[1]邓靓娜,张国晋,张斌,等.周围型肺腺癌和周围型肺鳞癌的能谱CT表现[J].中国医学物理学杂志,2021,38(9):1097-1102.[doi:10.3969/j.issn.1005-202X.2021.09.009]
　DENG Liangna,,et al.Spectral CT findings of peripheral lung adenocarcinoma and peripheral lung squamous cellcarcinoma[J].Chinese Journal of Medical Physics,2021,38(9):1097-1102.[doi:10.3969/j.issn.1005-202X.2021.09.009]
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周围型肺腺癌和周围型肺鳞癌的能谱CT表现()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
38卷
期数:
2021年第9期
页码:
1097-1102
栏目:
医学影像物理
出版日期:
2021-09-26

文章信息/Info

Title:
Spectral CT findings of peripheral lung adenocarcinoma and peripheral lung squamous cell carcinoma
文章编号:
1005-202X（2021）09-1097-06
作者:
邓靓娜1; 2; 3; 张国晋1; 2; 3; 张斌1; 2; 3; 景梦园1; 2; 3; 韩涛1; 2; 3; 林晓强1; 2; 3; 周俊林1; 2; 3
1. 兰州大学第二医院放射科，甘肃兰州730030；2. 兰州大学第二临床医学院，甘肃兰州730000；3. 甘肃省医学影像重点实验 室，甘肃兰州730030
Author(s):
DENG Liangna1;  2;  3;  ZHANG Guojin1;  2;  3;  ZHANG Bin1;  2;  3;  JING Mengyuan1;  2;  3;  HAN Tao1;  2;  3;  LIN Xiaoqiang1;  2;  3;  ZHOU Junlin1;  2;  3
1. Department of Radiology, Lanzhou University Second Hospital, Lanzhou 730030, China 2. the Second School of Clinical Medicine, Lanzhou University, Lanzhou 730000, China 3. Key Laboratory of Medical Imaging in Gansu Province, Lanzhou 730030, China
关键词:
肺癌; 能谱CT; 肺鳞癌; 肺腺癌; 鉴别诊断
Keywords:
lung cancer spectral CT lung squamous cell carcinoma lung adenocarcinoma differential diagnosis
分类号:
R734.2；R816.41
DOI:
10.3969/j.issn.1005-202X.2021.09.009
文献标志码:
A
摘要:
目的：观察周围型肺腺癌和周围型肺鳞癌的能谱CT表现。方法：回顾性分析经病理证实并行能谱CT扫描的周围 型肺腺癌122 例和周围型肺鳞癌89 例。测量病灶在动脉期及静脉期下的CT40 keV值、CT70 keV值、CT100 keV值、碘（水）浓度 （IC）、水（碘）浓度（WC）和有效原子序数（Zeff），并计算能谱曲线斜率（K70 keV）。比较两组之间各能谱参数之间的差异。结 果：两组之间性别差异有统计学意义（P<0.05），而其他临床特征和临床症状在两组之间差异无统计学意义（P>0.05）。动 脉期和静脉期，周围型肺腺癌的CT40 keV、CT70 keV、K70 keV、IC及Zeff均大于周围型肺鳞癌，差异具有统计学意义（P<0.05）；而 两组之间的WC和CT100 keV无统计学意义（P>0.05）。ROC曲线分析显示，动脉期各定量参数联合较静脉期各定量参数联 合的诊断效能好，曲线下面积、敏感性和特异性分别为86%、77%、83%。结论：周围型腺癌和周围型鳞癌的能谱CT表现 存在一定差异，可为二者的鉴别提供参考。
Abstract:
Objective To compare the spectral computed tomography (CT) findings of peripheral lung adenocarcinoma versus peripheral lung squamous cell carcinoma. Methods A total of 122 cases of peripheral lung adenocarcinoma and 89 cases of peripheral lung squamous cell carcinoma were analyzed retrospectively.All of these cases were proved by pathology and received energy spectral CT examination. The CT40 keV, CT70 keV, CT100 keV, iodine (water) concentration (IC), water (iodine) concentration (WC) and effective atomic number (Zeff) were measured in the arterial phase and the venous phase, and the slope of spectral curve (K70 keV) was calculated. The differences of spectral parameters between two groups were compared. Results There was no significant difference between two groups in clinical features and symptoms (P>0.05) except gender (P<0.05). In the arterial phase and the venous phase, the CT40 keV, CT70 keV, K70 keV, IC and Zeff of peripheral lung adenocarcinoma were higher than those of peripheral lung squamous cell carcinoma, with statistical differences (P<0.05), but no significant difference was found inWC and CT100 keV between two groups (P>0.05). Receiver operating characteristic curve analysis showed that the combination of quantitative parameters in the arterial phase had better diagnostic efficiency than the combination of quantitative parameters in the venous phase, and that the area under the curve, sensitivity and specificity of the former were 86%, 77%, and 83%, respectively. Conclusion There are some differences in spectral CT findings between peripheral lung adenocarcinoma and peripheral lung squamous cell carcinoma, which can provide reference for the differential diagnosis.

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备注/Memo

备注/Memo:
【收稿日期】2021-02-25 【基金项目】甘肃省医学影像重点实验室开放基金项目（GSYX202010）； 中央高校基本科研业务费专项资金资助（lzujbky-2021-kb32） 【作者简介】邓靓娜，硕士，研究方向：胸部影像学，E-mail: 2312844186- @qq.com 【通信作者】周俊林，博士，主任医师，教授，研究方向：神经影像，Email: lzuzjl601@163.com
更新日期/Last Update: 2021-09-27