[1]陈日新,罗展雄,秦佳宁,等.早期乳腺癌保乳术后不同剂量调强放射治疗疗效比较[J].中国医学物理学杂志,2020,37(8):993-995.[doi:DOI:10.3969/j.issn.1005-202X.2020.08.010]
 CHEN Rixin,LUO Zhanxiong,QIN Jianing,et al.Comparison of therapeutic effects of intensity-modulated radiotherapy with different dose schemes following breast-conserving surgery for early-stage breast cancer[J].Chinese Journal of Medical Physics,2020,37(8):993-995.[doi:DOI:10.3969/j.issn.1005-202X.2020.08.010]
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早期乳腺癌保乳术后不同剂量调强放射治疗疗效比较()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
37
期数:
2020年第8期
页码:
993-995
栏目:
医学放射物理
出版日期:
2020-08-27

文章信息/Info

Title:
Comparison of therapeutic effects of intensity-modulated radiotherapy with different dose schemes following breast-conserving surgery for early-stage breast cancer
文章编号:
1005-202X(2020)08-0993-03
作者:
陈日新1罗展雄1秦佳宁1朱州1贾燕华1王志2
1.柳州市人民医院肿瘤内科, 广西 柳州 545006; 2.湘南学院附属医院全科医疗科, 湖南 郴州 423000
Author(s):
CHEN Rixin1 LUO Zhanxiong1 QIN Jianing1 ZHU Zhou1 JIA Yanhua1 WANG Zhi2
1. Department of Medical Oncology, Liuzhou Peoples Hospital, Liuzhou 545006, China 2. Department of General Practice, Affiliated Hospital of Xiangnan University, Chenzhou 423000, China
关键词:
乳腺癌保乳术调强放射治疗放射剂量
Keywords:
Keywords: breast cancer breast-conserving surgery intensity-modulated radiotherapy irradiation dose
分类号:
R730.55;R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2020.08.010
文献标志码:
A
摘要:
目的:分析早期乳腺癌保乳术后不同剂量调强放射治疗效果。方法:接受手术治疗的乳腺癌患者50例,依据不同放射剂量分组:A组放疗总剂量50 Gy,B组放疗总剂量60 Gy,观察两种方案的干预效果及安全性。结果:两组患者在V100%上并无差异,分别为(55.13±6.28)%和(54.26±6.01)%;在V99%、V109%、V115%等比较均存在显著差异(P<0.05)。A组3年复发率12%,高于B组的4%(P<0.05);A组患者Ⅰ级及以下放射性皮炎发生率44.00%,显著低于B组的72.00%(P<0.05),两组Ⅱ级与Ⅲ级及以上放射性皮炎发生率无显著差异。结论:早期乳腺癌患者以保乳术作为主要治疗方案,放射疗法属于关键辅助措施,不同剂量影响治疗效果,适当增大剂量有助于提升整体疗效。
Abstract:
Abstract: Objective To analyze the therapeutic effects of intensity-modulated radiotherapy with different dose schemes after breast-conserving therapy for early-stage breast cancer. Methods Fifty patients receiving surgery for breast cancer were divided into two groups according to the irradiation dose. The total radiotherapy dose was 50 Gy in group A and 60 Gy in group B. The intervention effect and safety of the two schemes were analyzed. Results There were significant differences between two groups in V99%, V109% and V115% (P<0.05), but not in V100% [(55.13±6.28)% vs (54.26±6.01)%]. The 3-year?elapse rate in group A was 12%, higher than 4% in group B (P<0.05). Moreover, the incidence of radiodermatitis of grade Ⅰ and below in group A was obviously lower than that in group B (44.00% vs 72.00%, P<0.05), and no significant difference was found in the incidence of radiodermatitis of grade Ⅱ and grade III and above. Conclusion The main treatment scheme for patients with early-stage breast cancer is breast-conserving therapy, and the key auxiliary measure is radiotherapy in which different dose schemes can affect the therapeutic effect, and an appropriate high dose scheme can improve the overall therapeutic effect.

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备注/Memo

备注/Memo:
【收稿日期】2020-01-13 【基金项目】广西壮族自治区卫健委课题(Z20180289) 【作者简介】陈日新,副主任医师,E-mail: shijing100314@sina.com 【通信作者】王志,硕士,主治医师,研究方向:全科医学,E-mail: ww55- 0783@163.com
更新日期/Last Update: 2020-08-27