[1]阳露,余辉,张国前,等.基于ArcCHECK-3DVH系统的鼻咽癌容积旋转调强放疗三维剂量验证研究[J].中国医学物理学杂志,2020,37(12):1506-1512.[doi:DOI:10.3969/j.issn.1005-202X.2020.12.007]
　YANG Lu,YU Hui,ZHANG Guoqian,et al.The study of three-dimensional dosimetric verification of volumetric-modulated arc therapy for nasopharyngeal carcinoma based on ArcCHECK-3DVH system[J].Chinese Journal of Medical Physics,2020,37(12):1506-1512.[doi:DOI:10.3969/j.issn.1005-202X.2020.12.007]
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基于ArcCHECK-3DVH系统的鼻咽癌容积旋转调强放疗三维剂量验证研究()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
37
期数:
2020年第12期
页码:
1506-1512
栏目:
医学放射物理
出版日期:
2020-12-30

文章信息/Info

Title:
The study of three-dimensional dosimetric verification of volumetric-modulated arc therapy for nasopharyngeal carcinoma based on ArcCHECK-3DVH system
文章编号:
1005-202X（2020）12-1506-07
作者:
阳露; 余辉; 张国前; 张全彬; 张书旭
广州医科大学附属肿瘤医院放疗中心， 广东 广州 510095
Author(s):
YANG Lu;  YU Hui;  ZHANG Guoqian;  ZHANG Quanbin;  ZHANG Shuxu
Radiotherapy Center, Cancer Center of Guangzhou Medical University, Guangzhou 510095, China
关键词:
ArcCHECK; 3DVH; 鼻咽癌; 容积旋转调强放疗; 三维剂量验证
Keywords:
ArcCHECK 3DVH nasopharyngeal carcinoma volumetric-modulated arc therapy three-dimensional dosimetric verification
分类号:
R815.6；R739.6
DOI:
DOI:10.3969/j.issn.1005-202X.2020.12.007
文献标志码:
A
摘要:
目的：探讨ArcCHECK-3DVH系统在鼻咽癌容积旋转调强放疗（VMAT）三维剂量验证中的应用。方法：选取基于Monaco治疗计划系统（TPS）制定的20例鼻咽癌患者VMAT计划，利用ArcCHECK-3DVH系统进行患者计划的验证。比较TPS计算剂量与ArcCHECK-3DVH系统基于测量重建剂量的三维γ通过率（3%/3 mm, TH=10%），以及靶区剂量参数[D98%]、[D2%]和[Dmean]与危及器官剂量参数[Dmax]和[Dmean]等。结果：患者计划验证的三维γ通过率为98.20%（97.75%, 99.20%），TPS计算靶区内剂量和ArcCHECK-3DVH重建的剂量在[D98%]、[D2%]和[Dmean]参数上的差异值大部分小于3%，极个别情况的最大差异值在5%以内，绝大部分患者除PGTVnd外的各个靶区γ通过率为90%以上；各个危及器官对应的[Dmax]和[Dmean]剂量参数差异值均小于6%，γ通过率均在93%以上。结论：ArcCHECK-3DVH系统重建的剂量结果与TPS计算结果符合较好，为鼻咽癌VMAT计划剂量验证提供了丰富的剂量参数信息，有助于患者治疗计划的质量验证。
Abstract:
Objective To investigate the application of ArcCHECK-3DVH system in three-dimensional dosimetric verification of volumetric-modulated arc therapy (VMAT) for nasopharyngeal carcinoma (NPC). Methods 20 WMAT treatment plans based on Monaco Treatment Planning System (TPS) for NPC have been selected to perform the dosimetric verification by using the ArcCHECK-3DVH system. The 3D γ-pass rates of the TPS dose calculation and ArcCHECK-3DVH system dose reconstruction have been comparatively analyzed with the criteria of 3 mm/3%, TH=10%, and their dose parameters for target volumes and organs at risk (OAR), such as D98%, D2%, Dmax, Dmean were also compared. Results The 3D γ-pass rate of treatment plans was 98.20% (97.75%, 99.20%), and the difference in parameters for target volumes D98%, D2%, Dmean between the TPS calculation dose and the ArcCHECK-3DVH dose reconstruction were mostly less than 3%, with a maximum difference of less than 5% in some individual cases. For most patients, the γ-pass rate for the whole target organs, except PGTVnd, were higher than 90%. Their difference in parameters for organs at risk (OAR) Dmax and Dmean were less than 6% and the γ-pass rates for OAR were above 93%. Conclusions The reconstruction doses by the ArcCHECK-3DVH system were in good agreement with the TPS calculation doses, which provide multiple parameters for the dose verification of VMAT plan for nasopharyngeal carcinoma, and can help the quality assurance of treatment plans.

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[1]吴爱林,吴爱东,耿国星,等.PTW729和ArcCheck探测器在调强放射治疗剂量验证中的应用[J].中国医学物理学杂志,2016,33(5):473.[doi:10.3969/j.issn.1005-202X.2016.05.009]
　[J].Chinese Journal of Medical Physics,2016,33(12):473.[doi:10.3969/j.issn.1005-202X.2016.05.009]
[2]王涛,程秀艳,郭跃信. ArcCheck的剂量学特性测量及其对VMAT计划的验证[J].中国医学物理学杂志,2019,36(3):277.[doi:DOI:10.3969/j.issn.1005-202X.2019.03.006]
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[4]闫冰,吴爱林,薛旭东,等.ArcCheck探测螺旋断层放疗误差的敏感性[J].中国医学物理学杂志,2021,38(6):666.[doi:DOI:10.3969/j.issn.1005-202X.2021.06.002]
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备注/Memo

备注/Memo:
【收稿日期】2020-05-13 【基金项目】广州市医药卫生科技项目（20181A011095） 【作者简介】阳露，硕士研究生，主要研究方向：医学物理，E-mail: fiona- xiaoxuan@163.com 【通信作者】张书旭，博士，二级教授/主任技师，博士生导师，主要从事肿瘤精确放疗技术研究，E-mail: gthzsx@163.com
更新日期/Last Update: 2020-12-30