[1]邓永明,程希元,胡星源,等.基于国产直线加速器联影URT-linac 506c不同图像引导方式的辐射剂量与图像质量测量[J].中国医学物理学杂志,2025,42(12):1541-1547.[doi:DOI:10.3969/j.issn.1005-202X.2025.12.001]
　DENG Yongming,CHENG Xiyuan,HU Xingyuan,et al.Measurement of radiation dose and imaging quality based on different image guidance methods for the URT-linac 506c[J].Chinese Journal of Medical Physics,2025,42(12):1541-1547.[doi:DOI:10.3969/j.issn.1005-202X.2025.12.001]
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基于国产直线加速器联影URT-linac 506c不同图像引导方式的辐射剂量与图像质量测量()

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
42
期数:
2025年第12期
页码:
1541-1547
栏目:
医学放射物理
出版日期:
2025-12-29

文章信息/Info

Title:
Measurement of radiation dose and imaging quality based on different image guidance methods for the URT-linac 506c
文章编号:
1005-202X（2025）12-1541-07
作者:
邓永明1; 程希元2; 胡星源1; 谭佩欣1; 吕凤泉1
1.南方医科大学附属广东省人民医院（广东省医学科学院）放疗科， 广东 广州 510080； 2.广州南医宜康医疗设备股份有限公司， 广东 广州 510515
Author(s):
DENG Yongming1;  CHENG Xiyuan2;  HU Xingyuan1;  TAN Peixin1;  L?Fengquan1
1. Department of Radiation Oncology, Guangdong Provincial Peoples Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China 2. Guangzhou Nanyi Yikang Medical Equipment Co., Ltd., Guangzhou 510515, China
关键词:
URT-linac 506c; 图像引导放疗; 辐射剂量; CTDI模体; Catphan504
Keywords:
Keywords: URT-linac 506c image-guided radiotherapy radiation dose CTDI phantom Catphan504
分类号:
R318.6；R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2025.12.001
文献标志码:
A
摘要:
目的：比较分析国产直线加速器联影URT-linac 506c自带电子射野影像系统（EPID）、兆伏级锥形束CT（MV-CBCT）和千伏级扇形束CT（kV-FBCT）用于调强放射治疗图像引导成像（IGRT）时的辐射剂量和成像质量，为临床选择合适IGRT提供数据支持。方法：采用圆柱形有机玻璃模体、PTW 300013指形电离室、Unfors Xi笔形电离室和Catphan504模体测量联影URT-linac 506c自带的EPID、MV-CBCT和kV-FBCT系统各种扫描协议下的辐射剂量和成像质量参数。EPID采用0°和90°正交野成像，MV-CBCT采用CBCT成像，kV-FBCT采用螺旋CT成像，计算各种IGRT方式加权辐射剂量和图像质量参数，分析比较各扫描协议的辐射剂量和成像质量参数差异。结果：在联影IGRT模式中，EPID、MV-CBCT Half Scan、MV-CBCT Full Scan/Half Fan和kV-FBCT的图像引导耗时分别为（80.80±1.30） s、（75.00±2.92） s、（98.60±1.67） s和（77.40±1.94） s，差异有统计学意义（Z=15.892, P=0.001）。在辐射剂量方面，EPID成像剂量低于MV-CBCT和kV-FBCT成像剂量。EPID、MV-CBCT和kV-FBCT最小辐射剂量分别为（2.30±0.67） mGy、（13.01±0.84） mGy和（8.17±0.40） mGy。在图像质量方面，kV-FBCT成像质量高于MV-CBCT和EPID。kV-FBCT组均能分辨6组线对，空间分辨率为0.83 mm；MV-CBCT组最多只能分辨4组线对，空间分辨率为1.25 mm；EPID组虽然能分辨出11组线对，空间分辨率为0.46 mm，但图像噪声水平和密度分辨率较差。结论：对于儿童病人及头颈部病人，建议尽量采用低剂量模式的kV-FBCT扫描方案；对于胸、盆腔部扫描，也建议采用低剂量模式的kV-FBCT扫描方案。
Abstract:
Abstract: Objective To compare and analyze the radiation doses and imaging quality of the built-in electronic portal imaging device (EPID), megavoltage cone-beam computed tomography (MV-CBCT), and kilovoltage fan-beam computed tomography (kV-FBCT) in the domestic linear accelerator United Imaging URT-linac 506c for image-guided radiotherapy (IGRT), thereby providing data support for the clinical selection of appropriate IGRT modalities. Methods Cylindrical polymethyl methacrylate phantoms, PTW 300013 finger ionization chambers, Unfors Xi pencil ionization chambers, and Catphan504 phantoms were used to measure the radiation doses and imaging quality parameters of the EPID, MV-CBCT, and kV-FBCT systems of United Imaging URT-linac 506c under various scanning protocols. Specifically, EPID imaging was conducted using 0° and 90° orthogonal fields MV-CBCT was performed in the CBCT imaging mode and kV-FBCT was operated in the spiral CT imaging mode. The weighted radiation doses and imaging quality parameters of various IGRT modalities were calculated, and the differences in radiation doses and imaging quality parameters among different scanning protocols were analyzed and compared. Results In the IGRT mode of URT-linac 506c, the time consumption for image guidance using EPID, MV-CBCT Half Scan, MV-CBCT Full Scan/Half Fan, and kV-FBCT was (80.80±1.30), (75.00±2.92), (98.60±1.67), and (77.40±1.94) s, respectively, with statistically significant differences (Z=15.894, P=0.001). In terms of radiation dose, the imaging dose of EPID was lower than that of MV-CBCT and kV-FBCT and the minimum radiation doses of EPID, MV-CBCT and kV-FBCT were (2.30±0.67), (13.01±0.84), and (8.17±0.40) mGy, respectively. Regarding imaging quality, kV-FBCT outperformed both MV-CBCT and EPID. Specifically, kV-FBCT group could identify 6 line pairs, with a spatial resolution of 0.83 mm, while MV-CBCT group only resolve a maximum of 4 line pairs, with a spatial resolution of 1.25 mm. Although the EPID group was capable of distinguishing 11 line pairs, achieving a spatial resolution of 0.46 mm, it had inferior image noise level and density resolution. Conclusion The low-dose kV-FBCT scanning protocol is preferred for pediatric patients and patients with head and neck lesions. For thoracic and pelvic scans, low-dose mode kV-FBCT scanning protocol is also recommended.

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备注/Memo

备注/Memo:
【收稿日期】2025-05-07 【基金项目】国家自然科学基金（82203963）；广州市科技计划基金（2024A04J10022） 【作者简介】邓永明，工程师，研究方向：医学物理技术应用，E-mail: dymnlfd@163.com 【通信作者】吕凤泉，工程师，研究方向：放射治疗学研究，E-mail: lvfengquan@gdph.org.cn；谭佩欣，主治医师，研究方向：放射性损伤，E-mail: tpxsaxin@163.com（吕凤泉和谭佩欣为共同通信作者）
更新日期/Last Update: 2025-12-29