[1]杜钟名,方继良,陆梦馨,等.针刺中风患者阳陵泉后度中心性及动态度中心性变异系数变化的fMRI研究[J].中国医学物理学杂志,2022,39(1):38-43.[doi:DOI:10.3969/j.issn.1005-202X.2022.01.007]
 DU Zhongming,FANG Jiliang,et al.Degree centrality and coefficient of variation of dynamic degree centrality after acupuncturing Yanglingquan in stroke patients: a fMRI study[J].Chinese Journal of Medical Physics,2022,39(1):38-43.[doi:DOI:10.3969/j.issn.1005-202X.2022.01.007]
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针刺中风患者阳陵泉后度中心性及动态度中心性变异系数变化的fMRI研究()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
39卷
期数:
2022年第1期
页码:
38-43
栏目:
医学影像物理
出版日期:
2022-01-17

文章信息/Info

Title:
Degree centrality and coefficient of variation of dynamic degree centrality after acupuncturing Yanglingquan in stroke patients: a fMRI study
文章编号:
1005-202X(2022)01-0038-06
作者:
杜钟名12方继良2陆梦馨3江澜3赵吉平1邹忆怀3
1.北京中医药大学东直门医院针灸科, 北京 100700; 2.中国中医科学院广安门医院放射科, 北京 100053; 3.北京中医药大学东直门医院脑病科, 北京 100700
Author(s):
DU Zhongming1 2 FANG Jiliang2 LU Mengxin3 JIANG Lan3 ZHAO Jiping1 ZOU Yihuai3
1.Department of Acupuncture and Moxibustion, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China 2. Department of Radiology, Guanganmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China 3. Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
关键词:
脑梗死针灸功能磁共振度中心性动态度中心性
Keywords:
Keywords: cerebral infarction acupuncture functional magnetic resonance degree centrality dynamic degree centrality
分类号:
R318
DOI:
DOI:10.3969/j.issn.1005-202X.2022.01.007
文献标志码:
A
摘要:
目的:借助功能磁共振成像技术探索中风偏瘫患者度中心性(DC)及动态度中心性(DDC)变异系数针刺前后的差异。方法:选取发病1个月内右侧梗死的中风患者,共18例,进行基本资料的获取及Fugl-Meyer运动功能评分法(FMA)、Brunnstrom评价法的评估,采集静息态、针刺态的功能磁共振图像,进行全脑DC、DDC变异系数的比较。采用偏相关分析方法对DC、DDC变异系数和临床数据、评分进行分析。结果:针刺态与静息态的DC在左侧顶下小叶存在统计学差异(P<0.05),针刺态与静息态的DDC变异系数在右侧额上回、右侧额中回存在统计学差异(P<0.05)。纠偏后,年龄和左侧顶下小叶针刺态DDC变异系数具有相关性,病程和左侧顶下小叶静息态DDC变异系数具有相关性,下肢Brunnstrom评分和右侧额上回、右侧额中回针刺态DC具有相关性。结论:DC及DDC变异系数在针刺态中存在不同于静息态的变化,且DDC变异系数与病程、年龄和运动功能均具有相关性,表明针刺对中风患者脑功能,尤其是运动相关脑功能的调整功能,并反映出针刺态脑功能的持续变化,为针刺留针提供证据支持。
Abstract:
Abstract: Objective To use functional magnetic imaging (fMRI) technology for exploring the differences in degree centrality (DC) and coefficient of variation of dynamic degree centrality (DDC) in stroke patients before and after acupuncture. Methods A total of 18 stroke patients with left hemiplegia within a month after onset were enrolled in the study. After general information acquisition and Brunnstrom and Fugl-Meyer assessments, the fMRI images of resting-state and acupuncture-state were collected, and the DC and coefficient of variation of DDC of the whole brain were compared. Partial correlation analysis method was used to analyze the corrections of DC and coefficient of variation of DDC with clinical data and assessment scores. Results Statistical differences were found in DC at the left inferior parietal lobule between acupuncture-state and resting-state (P<0.05) , and in the coefficient of variation of DDC at the right superior frontal gyrus and the right middle frontal gyrus between acupuncture-state and restin-state (P<0.05). After correction, there were correlations between age and the acupuncture-state coefficient of variation of DDC at the left inferior parietal lobule, between the course of disease and the resting-state coefficient of variation of DDC at the left inferior parietal leaflet lobule, between Brunnstrom score of lower limbs and the acupuncture-state DC at the right superior frontal gyrus and the right middle frontal gyrus. Conclusion The DC and the coefficient of variation of DDC of acupuncture-state are different from those of resting-state, and the coefficient of variation of DDC is related to the course of disease, age and motor function, indicating the regulatory effects of acupuncture on brains functions of stroke patients, especially the exercise-related functions, and reflecting the continuous changes of brain functions during needle retention, which provides evidence support for needle retention.

相似文献/References:

[1]母晓明,吕晓玲,王晓琴,等. 运动疗法在脑梗死患者中后期康复中的应用效果 [J].中国医学物理学杂志,2018,35(6):724.[doi:DOI:10.3969/j.issn.1005-202X.2018.06.019]
 MU Xiaoming,LÜ,Xiaoling,et al. Application of exercise therapy in rehabilitation of patients with cerebral infarction in the middle and later periods[J].Chinese Journal of Medical Physics,2018,35(1):724.[doi:DOI:10.3969/j.issn.1005-202X.2018.06.019]
[2]陈玉,周泽仁,庞崇祥,等. 超声波治疗脑梗死恢复期的疗效观察[J].中国医学物理学杂志,2018,35(7):855.[doi:DOI:10.3969/j.issn.1005-202X.2018.07.022]
 CHEN Yu,ZHOU Zeren,PANG Chongxiang,et al. Curative effect of ultrasound waves in the treatment of cerebral infarction at convalescence[J].Chinese Journal of Medical Physics,2018,35(1):855.[doi:DOI:10.3969/j.issn.1005-202X.2018.07.022]

备注/Memo

备注/Memo:
【收稿日期】2021-08-22 【基金项目】国家自然科学基金(81873257);北京市自然科学基金(7182104) 【作者简介】杜钟名,博士,研究方向:中医脑病学、针灸推拿学,E-mail: 13121037307@163.com 【通信作者】邹忆怀,博士生导师,主任医师,研究方向:中医脑病学,E-mail: zouyihuai2004@163.com;赵吉平,博士生导师,主任医师,研究方向:针灸推拿学,E-mail: zjp7883@sina.com
更新日期/Last Update: 2022-01-17