[1]刘小波,汪冬,赵云,等.KylinRay-IMRT与Pinnacle3胸部肿瘤计划剂量学比较分析[J].中国医学物理学杂志,2020,37(1):17-21.[doi:DOI:10.3969/j.issn.1005-202X.2020.01.004]
 LIU Xiaobo,WANG Dong,et al.Dosimetric comparison between KylinRay-IMRT and Pinnacle3 TPS in thoracic tumor plans[J].Chinese Journal of Medical Physics,2020,37(1):17-21.[doi:DOI:10.3969/j.issn.1005-202X.2020.01.004]
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KylinRay-IMRT与Pinnacle3胸部肿瘤计划剂量学比较分析()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
37
期数:
2020年第1期
页码:
17-21
栏目:
医学放射物理
出版日期:
2020-01-10

文章信息/Info

Title:
Dosimetric comparison between KylinRay-IMRT and Pinnacle3 TPS in thoracic tumor plans
文章编号:
1005-202X(2020)01-0017-05
作者:
刘小波12汪冬1赵云1郑华庆1贾婧1宋婧1
1.中国科学院核能安全技术研究所,中子输运理论与辐射安全重点实验室, 安徽 合肥 230031; 2.中国科学技术大学, 安徽 合肥 230026
Author(s):
LIU Xiaobo1 2 WANG Dong1 ZHAO Yun1 ZHENG Huaqing1 JIA Jing1 SONG Jing1
1. Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei 230031, China; 2. University of Science and Technology of China, Hefei 230026, China
关键词:
调强放射治疗治疗计划系统软件测试剂量学计划比较
Keywords:
Keywords: intensity-modulated radiotherapy treatment planning system software test dosimetry plan comparison
分类号:
R811.1;R730.55
DOI:
DOI:10.3969/j.issn.1005-202X.2020.01.004
文献标志码:
A
摘要:
IMRT 5.0的逆向计划优化功能。方法:从例题库选取15例胸部例题并导入至调强放射治疗计划系统KylinRay-IMRT,在KylinRay-IMRT计划系统中进行优化计算并确认优化结果,从TPS提取剂量学指标值并记录,数据比较进行t检验。结果:两组TPS计划的靶区均匀性指数(HI)、适形度指数(CI)、剂量分布满足临床要求,KylinRay-IMRT计划在靶区HI上略优于对照TPS组(t=4.480;P=0.001)。KylinRay-IMRT计划肺的V10、V20、V30、平均剂量(t=2.594、6.672、3.471、6.225;P<0.05)略优于对照TPS组,心脏的V30、V40、平均剂量(t=6.078、6.466、8.712;P<0.05)明显优于对照TPS组。两组靶区CI(t=-1.548;P=0.144)、肺的V5(t=1.339;P=0.202)、脊髓最大剂量(t=1.465;P=0.165)无统计学意义。结论:对于胸部例题而言,由于TPS自身因素和人为因素导致两者计算结果存在差异,KylinRay-IMRT的计划质量在临床可接受的程度范围内,其逆向计划优化功能满足了临床应用的安全性和准确性要求。
Abstract:
Abstract: Objective To verify and evaluate the capability of inverse planning optimization of KylinRay-IMRT 5.0 for intensity-modulated radiotherapy (IMRT) by analyzing the quality of planning optimizations with two different treatment planning systems (TPS). Methods Fifteen thoracic tumor plans selected from case database were imported into KylinRay-IMRT for optimization calculations, and the optimization results were confirmed with those of Pinnacle3 TPS. The dosimetric index values selected from TPS were obtained and compared with t test. Results The homogeneity index, conformity index and dose distribution of two kinds of TPS plans satisfied the clinical requirements. The homogeneity index of target areas in KylinRay-IMRT plan was slightly better than that in control TPS plan (t=4.480; P=0.001). The V10, V20, V30 and mean dose of lungs in KylinRay-IMRT plan were slightly better than those in control TPS plan (t=2.594, 6.672, 3.471, 6.225; P<0.05), and the V30, V40 and mean dose of heart in KylinRay-IMRT plan were superior to those in control TPS plan (t=6.078, 6.466, 8.712; P<0.05). No statistical significance was found in the conformity index of target areas (t=-1.548; P=0.144), lung-V5 (t=1.339; P=0.202) and the maximum dose to spinal cord (t=1.465; P=0.165). Conclusion For cases of thoracic tumors, there are differences in the optimization outcomes of the two TPS due to TPS itself and human factors. The quality of KylinRay-IMRT plan is proved to be within the acceptable range, and its capability of inverse planning optimization satisfies the requirements of clinical safety and validity.

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备注/Memo

备注/Memo:
【收稿日期】2019-06-14 【基金项目】国家自然科学基金(11605233);中国科学院合肥物质科学研究院院长基金(YZJJ201618) 【作者简介】刘小波,主要研究方向:放射医学物理,E-mail: xiaobo.liu- @fds.org.cn 【通信作者】贾婧,副研究员,主要研究方向:医学物理,E-mail: jing.jia@fds.org.cn;宋婧,副研究员,主要研究方向:医学物理,E-mail: jing.song@fds.org.cn
更新日期/Last Update: 2020-01-14