卵巢正常大小癌综合征18F-FDGPET-CT表现-《中国医学物理学杂志》

文章信息/Info

作者:: 文政芳1; 岳军燕2; 谢文秀1; 赵淑珍1; 尹山兰1; 郭喆3; 1.新乡医学院第一附属医院妇产科，河南新乡 453100； 2.新乡医学院第一附属医院放射科，河南新乡453100； 3.南京医科大学第一附属医院核医学科，江苏南京 210000

Author(s):: WEN Zhengfang1; YUE Junyan2; XIE Wenxiu1; ZHAO Shuzhen1; YIN Shanlan1; GUO Zhe3; 1. Department of Obstetrics and Gynecology, the First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, China 2. Department of Radiology, the First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, China 3. Department of Nuclear Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China

Keywords:: Keywords: normal-sized ovary carcinoma syndrome 18F-fluorodeoxyglucose positron emission tomography ovarian papillary serous carcinoma extraovarian peritoneal serous papillary carcinoma

摘要:: 目的：探讨18氟-氟代脱氧葡萄糖（18F-FDG）正电子发射断层扫描（PET-CT）显像在卵巢正常大小癌综合征（NOCS）原发病灶确定、全身情况评估等方面的应用价值。方法：对6例行全身PET-CT检查并最终根据临床及病理结果确诊为NOCS患者的PET-CT影像资料进行回顾性分析。结果：6例患者中3例最终病理为卵巢浆液性乳头状癌，1例为卵巢外腹膜浆液性乳头状腺癌，1例为结肠癌转移，1例为非卵巢来源原因不明的转移性腺癌。18F-FDGPET-CT诊断卵巢癌2例，这2例患者PET-CT影像因腹腔积液的映衬卵巢CT影像清晰，并可见卵巢部位放射性摄取增高；PET-CT诊断卵巢外腹膜浆液性乳头状腺癌1例；1例PET-CT假阴性最终被确诊为卵巢癌；1例PET-CT未发现原发灶的患者最后诊断为肠道来源肿瘤。结论：18F-FDGPET-CT对于查找NOCS原发灶有一定的应用价值，卵巢浆液性乳头状癌是本文6例患者的主要组成部分，肿瘤标志物有一定提示意义。

Abstract:: Abstract: Objective To investigate the application value of 18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDGPET-CT) in detecting the primary lesion of normal-sized ovary carcinoma syndrome (NOCS) and assessing the general condition of patients. Methods The imaging data of 6 clinically- and pathologically-confirmed NOCS patients who underwent PET-CT examination were analyzed retrospectively. Results Three of the 6 cases were pathologically dignosed with ovarian papillary serous carcinoma, 1 with extraovarian peritoneal serous papillary carcinoma (EPSPC), 1 with intestinal tumor metastased from colon cancer, and the remaining 1 case with nonovarian adnocarcinoma with unknown origin. The PET-CT images of 2 cases of ovarian cancer diagnosed by 18F-FDGPET-CT showed massive ascites and well displayed ovaries against the massive ascites, and an increasing radioactivity uptake at ovarian was also demonstrated. There were 1 case of EPSPC diagnosed by PET-CT, 1 case of false-negative PET-CT findings which was finally confirmed as ovarian cancer and the case in which the original lesion was unknown was finally diagnosed with tumor originating from the intestine. Conclusion 18F-FDGPET-CT has certain value in detecting the original lesion of NOCS. Ovarian papillary serous carcinoma is the main component of the 6 NOCS cases, and tumor markers can be indicators in NOCS.