌.Q开关Nd:YAG激光联合左旋维生素C离子导入治疗黄褐斑的临床观察[J].中国医学物理学杂志,2014,31(02):4839.[doi:10.3969/j.issn.1005-202X.2014.02.027]

备注/Memo

备注/Memo:
【收稿日期】2021-06-15 【基金项目】国家自然科学基金(82173436) 【作者简介】宋婷,研究方向:皮肤激光美容,E-mail: song0357@163.com 【通信作者】宋璞,博士,研究方向:皮肤美容、特应性皮炎,E-mail: songpu@fmmu.edu.cn
更新日期/Last Update: 2021-12-24