[1]秦丹丹,韩济华,戴婷婷,等.VMAT和IMRT技术在直肠癌患者术后放疗中的剂量学比较[J].中国医学物理学杂志,2026,43(7):857-860.[doi:DOI:10.3969/j.issn.1005-202X.2026.07.004]
 QIN Dandan,HAN Jihua,DAI Tingting,et al.Dosimetric comparison of VMAT and IMRT in postoperative radiotherapy for rectal cancer patients[J].Chinese Journal of Medical Physics,2026,43(7):857-860.[doi:DOI:10.3969/j.issn.1005-202X.2026.07.004]
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VMAT和IMRT技术在直肠癌患者术后放疗中的剂量学比较()

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
43卷
期数:
2026年第7期
页码:
857-860
栏目:
医学放射物理
出版日期:
2026-07-22

文章信息/Info

Title:
Dosimetric comparison of VMAT and IMRT in postoperative radiotherapy for rectal cancer patients
文章编号:
1005-202X(2026)07-0857-04
作者:
秦丹丹1韩济华1戴婷婷1杨春2
1.淮安市第一人民医院放疗科, 江苏 淮安 223300;2.淮安市第二人民医院放疗科, 江苏 淮安 223002
Author(s):
QIN Dandan1 HAN Jihua1 DAI Tingting1 YANG Chun2
1. Department of Radiotherapy, Huaian First Peoples Hospital, Huaian 223300, China 2. Department of Radiotherapy, Huaian Second Peoples Hospital, Huaian 223002, China
关键词:
直肠癌放射治疗容积旋转调强固定野调强剂量学
Keywords:
rectal cancer radiotherapy volumetric modulated arc therapy intensity-modulated radiotherapy dosimetry
分类号:
R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2026.07.004
文献标志码:
A
摘要:
目的:比较分析容积旋转调强放射治疗(VMAT)和固定野调强放射治疗(IMRT)技术在直肠癌患者术后放射治疗中的剂量学。方法:选取37例直肠癌术后患者,进行CT模拟定位,靶区和危及器官勾画,在同一CT图像上用治疗计划系统进行IMRT和VMAT计划设计,处方剂量给予50 Gy/25次,使用相同的剂量约束条件,比较两种计划的靶区平均剂量、适形度指数(CI)、均匀性指数(HI)、危及器官受照剂量、机器跳数及治疗时间。结果:两种治疗计划均能满足临床剂量要求,VMAT计划的靶区平均剂量略高于IMRT计划,HI、CI均优于IMRT,差异有统计学意义(P<0.05)。IMRT和VMAT计划中重要的危及器官(膀胱和股骨头)受照剂量比较差异无统计学意义(P>0.05)。VMAT计划的机器跳数少于IMRT计划,预估出束时间短于IMRT计划,差异有统计学意义(P<0.05)。结论:VMAT和IMRT技术应用于直肠癌患者术后放射治疗中均可满足临床要求,VMAT计划可以显著减少机器跳数,缩短治疗时间。
Abstract:
Abstract: Objective To compare and analyze dosimetric differences of volumetric modulated arc therapy (VMAT) and intensity-modulated radiation therapy (IMRT) in postoperative radiotherapy for patients with rectal cancer. Methods Thirty-seven patients with rectal cancer were enrolled. CT simulation was performed, followed by target volume and organs-at-risk delineation. IMRT and VMAT plans were generated on the same CT image using the treatment planning system, with a prescribed dose of 50 Gy in 25 factions and the identical dose constraints. The two plans were compared in terms of mean target dose, conformity index (CI), homogeneity index (HI), doses to organs-at-risk, monitor unit, and delivery time. Results Both treatment plans met clinical dose criteria. Compared with IMRT, VMAT achieved a slightly higher mean target dose and superior HI and CI, with statistically significant differences (P<0.05). No significant inter-plan differences were observed in the doses delivered to important organs-at-risk (bladder and femoral heads) (P>0.05). In addition, VMAT required fewer monitor units and shorter delivery time relative to IMRT (P<0.05). Conclusion Both VMAT and IMRT satisfies the clinical requirements for postoperative radiotherapy of patients with rectal cancer. VMAT can significantly reduce monitor unit and shorten delivery time.

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备注/Memo

备注/Memo:
【收稿日期】2025-12-04 【基金项目】江苏省卫生健康委科研项目(Z2023A071) 【作者简介】秦丹丹,技师,研究方向:放疗技术,E-mail: qindd1009@163.com 【通信作者】韩济华,硕士,主任技师,研究方向:放疗技术,E-mail: han10092024@163.com
更新日期/Last Update: 2026-07-22