[1]罗忠亮,贾应彪.基于高斯过程和Radon变换的视网膜血管管径测量[J].中国医学物理学杂志,2022,39(11):1377-1384.[doi:DOI:10.3969/j.issn.1005-202X.2022.11.010]
　LUO Zhongliang,JIA Yingbiao.Measurement of retinal vessel diameter using Gaussian process and Radon transform[J].Chinese Journal of Medical Physics,2022,39(11):1377-1384.[doi:DOI:10.3969/j.issn.1005-202X.2022.11.010]
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基于高斯过程和Radon变换的视网膜血管管径测量()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
39卷
期数:
2022年第11期
页码:
1377-1384
栏目:
医学影像物理
出版日期:
2022-11-25

文章信息/Info

Title:
Measurement of retinal vessel diameter using Gaussian process and Radon transform
文章编号:
1005-202X（2022）11-1377-08
作者:
罗忠亮; 贾应彪
韶关学院信息工程学院， 广东 韶关 512005
Author(s):
LUO Zhongliang;  JIA Yingbiao
School of Information Engineering, Shaoguan University, Shaoguan 512005, China
关键词:
视网膜血管管径测量; 眼底图像; 高斯过程; Radon变换
Keywords:
retinal vessel diameter measurement fundus image Gaussian process Radon transform
分类号:
R318；TP391.4
DOI:
DOI:10.3969/j.issn.1005-202X.2022.11.010
文献标志码:
A
摘要:
视网膜血管管径的异常变化与糖尿病、高血压等心脑血管疾病发展进程息息相关，眼底图像中视网膜血管信息的提取是计算机辅助分析和诊断相关疾病的重要步骤。本研究提出一种视网膜血管管径测量方法。首先对眼底图像进行图像预处理，然后基于高斯过程和Radon变换准确跟踪血管中心线和方向，最后利用二维高斯过程回归技术测量血管管径。在DRIVE和STARE这两个眼底图像数据库中进行测试。结果表明不论是对于曲率较小的近似直线型血管段、曲率较大的弯曲型血管段，还是对于管径发生变化的血管段，本文方法都能较好地检测出血管管径宽度，且标准差低、运算速度快。
Abstract:
The abnormal changes of retinal vessel diameter are closely associated with the development of cardiovascular and cerebrovascular diseases such as diabetes and hypertension. Therefore, the extraction of retinal vessel information in fundus images is significant for computer-aided analysis and diagnosis of related diseases. Herein a novel method for the measurement of retinal vessel diameter is presented. After fundus image preprocessing, Gaussian process and Radon transform are used to track the center lines and directions of retinal vessel, and then the retinal vessel diameter is estimated using two-dimensional Gaussian process regression technology. The fundus image databases of DRIVE and STARE are used for testing. The results reveal that whether for approximately linear vessel segments with small curvature, curved vessel segments with large curvature, or vessel segments with changes in diameter, the proposed method can measure the retinal vessel diameter efficiently, with low standard deviation and high operation speed.

相似文献/References:

[1]张嘉阳,黄河,刘子怡,等. 基于Gabor滤波器的糖尿病视网膜新生血管检测[J].中国医学物理学杂志,2018,35(8):968.[doi:DOI:10.3969/j.issn.1005-202X.2018.08.019]
　ZHANG Jiayang,HUANG He,LIU Ziyi,et al. Gabor filter-based detection of neovascularization due to diabetic retinopathy[J].Chinese Journal of Medical Physics,2018,35(11):968.[doi:DOI:10.3969/j.issn.1005-202X.2018.08.019]
[2]王小芳,余柯欣,王张怡,等.基于超参数优化的TransCNN眼底图像分类算法[J].中国医学物理学杂志,2023,40(6):672.[doi:DOI:10.3969/j.issn.1005-202X.2023.06.003]
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备注/Memo

备注/Memo:
【收稿日期】2022-05-04 【基金项目】广东省自然科学基金（2016A030307044）；韶关市科技计划（200811114531562, 210720154531311） 【作者简介】罗忠亮，博士，教授，研究方向：信号与信息处理、人工智能，E-mail: luozl2004@163.com
更新日期/Last Update: 2022-11-25